Informacja

Drogi użytkowniku, aplikacja do prawidłowego działania wymaga obsługi JavaScript. Proszę włącz obsługę JavaScript w Twojej przeglądarce.

Przeglądasz jako GOŚĆ
Zmień bibliotekę
Tytuł pozycji:

Prediction of lymph node manifestations in malignant lymphoma: significant role of volumetric compared with established metric lymph node analysis in multislice computed tomography.

Tytuł :
Prediction of lymph node manifestations in malignant lymphoma: significant role of volumetric compared with established metric lymph node analysis in multislice computed tomography.
Autorzy :
Puesken M; Department of Clinical Radiology, University Hospital Muenster, Muenster, Germany. />Buerke B
Gerss J
Frisch B
Beyer F
Weckesser M
Seifarth H
Heindel W
Wessling J
Pokaż więcej
Źródło :
Journal of computer assisted tomography [J Comput Assist Tomogr] 2010 Jul; Vol. 34 (4), pp. 564-9.
Typ publikacji :
Journal Article
Język :
English
Imprint Name(s) :
Publication: <2000->: Hagerstown, MD : Lippincott Williams & Wilkins
Original Publication: New York, Raven Press.
MeSH Terms :
Lymph Nodes/*diagnostic imaging
Lymphoma/*diagnostic imaging
Positron-Emission Tomography/*methods
Tomography, X-Ray Computed/*methods
Adolescent ; Adult ; Aged ; Aged, 80 and over ; Cone-Beam Computed Tomography/methods ; Contrast Media ; Diagnosis, Differential ; Female ; Humans ; Imaging, Three-Dimensional/methods ; Iohexol/analogs & derivatives ; Male ; Middle Aged ; Observer Variation ; Predictive Value of Tests ; ROC Curve ; Radiographic Image Enhancement/methods ; Reproducibility of Results ; Whole Body Imaging/methods ; Young Adult
Substance Nomenclature :
0 (Contrast Media)
4419T9MX03 (Iohexol)
712BAC33MZ (iopromide)
Entry Date(s) :
Date Created: 20100727 Date Completed: 20100820 Latest Revision: 20161125
Update Code :
20211214
DOI :
10.1097/RCT.0b013e3181db2901
PMID :
20657226
Czasopismo naukowe
Objective: Comparison of 2-dimensional and semiautomated 3-dimensional (3D) measurements to distinguish between benign and malignant lymph nodes in patients with malignant lymphoma.
Methods: Whole-body positron emission tomography-computed tomography (PET-CT) was performed in 33 patients before therapy for malignant lymphoma. Two hundred fifty-seven peripheral lymph nodes (mean size, 13.4 +/- 5.4 mm) were evaluated independently by 2 radiologists, both manually and with the use of semiautomated segmentation software. Long-axis diameter (LAD), short-axis diameter (SAD), maximal 3D diameter, volume, and elongation were measured. Positron emission tomography-CT and PET-CT follow-up and/or histology served as the reference standard. Statistical analysis encompassed intraclass correlation coefficients and receiver operating characteristic curves.
Results: The standard of reference revealed involvement in 116 (45%) of 257 lymph nodes. Manual and semiautomated LAD and SAD showed good correlation with intraclass coefficients of 0.85 and 0.72, respectively. Semiautomated prediction of malignant lymph nodes revealed the highest areas under the receiver operating characteristic curves for volume (0.760; 95% confidence interval [CI], 0.639-0.887) followed by SAD (0.740; 95% CI, 0.616-0.862). The findings for LAD (0.722; 95% CI, 0.588-0.855), maximal 3D diameter (0.697; 95% CI, 0.565-0.830), and lymph node elongation (0.605; 95% CI, 0.466-0.745) were significantly lower (P < 0.05).
Conclusions: Volumetric lymph node analysis is significantly superior compared with established LAD in the prediction of lymph node involvement and therefore can add to the definition of peripheral lymphoma target lesions.

Ta witryna wykorzystuje pliki cookies do przechowywania informacji na Twoim komputerze. Pliki cookies stosujemy w celu świadczenia usług na najwyższym poziomie, w tym w sposób dostosowany do indywidualnych potrzeb. Korzystanie z witryny bez zmiany ustawień dotyczących cookies oznacza, że będą one zamieszczane w Twoim komputerze. W każdym momencie możesz dokonać zmiany ustawień dotyczących cookies