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Tytuł :
Comparison of the effect of rotenone and 1‑methyl‑4‑phenyl‑1,2,3,6‑tetrahydropyridine on inducing chronic Parkinson's disease in mouse models.
Autorzy :
Zhang J; Zhejiang Provincial Key Laboratory of Medical Genetics, School of Laboratory Medicine and Life Sciences, Wenzhou Medical University, Wenzhou, Zhejiang 325035, P.R. China.
Sun B; Department of Pathology, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang 310009, P.R. China.
Yang J; Zhejiang Provincial Key Laboratory of Medical Genetics, School of Laboratory Medicine and Life Sciences, Wenzhou Medical University, Wenzhou, Zhejiang 325035, P.R. China.
Chen Z; Zhejiang Provincial Key Laboratory of Medical Genetics, School of Laboratory Medicine and Life Sciences, Wenzhou Medical University, Wenzhou, Zhejiang 325035, P.R. China.
Li Z; Department of Internal Neurology, First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang 325035, P.R. China.
Zhang N; Department of Internal Neurology, First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang 325035, P.R. China.
Li H; Zhejiang Provincial Key Laboratory of Medical Genetics, School of Laboratory Medicine and Life Sciences, Wenzhou Medical University, Wenzhou, Zhejiang 325035, P.R. China.
Shen L; Department of Internal Neurology, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, P.R. China.
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Źródło :
Molecular medicine reports [Mol Med Rep] 2022 Mar; Vol. 25 (3). Date of Electronic Publication: 2022 Jan 18.
Typ publikacji :
Comparative Study; Journal Article
MeSH Terms :
Disease Models, Animal*
Parkinson Disease, Secondary/*metabolism
Parkinson Disease, Secondary/*physiopathology
1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine ; Animals ; Avoidance Learning/physiology ; Blotting, Western ; Chronic Disease ; DNA-Binding Proteins/metabolism ; Dopaminergic Neurons/cytology ; Glial Fibrillary Acidic Protein/metabolism ; Humans ; Immunohistochemistry ; Mice, Inbred C57BL ; Motor Activity/physiology ; Nerve Tissue Proteins/metabolism ; Parkinson Disease, Secondary/chemically induced ; Rotenone ; Substantia Nigra/cytology ; Tyrosine 3-Monooxygenase/metabolism
Czasopismo naukowe
Tytuł :
Amyloidosis in Alzheimer's Disease: Pathogeny, Etiology, and Related Therapeutic Directions.
Autorzy :
Ma C; Experimental Center of Pathogen Biology, Nanchang University, Nanchang 330006, China.; Queen Marry College, School of Medicine, Nanchang University, Nanchang 330036, China.
Hong F; Experimental Center of Pathogen Biology, Nanchang University, Nanchang 330006, China.
Yang S; Department of Physiology, College of Medicine, Nanchang University, Nanchang 330006, China.; Department of Physiology, Fuzhou Medical College, Nanchang University, Nanchang 344099, China.
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Źródło :
Molecules (Basel, Switzerland) [Molecules] 2022 Feb 11; Vol. 27 (4). Date of Electronic Publication: 2022 Feb 11.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Disease Susceptibility*
Alzheimer Disease/*etiology
Alzheimer Disease/*metabolism
Amyloidosis/*metabolism
Amyloidosis/*pathology
Alzheimer Disease/diagnosis ; Alzheimer Disease/therapy ; Amyloid/metabolism ; Amyloid beta-Peptides/metabolism ; Amyloidosis/diagnosis ; Amyloidosis/therapy ; Animals ; Autophagy ; Biomarkers ; Brain/blood supply ; Brain/metabolism ; Brain/pathology ; Brain/physiopathology ; Disease Management ; Gene Expression Regulation ; Humans ; Plaque, Amyloid/metabolism ; Plaque, Amyloid/pathology ; Risk Factors
Czasopismo naukowe
Tytuł :
COPD profiles and treatable traits using minimal resources: identification, decision tree and stability over time.
Autorzy :
Marques A; Lab3R - Respiratory Research and Rehabilitation Laboratory, School of Health Sciences, University of Aveiro (ESSUA), Agras do Crasto - Campus Universitário de Santiago, Edifício 30, 3810-193, Aveiro, Portugal. .; iBiMED - Institute of Biomedicine, Department of Medical Sciences, University of Aveiro, Agras do Crasto - Campus Universitário de Santiago, Edifício 30, 3810-193, Aveiro, Portugal. .
Souto-Miranda S; Lab3R - Respiratory Research and Rehabilitation Laboratory, School of Health Sciences, University of Aveiro (ESSUA), Agras do Crasto - Campus Universitário de Santiago, Edifício 30, 3810-193, Aveiro, Portugal.; iBiMED - Institute of Biomedicine, Department of Medical Sciences, University of Aveiro, Agras do Crasto - Campus Universitário de Santiago, Edifício 30, 3810-193, Aveiro, Portugal.
Machado A; Lab3R - Respiratory Research and Rehabilitation Laboratory, School of Health Sciences, University of Aveiro (ESSUA), Agras do Crasto - Campus Universitário de Santiago, Edifício 30, 3810-193, Aveiro, Portugal.; iBiMED - Institute of Biomedicine, Department of Medical Sciences, University of Aveiro, Agras do Crasto - Campus Universitário de Santiago, Edifício 30, 3810-193, Aveiro, Portugal.
Oliveira A; Lab3R - Respiratory Research and Rehabilitation Laboratory, School of Health Sciences, University of Aveiro (ESSUA), Agras do Crasto - Campus Universitário de Santiago, Edifício 30, 3810-193, Aveiro, Portugal.; School of Rehabilitation Science, McMaster University, Hamilton, Canada.; West Park Healthcare Centre, Toronto, Canada.
