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Wyszukujesz frazę ""Ihle, Michaela Angelika"" wg kryterium: Autor


Wyświetlanie 1-20 z 20
Tytuł :
Clinicopathological and molecular features of a large cohort of gastrointestinal stromal tumors (GISTs) and review of the literature: BRAF mutations in KIT/PDGFRA wild-type GISTs are rare events
Autorzy :
Huss, Sebastian
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Źródło :
In Human Pathology April 2017 62:206-214
Czasopismo naukowe
Tytuł :
EGFR T790M mutation testing of non-small cell lung cancer tissue and blood samples artificially spiked with circulating cell-free tumor DNA: results of a round robin trial
Autorzy :
Fassunke, Jana
Ihle, Michaela Angelika
Lenze, Dido
Lehmann, Annika
Hummel, Michael
Vollbrecht, Claudia
Penzel, Roland
Volckmar, Anna-Lena
Stenzinger, Albrecht
Endris, Volker
Jung, Andreas
Lehmann, Ulrich
Zeugner, Silke
Baretton, Gustavo
Kreipe, Hans
Schirmacher, Peter
Kirchner, Thomas
Dietel, Manfred
Büttner, Reinhard
Merkelbach-Bruse, Sabine
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Źródło :
Virchows Archiv: European Journal of Pathology. :1-12
Czasopismo naukowe
Tytuł :
Expression of cell cycle regulators and frequency of TP53 mutations in high risk gastrointestinal stromal tumors prior to adjuvant imatinib treatment.
Autorzy :
Ihle, Michaela Angelika
Huss, Sebastian
Jeske, Wiebke
Hartmann, Wolfgang
Merkelbach-Bruse, Sabine
Schildhaus, Hans-Ulrich
Büttner, Reinhard
Sihto, Harri
Sundby Hall, Kirsten
Eriksson, Mikael
Reichardt, Peter
Joensuu, Heikki
Wardelmann, Eva
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Źródło :
PLoS ONE. 2/16/2018, Vol. 13 Issue 2, p1-17. 17p.
Czasopismo naukowe
Tytuł :
Comparison of high resolution melting analysis, pyrosequencing, next generation sequencing and immunohistochemistry to conventional Sanger sequencing for the detection of p.V600E and non-p.V600E BRAF mutations.
Autorzy :
Ihle, Michaela Angelika michaela.ihle@uk-koeln.de
Fassunke, Jana
König, Katharina
Grünewald, Inga
Schlaak, Max
Kreuzberg, Nicole
Tietze, Lothar
Schildhaus, Hans- Ulrich
Büttner, Reinhard
Merkelbach-Bruse, Sabine
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Źródło :
BMC Cancer. 2014, Vol. 14 Issue 1, p1-25. 25p.
Czasopismo naukowe
Tytuł :
EGFR T790M mutation testing of non-small cell lung cancer tissue and blood samples artificially spiked with circulating cell-free tumor DNA: results of a round robin trial.
Autorzy :
Fassunke J; Institue of Pathology, University Hospital Cologne, Kerpener Strasse 62, 50924, Cologne, Germany. .
Ihle MA; Institue of Pathology, University Hospital Cologne, Kerpener Strasse 62, 50924, Cologne, Germany.
Lenze D; Institute of Pathology, Charité-University Hospital Berlin, Campus Mitte, Virchowweg 15, 10117, Berlin, Germany.
Lehmann A; Institute of Pathology, Charité-University Hospital Berlin, Campus Mitte, Virchowweg 15, 10117, Berlin, Germany.
Hummel M; Institute of Pathology, Charité-University Hospital Berlin, Campus Mitte, Virchowweg 15, 10117, Berlin, Germany.
Vollbrecht C; Institute of Pathology, Charité-University Hospital Berlin, Campus Mitte, Virchowweg 15, 10117, Berlin, Germany.
Penzel R; Institute of Pathology, University Hospital Heidelberg, Im Neuenheimer Feld 224, Heidelberg, Germany.
Volckmar AL; Institute of Pathology, University Hospital Heidelberg, Im Neuenheimer Feld 224, Heidelberg, Germany.
Stenzinger A; Institute of Pathology, University Hospital Heidelberg, Im Neuenheimer Feld 224, Heidelberg, Germany.
Endris V; Institute of Pathology, University Hospital Heidelberg, Im Neuenheimer Feld 224, Heidelberg, Germany.
Jung A; Pathologisches Institut of the Ludwig-Maximilinas-Universität München, Thalkirchnerstrasse 36, 80336, Munich, Germany.
Lehmann U; Institute of Pathology, Hannover Medical School, Carl-Neuberg-Strasse 1, 30625, Hannover, Germany.
Zeugner S; Institute of Pathology, University Hospital Dresden Carl Gustav Carus, Fetscherstrasse 74, 01307, Dresden, Germany.
Baretton G; Institute of Pathology, University Hospital Dresden Carl Gustav Carus, Fetscherstrasse 74, 01307, Dresden, Germany.