Jácome C; Center for Health Technology and Services Research (CINTESIS) and Department of Community Medicine, Information and Health Decision Sciences (MEDCIDS), Faculty of Medicine, University of Porto, Porto, Portugal.
Cruz J; Centre for Innovative Care and Health Technology (ciTechCare), Polytechnic of Leiria, Leiria, Portugal.
Enes V; iBiMED - Institute of Biomedicine, Department of Medical Sciences, University of Aveiro, Agras do Crasto - Campus Universitário de Santiago, Edifício 30, 3810-193, Aveiro, Portugal.; Center for Research & Development in Mathematics and Applications (CIDMA), University of Aveiro, Aveiro, Portugal.
Afreixo V; Center for Research & Development in Mathematics and Applications (CIDMA), University of Aveiro, Aveiro, Portugal.
Martins V; Pulmonology Department, Hospital Distrital Figueira Foz, Figueira da Foz, Portugal.
Andrade L; Pulmonology Department, Centro Hospitalar do Baixo Vouga, Aveiro, Portugal.
Valente C; Pulmonology Department, Centro Hospitalar do Baixo Vouga, Aveiro, Portugal.
Ferreira D; Pulmonology Department, Centro Hospitalar do Médio Ave, Famalicão, Portugal.
Simão P; Pulmonology Department, Unidade Local de Saúde de Matosinhos, Matosinhos, Portugal.
Brooks D; School of Rehabilitation Science, McMaster University, Hamilton, Canada.; West Park Healthcare Centre, Toronto, Canada.
Tavares AH; Lab3R - Respiratory Research and Rehabilitation Laboratory, School of Health Sciences, University of Aveiro (ESSUA), Agras do Crasto - Campus Universitário de Santiago, Edifício 30, 3810-193, Aveiro, Portugal.; iBiMED - Institute of Biomedicine, Department of Medical Sciences, University of Aveiro, Agras do Crasto - Campus Universitário de Santiago, Edifício 30, 3810-193, Aveiro, Portugal.; Center for Research & Development in Mathematics and Applications (CIDMA), University of Aveiro, Aveiro, Portugal.
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Źródło :
Respiratory research [Respir Res] 2022 Feb 14; Vol. 23 (1), pp. 30. Date of Electronic Publication: 2022 Feb 14.
Typ publikacji :
Journal Article; Observational Study
MeSH Terms :
Decision Trees*
Disease Management*
Quality of Life*
Exercise/*physiology
Health Resources/*statistics & numerical data
Pulmonary Disease, Chronic Obstructive/*therapy
Aged ; Cross-Sectional Studies ; Disease Progression ; Female ; Humans ; Male ; Middle Aged ; Phenotype ; Portugal ; Prospective Studies ; Pulmonary Disease, Chronic Obstructive/physiopathology
Czasopismo naukowe
Tytuł :
Nickel particles are present in Crohn's disease tissue and exacerbate intestinal inflammation in IBD susceptible mice.
Autorzy :
Matsuda H; Department of Gastroenterology and Hepatology, Graduate School, Tokyo Medical and Dental University, Tokyo, Japan.
Nibe-Shirakihara Y; Department of Pathological Cell Biology, Medical Research Institute, Tokyo Medical and Dental University, Japan.
Tamura A; Department of Gastroenterology and Hepatology, Graduate School, Tokyo Medical and Dental University, Tokyo, Japan.
Aonuma E; Department of Gastroenterology and Hepatology, Graduate School, Tokyo Medical and Dental University, Tokyo, Japan.
Arakawa S; Department of Pathological Cell Biology, Medical Research Institute, Tokyo Medical and Dental University, Japan.
Otsubo K; Department of Gastroenterology and Hepatology, Graduate School, Tokyo Medical and Dental University, Tokyo, Japan.
Nemoto Y; Department of Gastroenterology and Hepatology, Graduate School, Tokyo Medical and Dental University, Tokyo, Japan.
Nagaishi T; Department of Advanced Therapeutics for G.I. Diseases, Tokyo Medical and Dental University, Tokyo, Japan.
Tsuchiya K; Department of Gastroenterology, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.
Shimizu S; Department of Pathological Cell Biology, Medical Research Institute, Tokyo Medical and Dental University, Japan.
Ma A; Department of Medicine, University of California, San Francisco, San Francisco, CA, USA.
Watanabe M; Advanced Research Institute, Tokyo Medical and Dental University, Tokyo, Japan.
Uo M; Department of Advanced Biomaterials, Tokyo Medical and Dental University, Tokyo, Japan.
Okamoto R; Department of Gastroenterology and Hepatology, Graduate School, Tokyo Medical and Dental University, Tokyo, Japan.
Oshima S; Department of Gastroenterology and Hepatology, Graduate School, Tokyo Medical and Dental University, Tokyo, Japan. Electronic address: .
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Źródło :
Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2022 Feb 12; Vol. 592, pp. 74-80. Date of Electronic Publication: 2022 Jan 01.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Disease Progression*
Crohn Disease/*pathology
Inflammation/*pathology
Intestines/*pathology
Nickel/*toxicity
Animals ; Autophagy/drug effects ; Autophagy-Related Protein 5/metabolism ; Dextran Sulfate ; Disease Susceptibility ; Humans ; Macrophages/drug effects ; Macrophages/pathology ; Macrophages/ultrastructure ; Mice, Inbred C57BL ; THP-1 Cells ; Tumor Necrosis Factor alpha-Induced Protein 3/metabolism
Czasopismo naukowe
Tytuł :
Novel Humanized Peripheral Blood Mononuclear Cell Mouse Model with Delayed Onset of Graft-versus-Host Disease for Preclinical HIV Research.
Autorzy :
Holguin L; Center for Gene Therapy, Beckman Research Institute of City of Hope, Duarte, California, USA.; Irell & Manella Graduate School of Biological Sciences, City of Hope, Duarte, California, USA.; Center for Comparative Medicine, City of Hope, Duarte, California, USA.
Echavarria L; Center for Gene Therapy, Beckman Research Institute of City of Hope, Duarte, California, USA.
Burnett JC; Center for Gene Therapy, Beckman Research Institute of City of Hope, Duarte, California, USA.; Irell & Manella Graduate School of Biological Sciences, City of Hope, Duarte, California, USA.
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Źródło :
Journal of virology [J Virol] 2022 Feb 09; Vol. 96 (3), pp. e0139421. Date of Electronic Publication: 2021 Nov 24.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Transplantation*/adverse effects
Cell Transplantation*/methods
Disease Models, Animal*
Graft vs Host Disease/*etiology
HIV Infections/*immunology
HIV Infections/*virology
Leukocytes, Mononuclear/*transplantation
Animals ; Disease Susceptibility ; Female ; HIV-1/immunology ; Humans ; Male ; Mice ; Mice, Knockout ; Research ; T-Lymphocyte Subsets/immunology ; T-Lymphocyte Subsets/metabolism ; Time Factors
Czasopismo naukowe
Tytuł :
The economic benefits of targeted response strategies against foot-and-mouth disease in Australia.
Autorzy :
Seitzinger AH; Land and Water and Health and Biosecurity Business Units, Commonwealth Scientific and Industrial Research Organization (CSIRO), Canberra, Australian Capital Territory 2601, Australia. Electronic address: .
Hafi A; Department of Agriculture, Water and the Environment, Australian Bureau of Agricultural and Resource Economics and Sciences (ABARES), Canberra, Australian Capital Territory 2601, Australia.
Addai D; Department of Agriculture, Water and the Environment, Australian Bureau of Agricultural and Resource Economics and Sciences (ABARES), Canberra, Australian Capital Territory 2601, Australia.
Garner G; Land and Water and Health and Biosecurity Business Units, Commonwealth Scientific and Industrial Research Organization (CSIRO), Canberra, Australian Capital Territory 2601, Australia.
Bradhurst R; Centre of Excellence for Biosecurity Risk Analysis, School of BioSciences, University of Melbourne, Parkville, Victoria 3010, Australia.
Breed AC; Department of Agriculture, Water and the Environment, Biosecurity Animal, Canberra, Australian Capital Territory 2601, Australia; School of Veterinary Science, University of Queensland, Brisbane, Queensland 4067 Australia.
Capon T; Land and Water and Health and Biosecurity Business Units, Commonwealth Scientific and Industrial Research Organization (CSIRO), Canberra, Australian Capital Territory 2601, Australia.
Miller C; Department of Agriculture, Water and the Environment, Biosecurity Animal, Canberra, Australian Capital Territory 2601, Australia.
Pinol J; Land and Water and Health and Biosecurity Business Units, Commonwealth Scientific and Industrial Research Organization (CSIRO), Canberra, Australian Capital Territory 2601, Australia; AgroParis Tech, Paris 75005, France.
Tapsuwan S; Land and Water and Health and Biosecurity Business Units, Commonwealth Scientific and Industrial Research Organization (CSIRO), Canberra, Australian Capital Territory 2601, Australia.
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Źródło :
Preventive veterinary medicine [Prev Vet Med] 2022 Jul; Vol. 204, pp. 105636. Date of Electronic Publication: 2022 Mar 31.
Typ publikacji :
Journal Article
MeSH Terms :
Cattle Diseases*/epidemiology
Foot-and-Mouth Disease*/epidemiology
Foot-and-Mouth Disease*/prevention & control
Foot-and-Mouth Disease Virus*
Vaccination*/veterinary
Animals ; Australia/epidemiology ; Cattle ; Disease Outbreaks/prevention & control ; Disease Outbreaks/veterinary
Czasopismo naukowe
Tytuł :
The use of wearable devices in chronic disease management to enhance adherence and improve telehealth outcomes: A systematic review and meta-analysis.
Autorzy :
Kamei T; Graduate School of Nursing Science, St Luke's International University, Tokyo, Japan.
Kanamori T; School of Nursing, Hamamatsu University School of Medicine, Hamamatsu, Japan.
Yamamoto Y; Chiba Faculty of Nursing, Tokyo Health Care University, Funabashi, Japan.
Edirippulige S; Centre for Online Health, Centre for Health Services Research, The University of Queensland, Australia.
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Źródło :
Journal of telemedicine and telecare [J Telemed Telecare] 2022 Jun; Vol. 28 (5), pp. 342-359. Date of Electronic Publication: 2020 Aug 20.
Typ publikacji :
Journal Article; Meta-Analysis; Systematic Review
MeSH Terms :
Diabetes Mellitus*/therapy
Pulmonary Disease, Chronic Obstructive*/therapy
Telemedicine*
Wearable Electronic Devices*
Chronic Disease ; Disease Management ; Humans ; Quality of Life
Czasopismo naukowe
Tytuł :
Immunogenicity of MultiTEP-Platform-Based Recombinant Protein Vaccine, PV-1950R, Targeting Three B-Cell Antigenic Determinants of Pathological α-Synuclein.
Autorzy :
Zagorski K; Department of Molecular Immunology, Institute for Molecular Medicine, Huntington Beach, CA 92647, USA.
Chailyan G; Department of Molecular Immunology, Institute for Molecular Medicine, Huntington Beach, CA 92647, USA.
Hovakimyan A; Department of Molecular Immunology, Institute for Molecular Medicine, Huntington Beach, CA 92647, USA.
Antonyan T; Department of Molecular Immunology, Institute for Molecular Medicine, Huntington Beach, CA 92647, USA.