Kreipe H; Institute of Pathology, Hannover Medical School, Carl-Neuberg-Strasse 1, 30625, Hannover, Germany.
Schirmacher P; Institute of Pathology, University Hospital Heidelberg, Im Neuenheimer Feld 224, Heidelberg, Germany.
Kirchner T; Pathologisches Institut of the Ludwig-Maximilinas-Universität München, Thalkirchnerstrasse 36, 80336, Munich, Germany.
Dietel M; Institute of Pathology, Charité-University Hospital Berlin, Campus Mitte, Virchowweg 15, 10117, Berlin, Germany.
Büttner R; Institue of Pathology, University Hospital Cologne, Kerpener Strasse 62, 50924, Cologne, Germany.
Merkelbach-Bruse S; Institue of Pathology, University Hospital Cologne, Kerpener Strasse 62, 50924, Cologne, Germany.
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Źródło :
Virchows Archiv : an international journal of pathology [Virchows Arch] 2017 Oct; Vol. 471 (4), pp. 509-520. Date of Electronic Publication: 2017 Sep 08.
Typ publikacji :
Clinical Trial; Journal Article
MeSH Terms :
Quality Assurance, Health Care*
Circulating Tumor DNA/*analysis
DNA Mutational Analysis/*standards
ErbB Receptors/*analysis
Genotyping Techniques/*standards
Carcinoma, Non-Small-Cell Lung/blood ; Carcinoma, Non-Small-Cell Lung/genetics ; ErbB Receptors/genetics ; Germany ; Humans ; Lung Neoplasms/blood ; Lung Neoplasms/genetics
Czasopismo naukowe
Tytuł :
FGFR2 is overexpressed in myxoid liposarcoma and inhibition of FGFR signaling impairs tumor growth in vitro.
Autorzy :
Künstlinger H; Institute of Pathology, University Hospital Cologne, Cologne, Germany.
Fassunke J; Institute of Pathology, University Hospital Cologne, Cologne, Germany.
Schildhaus HU; Institute of Pathology, University Hospital Göttingen, Göttingen, Germany.
Brors B; Computational Oncology, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Heydt C; Institute of Pathology, University Hospital Cologne, Cologne, Germany.
Ihle MA; Institute of Pathology, University Hospital Cologne, Cologne, Germany.
Mechtersheimer G; Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany.
Wardelmann E; Gerhard-Domagk-Institute of Pathology, University Hospital Münster, Münster, Germany.
Büttner R; Institute of Pathology, University Hospital Cologne, Cologne, Germany.
Merkelbach-Bruse S; Institute of Pathology, University Hospital Cologne, Cologne, Germany.
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Źródło :
Oncotarget [Oncotarget] 2015 Aug 21; Vol. 6 (24), pp. 20215-30.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Liposarcoma, Myxoid/*metabolism
Receptor, Fibroblast Growth Factor, Type 2/*biosynthesis
Receptors, Fibroblast Growth Factor/*antagonists & inhibitors
Cell Line, Tumor ; Cell Movement/physiology ; Cell Proliferation/physiology ; Cohort Studies ; Gene Expression ; Humans ; Liposarcoma, Myxoid/drug therapy ; Liposarcoma, Myxoid/genetics ; Liposarcoma, Myxoid/pathology ; Microarray Analysis ; Pyrimidines/pharmacology ; Receptor, Fibroblast Growth Factor, Type 2/genetics ; Receptor, Fibroblast Growth Factor, Type 2/metabolism ; Receptors, Fibroblast Growth Factor/metabolism ; Signal Transduction/drug effects
Czasopismo naukowe
Tytuł :
Massively parallel sequencing fails to detect minor resistant subclones in tissue samples prior to tyrosine kinase inhibitor therapy.
Autorzy :
Heydt C; Institute of Pathology, University Hospital Cologne, Kerpener Str. 62, 50937, Cologne, Germany. .
Kumm N; Institute of Pathology, University Hospital Erlangen, Krankenhausstraße 8-10, 91054, Erlangen, Germany. .
Fassunke J; Institute of Pathology, University Hospital Cologne, Kerpener Str. 62, 50937, Cologne, Germany. .
Künstlinger H; Institute of Pathology, University Hospital Cologne, Kerpener Str. 62, 50937, Cologne, Germany. .
Ihle MA; Institute of Pathology, University Hospital Cologne, Kerpener Str. 62, 50937, Cologne, Germany. michaela.ihle@uk-koeln.de.
Scheel A; Institute of Pathology, University Hospital Cologne, Kerpener Str. 62, 50937, Cologne, Germany. .
Schildhaus HU; Institute of Pathology, University Hospital Göttingen, Robert-Koch-Strasse 40, 37075, Göttingen, Germany. .
Haller F; Institute of Pathology, University Hospital Erlangen, Krankenhausstraße 8-10, 91054, Erlangen, Germany. .
Büttner R; Institute of Pathology, University Hospital Cologne, Kerpener Str. 62, 50937, Cologne, Germany. .