Kiani Shabestari S; Institute for Memory Impairments and Neurological Disorders, University of California Irvine, Irvine, CA 92697, USA.; Sue and Bill Gross Stem Cell Research Center, University of California Irvine, Irvine, CA 92697, USA.
Petrushina I; Institute for Memory Impairments and Neurological Disorders, University of California Irvine, Irvine, CA 92697, USA.
Davtyan H; Institute for Memory Impairments and Neurological Disorders, University of California Irvine, Irvine, CA 92697, USA.; Sue and Bill Gross Stem Cell Research Center, University of California Irvine, Irvine, CA 92697, USA.
Cribbs DH; Institute for Memory Impairments and Neurological Disorders, University of California Irvine, Irvine, CA 92697, USA.
Blurton-Jones M; Institute for Memory Impairments and Neurological Disorders, University of California Irvine, Irvine, CA 92697, USA.; Sue and Bill Gross Stem Cell Research Center, University of California Irvine, Irvine, CA 92697, USA.
Masliah E; Laboratory of Neurogenetics, National Institute of Aging, National Institute of Health, Bethesda, MD 20814, USA.
Agadjanyan MG; Department of Molecular Immunology, Institute for Molecular Medicine, Huntington Beach, CA 92647, USA.
Ghochikyan A; Department of Molecular Immunology, Institute for Molecular Medicine, Huntington Beach, CA 92647, USA.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2022 May 29; Vol. 23 (11). Date of Electronic Publication: 2022 May 29.
Typ publikacji :
Journal Article
MeSH Terms :
Lewy Body Disease*/metabolism
Parkinson Disease*/metabolism
Vaccines, DNA*
Animals ; Antibodies ; Disease Models, Animal ; Epitopes, B-Lymphocyte ; Female ; Mice ; Recombinant Proteins ; alpha-Synuclein/metabolism
Czasopismo naukowe
Tytuł :
[Acute and chronic graft-versus-host disease after allogeneic hematopoietic stem cell transplantation].
Autorzy :
Barzin A; Service d'Hématologie, CHU Liège, Belgique.
Geurten C; Service d'Hématologie-Oncologie pédiatrique, CHU Liège, Belgique.
Willems E; Service d'Hématologie, CHU Liège, Belgique.
Baron F; Service d'Hématologie, CHU Liège, Belgique.; GIGA-I3, ULiège, Belgique.
Beguin Y; Service d'Hématologie, CHU Liège, Belgique.; GIGA-I3, ULiège, Belgique.
Servais S; Service d'Hématologie, CHU Liège, Belgique.; GIGA-I3, ULiège, Belgique.
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Transliterated Title :
Maladie du greffon contre l’hôte aiguë et chronique après allogreffe de cellules souches hématopoïétiques.
Źródło :
Revue medicale de Liege [Rev Med Liege] 2022 May; Vol. 77 (5-6), pp. 345-353.
Typ publikacji :
Journal Article
MeSH Terms :
Graft vs Host Disease*/etiology
Graft vs Host Disease*/prevention & control
Hematopoietic Stem Cell Transplantation*/adverse effects
Acute Disease ; Chronic Disease ; Humans ; Transplantation, Homologous/adverse effects
Czasopismo naukowe
Tytuł :
The Relationship Between Primary Thyroid Lymphoma and Various Types of Thyroid Autoimmunity: A Retrospective Cohort Study of 498 Cases, Including 9 Cases with Graves' Disease.
Autorzy :
Suzuki N; Department of Internal Medicine, Ito Hospital, Shibuya, Japan.
Watanabe N; Department of Internal Medicine, Ito Hospital, Shibuya, Japan.
Noh JY; Department of Internal Medicine, Ito Hospital, Shibuya, Japan.
Yoshimura R; Department of Internal Medicine, Ito Hospital, Shibuya, Japan.
Mikura K; Department of Internal Medicine, Ito Hospital, Shibuya, Japan.
Kinoshita A; Department of Internal Medicine, Ito Hospital, Shibuya, Japan.
Suzuki A; Department of Internal Medicine, Ito Hospital, Shibuya, Japan.
Mitsumatsu T; Department of Internal Medicine, Ito Hospital, Shibuya, Japan.
Fukushita M; Department of Internal Medicine, Ito Hospital, Shibuya, Japan.
Matsumoto M; Department of Internal Medicine, Ito Hospital, Shibuya, Japan.
Yoshihara A; Department of Internal Medicine, Ito Hospital, Shibuya, Japan.
Katoh R; Department of Pathology, Ito Hospital, Shibuya, Japan.
Sugino K; Department of Surgery, Ito Hospital, Shibuya, Japan.
Ito K; Department of Surgery, Ito Hospital, Shibuya, Japan.
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Źródło :
Thyroid : official journal of the American Thyroid Association [Thyroid] 2022 May; Vol. 32 (5), pp. 552-559. Date of Electronic Publication: 2022 Apr 12.
Typ publikacji :
Journal Article
MeSH Terms :
Graves Disease*
Hashimoto Disease*
Lymphoma*
Thyroid Neoplasms*
Aged ; Autoimmunity ; Genetic Predisposition to Disease ; Humans ; Middle Aged ; Retrospective Studies
Czasopismo naukowe
Tytuł :
Minor impact on fertility in men with inflammatory bowel disease: A National Cohort Study from Sweden.
Autorzy :
Druvefors E; Department of Surgery, County Hospital Ryhov, Jönköping, Sweden.; Department of Biomedical and Clinical Sciences, Faculty of Health Sciences, Linköping University, Linköping, Sweden.
Andersson RE; Department of Surgery, County Hospital Ryhov, Jönköping, Sweden.; Department of Biomedical and Clinical Sciences, Faculty of Health Sciences, Linköping University, Linköping, Sweden.
Hammar U; Department of Medical Sciences, Molecular Epidemiology, Uppsala University, Uppsala, Sweden.; Institute of environmental Medicine, Karolinska Institutet, Stockholm, Sweden.
Landerholm K; Department of Surgery, County Hospital Ryhov, Jönköping, Sweden.; Department of Biomedical and Clinical Sciences, Faculty of Health Sciences, Linköping University, Linköping, Sweden.
Myrelid P; Department of Biomedical and Clinical Sciences, Faculty of Health Sciences, Linköping University, Linköping, Sweden.; Department of Surgery, Linköping University Hospital, Linköping, Sweden.
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Źródło :
Alimentary pharmacology & therapeutics [Aliment Pharmacol Ther] 2022 Jul; Vol. 56 (2), pp. 292-300. Date of Electronic Publication: 2022 May 22.
Typ publikacji :
Journal Article
MeSH Terms :
Colitis, Ulcerative*/therapy
Crohn Disease*/complications
Crohn Disease*/epidemiology
Crohn Disease*/therapy
Inflammatory Bowel Diseases*/complications
Inflammatory Bowel Diseases*/epidemiology
Inflammatory Bowel Diseases*/therapy
Chronic Disease ; Cohort Studies ; Fertility ; Humans ; Male ; Registries ; Sweden/epidemiology
Czasopismo naukowe
Tytuł :
Causal Association Between Inflammatory Bowel Disease and Psoriasis: A Two-Sample Bidirectional Mendelian Randomization Study.
Autorzy :
Li Y; Department of Dermatology, Xiangya Hospital, Central South University, Changsha, China.; National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, China.
Guo J; Department of Dermatology, Xiangya Hospital, Central South University, Changsha, China.; National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, China.
Cao Z; National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, China.; Department of Spine Surgery and Orthopaedics, Xiangya Hospital, Central South University, Changsha, China.
Wu J; National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, China.; Department of Spine Surgery and Orthopaedics, Xiangya Hospital, Central South University, Changsha, China.
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Źródło :
Frontiers in immunology [Front Immunol] 2022 Jun 10; Vol. 13, pp. 916645. Date of Electronic Publication: 2022 Jun 10 (Print Publication: 2022).
Typ publikacji :
Journal Article
MeSH Terms :
Arthritis, Psoriatic*/complications
Colitis, Ulcerative*/complications
Colitis, Ulcerative*/genetics
Crohn Disease*/complications
Crohn Disease*/genetics
Inflammatory Bowel Diseases*/complications
Inflammatory Bowel Diseases*/genetics
Psoriasis*/complications
Psoriasis*/epidemiology
Psoriasis*/genetics
Genetic Predisposition to Disease ; Genome-Wide Association Study ; Humans ; Mendelian Randomization Analysis
Czasopismo naukowe
Tytuł :
Longitudinal evaluation of neuroinflammation and oxidative stress in a mouse model of Alzheimer disease using positron emission tomography.
Autorzy :
Rejc L; CIC biomaGUNE, Basque Research and Technology Alliance (BRTA), Paseo Miramon 182, 20014, San Sebastian, Spain. .
Gómez-Vallejo V; CIC biomaGUNE, Basque Research and Technology Alliance (BRTA), Paseo Miramon 182, 20014, San Sebastian, Spain.
Joya A; CIC biomaGUNE, Basque Research and Technology Alliance (BRTA), Paseo Miramon 182, 20014, San Sebastian, Spain.; Laboratory of Neuroimaging and biomarkers of inflammation, UPV/EHU, Sede building B. Sarriena, Achucarro Basque Center for Neuroscience, 48940, Science ParkLeioa, Spain.
Arsequell G; Institut de Química Avançada de Catalunya (IQAC), Spanish National Research Council (IQAC-CSIC), 08034, Barcelona, Spain.
Egimendia A; CIC biomaGUNE, Basque Research and Technology Alliance (BRTA), Paseo Miramon 182, 20014, San Sebastian, Spain.
Castellnou P; CIC biomaGUNE, Basque Research and Technology Alliance (BRTA), Paseo Miramon 182, 20014, San Sebastian, Spain.
Ríos-Anglada X; CIC biomaGUNE, Basque Research and Technology Alliance (BRTA), Paseo Miramon 182, 20014, San Sebastian, Spain.
Cossío U; CIC biomaGUNE, Basque Research and Technology Alliance (BRTA), Paseo Miramon 182, 20014, San Sebastian, Spain.
Baz Z; CIC biomaGUNE, Basque Research and Technology Alliance (BRTA), Paseo Miramon 182, 20014, San Sebastian, Spain.
Iglesias L; Laboratory of Neuroimaging and biomarkers of inflammation, UPV/EHU, Sede building B. Sarriena, Achucarro Basque Center for Neuroscience, 48940, Science ParkLeioa, Spain.
Capetillo-Zarate E; Faculty of Medicine and Nursery, University of the Basque Country UPV/EHU, Achucarro Basque Center for Neuroscience and CIBERNED, Barrio Sarriena S/N, 48940, Leioa, Spain.; Basque Foundation for Science, IKERBASQUE, 48009, Bilbao, Spain.
Ramos-Cabrer P; CIC biomaGUNE, Basque Research and Technology Alliance (BRTA), Paseo Miramon 182, 20014, San Sebastian, Spain.; Basque Foundation for Science, IKERBASQUE, 48009, Bilbao, Spain.
Martin A; Laboratory of Neuroimaging and biomarkers of inflammation, UPV/EHU, Sede building B. Sarriena, Achucarro Basque Center for Neuroscience, 48940, Science ParkLeioa, Spain.; Basque Foundation for Science, IKERBASQUE, 48009, Bilbao, Spain.