Odenthal M; Institute of Pathology, University Hospital Cologne, Kerpener Str. 62, 50937, Cologne, Germany. .
Wardelmann E; Gerhard-Domagk-Institute of Pathology, University Hospital Münster, Albert-Schweitzer-Campus 1, Gebäude D17, 48149, Münster, Germany. .
Merkelbach-Bruse S; Institute of Pathology, University Hospital Cologne, Kerpener Str. 62, 50937, Cologne, Germany. .
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Źródło :
BMC cancer [BMC Cancer] 2015 Apr 15; Vol. 15, pp. 291. Date of Electronic Publication: 2015 Apr 15.
Typ publikacji :
Journal Article
MeSH Terms :
Drug Resistance, Neoplasm/*genetics
Gastrointestinal Neoplasms/*genetics
Gastrointestinal Stromal Tumors/*genetics
High-Throughput Nucleotide Sequencing/*methods
Protein Kinase Inhibitors/*therapeutic use
Adult ; Aged ; Aged, 80 and over ; Cohort Studies ; Drug Resistance, Neoplasm/drug effects ; Female ; Gastrointestinal Neoplasms/diagnosis ; Gastrointestinal Neoplasms/drug therapy ; Gastrointestinal Stromal Tumors/diagnosis ; Gastrointestinal Stromal Tumors/drug therapy ; Humans ; Male ; Middle Aged ; Protein Kinase Inhibitors/pharmacology ; Retrospective Studies
Czasopismo naukowe
Tytuł :
Comparison of pre-analytical FFPE sample preparation methods and their impact on massively parallel sequencing in routine diagnostics.
Autorzy :
Heydt C; Institute of Pathology, University Hospital Cologne, Cologne, Germany.
Fassunke J; Institute of Pathology, University Hospital Cologne, Cologne, Germany.
Künstlinger H; Institute of Pathology, University Hospital Cologne, Cologne, Germany.
Ihle MA; Institute of Pathology, University Hospital Cologne, Cologne, Germany.
König K; Institute of Pathology, University Hospital Cologne, Cologne, Germany.
Heukamp LC; Institute of Pathology, University Hospital Cologne, Cologne, Germany.
Schildhaus HU; Institute of Pathology, University Hospital Göttingen, Göttingen, Germany.
Odenthal M; Institute of Pathology, University Hospital Cologne, Cologne, Germany.
Büttner R; Institute of Pathology, University Hospital Cologne, Cologne, Germany.
Merkelbach-Bruse S; Institute of Pathology, University Hospital Cologne, Cologne, Germany.
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Źródło :
PloS one [PLoS One] 2014 Aug 08; Vol. 9 (8), pp. e104566. Date of Electronic Publication: 2014 Aug 08 (Print Publication: 2014).
Typ publikacji :
Comparative Study; Journal Article
MeSH Terms :
High-Throughput Nucleotide Sequencing/*methods
Paraffin Embedding/*methods
Tissue Fixation/*methods
DNA/genetics ; DNA/isolation & purification ; DNA Mutational Analysis/methods ; Formaldehyde/chemistry ; Humans ; Sequence Analysis, DNA/methods
Czasopismo naukowe
Tytuł :
Comparison of high resolution melting analysis, pyrosequencing, next generation sequencing and immunohistochemistry to conventional Sanger sequencing for the detection of p.V600E and non-p.V600E BRAF mutations.
Autorzy :
Ihle MA; Institute of Pathology, University of Cologne, Medical Centre, Cologne, Germany. michaela.ihle@uk-koeln.de.
Fassunke J
König K
Grünewald I
Schlaak M
Kreuzberg N
Tietze L
Schildhaus HU
Büttner R
Merkelbach-Bruse S
Pokaż więcej
Źródło :
BMC cancer [BMC Cancer] 2014 Jan 10; Vol. 14, pp. 13. Date of Electronic Publication: 2014 Jan 10.
Typ publikacji :
Comparative Study; Journal Article
MeSH Terms :
Biomarkers, Tumor*/analysis
Biomarkers, Tumor*/genetics
High-Throughput Nucleotide Sequencing*
Immunohistochemistry*
Mutation*
Polymerase Chain Reaction*
Proto-Oncogene Proteins B-raf*/analysis
Proto-Oncogene Proteins B-raf*/antagonists & inhibitors
Proto-Oncogene Proteins B-raf*/genetics
DNA Mutational Analysis/*methods
Antineoplastic Agents/therapeutic use ; Humans ; Indoles/therapeutic use ; Melanoma/drug therapy ; Melanoma/enzymology ; Melanoma/genetics ; Molecular Targeted Therapy ; Paraffin Embedding ; Patient Selection ; Precision Medicine ; Predictive Value of Tests ; Protein Kinase Inhibitors/therapeutic use ; Skin Neoplasms/drug therapy ; Skin Neoplasms/enzymology ; Skin Neoplasms/genetics ; Sulfonamides/therapeutic use ; Tissue Fixation ; Vemurafenib
Czasopismo naukowe
    Wyświetlanie 1-20 z 20

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