Llop J; CIC biomaGUNE, Basque Research and Technology Alliance (BRTA), Paseo Miramon 182, 20014, San Sebastian, Spain. .
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Źródło :
Alzheimer's research & therapy [Alzheimers Res Ther] 2022 Jun 09; Vol. 14 (1), pp. 80. Date of Electronic Publication: 2022 Jun 09.
Typ publikacji :
Journal Article
MeSH Terms :
Alzheimer Disease*/pathology
Amyloidosis*
Animals ; Disease Models, Animal ; Disease Progression ; Humans ; Mice ; Neuroinflammatory Diseases ; Oxidative Stress ; Positron-Emission Tomography/methods ; Receptors, GABA/metabolism
Czasopismo naukowe
Tytuł :
Isogenic GAA-KO Murine Muscle Cell Lines Mimicking Severe Pompe Mutations as Preclinical Models for the Screening of Potential Gene Therapy Strategies.
Autorzy :
Aguilar-González A; GENYO, Centre for Genomics and Oncological Research: Pfizer, University of Granada, Andalusian Regional Government PTS Granada-Avenida de la Ilustración 114, 18016 Granada, Spain.; Department of Medicinal & Organic Chemistry and Excellence Research Unit of 'Chemistry Applied to Biomedicine and the Environment', Faculty of Pharmacy, University of Granada, Campus de Cartuja s/n, 18071 Granada, Spain.
González-Correa JE; GENYO, Centre for Genomics and Oncological Research: Pfizer, University of Granada, Andalusian Regional Government PTS Granada-Avenida de la Ilustración 114, 18016 Granada, Spain.
Barriocanal-Casado E; GENYO, Centre for Genomics and Oncological Research: Pfizer, University of Granada, Andalusian Regional Government PTS Granada-Avenida de la Ilustración 114, 18016 Granada, Spain.
Ramos-Hernández I; GENYO, Centre for Genomics and Oncological Research: Pfizer, University of Granada, Andalusian Regional Government PTS Granada-Avenida de la Ilustración 114, 18016 Granada, Spain.
Lerma-Juárez MA; Instituto de Investigación del Hospital Universitario La Paz, IdiPAZ, 28029 Madrid, Spain.
Greco S; GENYO, Centre for Genomics and Oncological Research: Pfizer, University of Granada, Andalusian Regional Government PTS Granada-Avenida de la Ilustración 114, 18016 Granada, Spain.
Rodríguez-Sevilla JJ; GENYO, Centre for Genomics and Oncological Research: Pfizer, University of Granada, Andalusian Regional Government PTS Granada-Avenida de la Ilustración 114, 18016 Granada, Spain.
Molina-Estévez FJ; GENYO, Centre for Genomics and Oncological Research: Pfizer, University of Granada, Andalusian Regional Government PTS Granada-Avenida de la Ilustración 114, 18016 Granada, Spain.; Fundación para la Investigación Biosanitaria de Andalucía Oriental-Alejandro Otero (FIBAO), 18012 Granada, Spain.
Montalvo-Romeral V; Généthon, Integrare Research Unit UMR_S951, INSERM, Université Paris-Saclay, Univ Evry, 91002 Evry, France.
Ronzitti G; Généthon, Integrare Research Unit UMR_S951, INSERM, Université Paris-Saclay, Univ Evry, 91002 Evry, France.
Sánchez-Martín RM; GENYO, Centre for Genomics and Oncological Research: Pfizer, University of Granada, Andalusian Regional Government PTS Granada-Avenida de la Ilustración 114, 18016 Granada, Spain.; Department of Medicinal & Organic Chemistry and Excellence Research Unit of 'Chemistry Applied to Biomedicine and the Environment', Faculty of Pharmacy, University of Granada, Campus de Cartuja s/n, 18071 Granada, Spain.
Martín F; GENYO, Centre for Genomics and Oncological Research: Pfizer, University of Granada, Andalusian Regional Government PTS Granada-Avenida de la Ilustración 114, 18016 Granada, Spain.; Departamento de Bioquímica y Biología Molecular 3 e Inmunología, Facultad de Medicina, Universidad de Granada, Avda. de la Investigación 11, 18071 Granada, Spain.
Muñoz P; GENYO, Centre for Genomics and Oncological Research: Pfizer, University of Granada, Andalusian Regional Government PTS Granada-Avenida de la Ilustración 114, 18016 Granada, Spain.; Departmento de Biología Celular, Facultad de Ciencias, Universidad de Granada, Campus Fuentenueva, 18071 Granada, Spain.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2022 Jun 04; Vol. 23 (11). Date of Electronic Publication: 2022 Jun 04.
Typ publikacji :
Journal Article
MeSH Terms :
Dependovirus*/genetics
Glycogen Storage Disease Type II*/genetics
Glycogen Storage Disease Type II*/therapy
Animals ; Cell Line ; Disease Models, Animal ; Genetic Therapy ; Genetic Vectors/genetics ; Humans ; Mice ; Mice, Knockout ; Muscle Cells/metabolism ; Muscle, Skeletal/metabolism ; Mutation ; alpha-Glucosidases/metabolism
Czasopismo naukowe
Tytuł :
Long-term Disease Behavior and Surgical Intervention Analysis in Hospitalized Patients With Crohn's Disease in China: A Retrospective Cohort Study.
Autorzy :
Bai X; Department of Gastroenterology, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, China.
Zhang H; Department of Gastroenterology, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, China.
Ruan G; Department of Gastroenterology, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, China.
Lv H; Department of Gastroenterology, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, China.
Li Y; Department of Gastroenterology, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, China.
Li J; Department of Gastroenterology, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, China.
Tan B; Department of Gastroenterology, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, China.
Zheng W; Department of Gastroenterology, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, China.
Jin M; Department of Gastroenterology, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, China.
Xu H; Department of Gastroenterology, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, China.
Yang H; Department of Gastroenterology, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, China.
Qian J; Department of Gastroenterology, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, China.
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Źródło :
Inflammatory bowel diseases [Inflamm Bowel Dis] 2022 Jun 02; Vol. 28 (Supplement_2), pp. S35-S41.
Typ publikacji :
Journal Article
MeSH Terms :
Crohn Disease*/complications
Crohn Disease*/drug therapy
Crohn Disease*/surgery
Adrenal Cortex Hormones/therapeutic use ; China/epidemiology ; Disease Progression ; Humans ; Prognosis ; Retrospective Studies
Czasopismo naukowe
Tytuł :
Disordered Decision Making: A Cognitive Framework for Apathy and Impulsivity in Huntington's Disease.
Autorzy :
Morris LA; Department of Medicine, University of Otago, Christchurch, New Zealand.; New Zealand Brain Research Institute, Christchurch, New Zealand.
O'Callaghan C; Brain and Mind Centre and School of Medical Sciences, Faculty of Medicine and Health, University of Sydney, Sydney, New South Wales, Australia.
Le Heron C; Department of Medicine, University of Otago, Christchurch, New Zealand.; New Zealand Brain Research Institute, Christchurch, New Zealand.; Department of Neurology, Canterbury District Health Board, Christchurch, New Zealand.
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Źródło :
Movement disorders : official journal of the Movement Disorder Society [Mov Disord] 2022 Jun; Vol. 37 (6), pp. 1149-1163. Date of Electronic Publication: 2022 May 02.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Apathy*/physiology
Huntington Disease*/genetics
Neurodegenerative Diseases*/complications
Parkinson Disease*/complications
Cognition ; Decision Making ; Disease Progression ; Humans ; Impulsive Behavior ; Male ; Quality of Life
Czasopismo naukowe
Tytuł :
PET Imaging of Cholinergic Neurotransmission in Neurodegenerative Disorders.
Autorzy :
Tiepolt S; Department of Nuclear Medicine, University of Leipzig, Leipzig, Germany; and.
Meyer PM; Department of Nuclear Medicine, University of Leipzig, Leipzig, Germany; and.
Patt M; Department of Nuclear Medicine, University of Leipzig, Leipzig, Germany; and.
Deuther-Conrad W; Helmholtz-Zentrum Dresden-Rossendorf, Research Site Leipzig, Leipzig, Germany.
Hesse S; Department of Nuclear Medicine, University of Leipzig, Leipzig, Germany; and.
Barthel H; Department of Nuclear Medicine, University of Leipzig, Leipzig, Germany; and.
Sabri O; Department of Nuclear Medicine, University of Leipzig, Leipzig, Germany; and .
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Źródło :
Journal of nuclear medicine : official publication, Society of Nuclear Medicine [J Nucl Med] 2022 Jun; Vol. 63 (Suppl 1), pp. 33S-44S.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Alzheimer Disease*
Lewy Body Disease*
Acetylcholine ; Cholinergic Agents ; Disease Progression ; Humans ; Positron-Emission Tomography/methods ; Synaptic Transmission
Czasopismo naukowe
Tytuł :
Diet in the Pathogenesis and Management of Crohn's Disease.
Autorzy :
Gu P; Division of Digestive and Liver Diseases, UT Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX 75390, USA.
Feagins LA; Department of Medicine, Center for Inflammatory Bowel Diseases, University of Texas at Austin, Dell Medical School, Health Discovery Building, Z0900 1601 Trinity Street, Building B, Austin, TX 78712, USA. Electronic address: .
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Źródło :
Gastroenterology clinics of North America [Gastroenterol Clin North Am] 2022 Jun; Vol. 51 (2), pp. 319-335. Date of Electronic Publication: 2022 Apr 22.
Typ publikacji :
Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms :
Colitis, Ulcerative*/therapy
Crohn Disease*/epidemiology
Crohn Disease*/etiology
Crohn Disease*/therapy
Diet/adverse effects ; Genetic Predisposition to Disease ; Humans ; Incidence
Czasopismo naukowe
Tytuł :
Dietary administration of D-chiro-inositol attenuates sex-specific metabolic imbalances in the 5xFAD mouse model of Alzheimer's disease.
Autorzy :
López-Gambero AJ; Instituto de investigación Biomédica de Málaga-IBIMA, 29010 Málaga, Spain; UGC Salud Mental, Hospital Regional Universitario de Málaga, 29010 Málaga, Spain; Universidad de Málaga, Andalucia Tech, Departamento de Biología Celular, Genética y Fisiología, Campus de Teatinos s/n, 29071 Málaga, Spain. Electronic address: .
Pacheco-Sánchez B; Instituto de investigación Biomédica de Málaga-IBIMA, 29010 Málaga, Spain. Electronic address: .
Rosell-Valle C; Instituto de investigación Biomédica de Málaga-IBIMA, 29010 Málaga, Spain. Electronic address: .
Medina-Vera D; Instituto de investigación Biomédica de Málaga-IBIMA, 29010 Málaga, Spain; Universidad de Málaga, Andalucia Tech, Departamento de Biología Celular, Genética y Fisiología, Campus de Teatinos s/n, 29071 Málaga, Spain; Universidad de Málaga, Andalucia Tech, Facultad de Medicina, Campus de Teatinos s/n, 29071 Málaga, Spain; UGC Corazón, Hospital Universitario Virgen de la Victoria, 29010 Málaga, Spain. Electronic address: .
Navarro JA; Instituto de investigación Biomédica de Málaga-IBIMA, 29010 Málaga, Spain; UGC Salud Mental, Hospital Regional Universitario de Málaga, 29010 Málaga, Spain; Universidad de Málaga, Andalucia Tech, Facultad de Medicina, Campus de Teatinos s/n, 29071 Málaga, Spain. Electronic address: juan_.
Fernández-Arjona MDM; Instituto de investigación Biomédica de Málaga-IBIMA, 29010 Málaga, Spain; UGC Salud Mental, Hospital Regional Universitario de Málaga, 29010 Málaga, Spain. Electronic address: .
de Ceglia M; Instituto de investigación Biomédica de Málaga-IBIMA, 29010 Málaga, Spain; UGC Salud Mental, Hospital Regional Universitario de Málaga, 29010 Málaga, Spain. Electronic address: .
Sanjuan C; EURONUTRA S.L, Parque Tecnológico de Andalucía, Campanillas, 29590, Spain. Electronic address: .
Simon V; University of Bordeaux, INSERM, Neurocentre Magendie, U1215, 33000 Bordeaux, France. Electronic address: .
Cota D; University of Bordeaux, INSERM, Neurocentre Magendie, U1215, 33000 Bordeaux, France. Electronic address: .
Rivera P; Instituto de investigación Biomédica de Málaga-IBIMA, 29010 Málaga, Spain; UGC Salud Mental, Hospital Regional Universitario de Málaga, 29010 Málaga, Spain. Electronic address: .
Rodríguez de Fonseca F; Instituto de investigación Biomédica de Málaga-IBIMA, 29010 Málaga, Spain; UGC Salud Mental, Hospital Regional Universitario de Málaga, 29010 Málaga, Spain. Electronic address: .
Suárez J; Instituto de investigación Biomédica de Málaga-IBIMA, 29010 Málaga, Spain; Universidad de Málaga, Andalucia Tech, Facultad de Medicina, Campus de Teatinos s/n, 29071 Málaga, Spain; Departamento de Anatomía Humana, Medicina Legal e Historia de la Ciencia, Universidad de Málaga, 29071 Málaga, Spain. Electronic address: .
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Źródło :
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2022 Jun; Vol. 150, pp. 112994. Date of Electronic Publication: 2022 Apr 26.
Typ publikacji :
Journal Article
MeSH Terms :
Alzheimer Disease*/drug therapy
Alzheimer Disease*/metabolism
Insulin Resistance*/physiology
Animals ; Disease Models, Animal ; Female ; Humans ; Inositol/pharmacology ; Inositol/therapeutic use ; Insulin/metabolism ; Male ; Mice ; Mice, Transgenic ; Weight Loss
Czasopismo naukowe
Tytuł :
Characterization of Moyamoya and Middle Cerebral Artery Diseases by Carotid Canal Diameter and RNF213 p.R4810K Genotype.
Autorzy :
Oichi Y; Department of Neurosurgery, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Mineharu Y; Department of Neurosurgery, Kyoto University Graduate School of Medicine, Kyoto, Japan; Comprehensive Stroke Center, Kobe City Medical Center General Hospital, Kobe, Japan; Department of Artificial Intelligence in Healthcare and Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan. Electronic address: .
Agawa Y; Department of Neurosurgery, Kyoto University Graduate School of Medicine, Kyoto, Japan; Department of Neurosurgery, Kokura Memorial Hospital, Kokura, Japan.
Morimoto T; Department of Neurosurgery, Kyoto University Graduate School of Medicine, Kyoto, Japan; Department of Neurosurgery, Amagasaki General Medical Center, Amagasaki, Japan.
Funaki T; Department of Neurosurgery, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Hitomi T; Department of Health and Environmental Sciences, Kyoto University Graduate School of Medicine, Kyoto, Japan; Department of Preventive Medicine, St. Marianna University School of Medicine, Kawasaki, Japan.
Kobayashi H; Department of Health and Environmental Sciences, Kyoto University Graduate School of Medicine, Kyoto, Japan; Department of Environmental and Molecular Medicine, Mie University Graduate School of Medicine, Tsu, Japan.
Todo K; Comprehensive Stroke Center, Kobe City Medical Center General Hospital, Kobe, Japan; Department of Neurology, Osaka University Graduate School of Medicine, Suita, Japan.
Tani S; Comprehensive Stroke Center, Kobe City Medical Center General Hospital, Kobe, Japan; Department of Neurosurgery, Tenri Hospital, Tenri, Japan.
Imamura H; Comprehensive Stroke Center, Kobe City Medical Center General Hospital, Kobe, Japan.
Yoshida K; Department of Neurosurgery, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Kataoka H; Department of Neurosurgery, Kyoto University Graduate School of Medicine, Kyoto, Japan; Department of Neurosurgery, National Cerebral and Cardiovascular Center, Suita, Japan.
Koizumi A; Department of Health and Environmental Sciences, Kyoto University Graduate School of Medicine, Kyoto, Japan; Social Health Medicine Welfare Laboratory, Kyoto-Hokenkai, Kyoto, Japan.
Sakai N; Comprehensive Stroke Center, Kobe City Medical Center General Hospital, Kobe, Japan.
Miyamoto S; Department of Neurosurgery, Kyoto University Graduate School of Medicine, Kyoto, Japan.
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Źródło :
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association [J Stroke Cerebrovasc Dis] 2022 Jun; Vol. 31 (6), pp. 106481. Date of Electronic Publication: 2022 Apr 15.
Typ publikacji :
Journal Article
MeSH Terms :
Adenosine Triphosphatases*/genetics
Moyamoya Disease*/diagnostic imaging
Moyamoya Disease*/genetics
Ubiquitin-Protein Ligases*/genetics
Adult ; Child ; Female ; Genetic Predisposition to Disease ; Genotype ; Humans ; Male ; Transcription Factors
SCR Disease Name :
Moyamoya disease 1
Czasopismo naukowe

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