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Wyszukujesz frazę ""Lewis X Antigen"" wg kryterium: Temat


Tytuł :
Complementary Role of GlcNAc6ST2 and GlcNAc6ST3 in Synthesis of CL40-Reactive Sialylated and Sulfated Glycans in the Mouse Pleural Mesothelium.
Autorzy :
Takeda-Uchimura Y; Unité de Glycobiologie Structurale et Fonctionnelle, UMR 8576 of the Centre National de la Recherche Scientifique, University of Lille, Villeneuve d'Ascq, F-59655 Lille, France.
Ikezaki M; Department of Biochemistry, School of Medicine, Wakayama Medical University, Wakayama 641-8509, Japan.
Akama TO; Department of Pharmacology, Kansai Medical University, Osaka 570-8506, Japan.
Nishioka K; Department of Obstetrics and Gynecology, School of Medicine, Wakayama Medical University, Wakayama 641-8509, Japan.
Ihara Y; Department of Biochemistry, School of Medicine, Wakayama Medical University, Wakayama 641-8509, Japan.
Allain F; Unité de Glycobiologie Structurale et Fonctionnelle, UMR 8576 of the Centre National de la Recherche Scientifique, University of Lille, Villeneuve d'Ascq, F-59655 Lille, France.
Nishitsuji K; Department of Biochemistry, School of Medicine, Wakayama Medical University, Wakayama 641-8509, Japan.
Uchimura K; Unité de Glycobiologie Structurale et Fonctionnelle, UMR 8576 of the Centre National de la Recherche Scientifique, University of Lille, Villeneuve d'Ascq, F-59655 Lille, France.
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Źródło :
Molecules (Basel, Switzerland) [Molecules] 2022 Jul 16; Vol. 27 (14). Date of Electronic Publication: 2022 Jul 16.
Typ publikacji :
Journal Article
MeSH Terms :
Lewis X Antigen*/metabolism
Sulfates*
Animals ; Epithelium/metabolism ; Epitopes/metabolism ; Mice ; Oligosaccharides/metabolism ; Pleura/metabolism ; Polysaccharides/metabolism ; Sialyl Lewis X Antigen
Czasopismo naukowe
Tytuł :
An embeddable molecular code for Lewis X modification through interaction with fucosyltransferase 9.
Autorzy :
Saito T; Graduate School of Pharmaceutical Sciences, Nagoya City University, 3-1 Tanabe-dori, Mizuho-ku, Nagoya, 467-8603, Japan.; Institute for Molecular Science, National Institutes of Natural Sciences, 5-1 Higashiyama, Myodaiji-cho, Okazaki, 444-8787, Japan.
Yagi H; Graduate School of Pharmaceutical Sciences, Nagoya City University, 3-1 Tanabe-dori, Mizuho-ku, Nagoya, 467-8603, Japan.; Exploratory Research Center on Life and Living Systems (ExCELLS), National Institutes of Natural Sciences, 5-1 Higashiyama, Myodaiji-cho, Okazaki, 444-8787, Japan.
Kuo CW; Institute of Biological Chemistry, Academia Sinica, 128, Academia Road Sec. 2, Nankang, Taipei, 115, Taiwan.
Khoo KH; Exploratory Research Center on Life and Living Systems (ExCELLS), National Institutes of Natural Sciences, 5-1 Higashiyama, Myodaiji-cho, Okazaki, 444-8787, Japan.; Institute of Biological Chemistry, Academia Sinica, 128, Academia Road Sec. 2, Nankang, Taipei, 115, Taiwan.
Kato K; Graduate School of Pharmaceutical Sciences, Nagoya City University, 3-1 Tanabe-dori, Mizuho-ku, Nagoya, 467-8603, Japan. .; Institute for Molecular Science, National Institutes of Natural Sciences, 5-1 Higashiyama, Myodaiji-cho, Okazaki, 444-8787, Japan. .; Exploratory Research Center on Life and Living Systems (ExCELLS), National Institutes of Natural Sciences, 5-1 Higashiyama, Myodaiji-cho, Okazaki, 444-8787, Japan. .
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Źródło :
Communications biology [Commun Biol] 2022 Jul 13; Vol. 5 (1), pp. 676. Date of Electronic Publication: 2022 Jul 13.
Typ publikacji :
Journal Article
MeSH Terms :
Fucosyltransferases*/genetics
Lewis X Antigen*/genetics
Lewis X Antigen*/metabolism
Glycoproteins/metabolism ; Glycosylation ; Polysaccharides/metabolism
Czasopismo naukowe
Tytuł :
Circulating SSEA-1 stem cell-mediated tissue repair in allergic airway inflammation.
Autorzy :
Chiu CJ; Graduate Institute of Clinical Medicine, College of Medicine, National Taiwan University, Taipei, Taiwan.
Liao CC; Graduate Institute of Immunology, College of Medicine, National Taiwan University, Taipei, Taiwan.
Hsu YH; Institute of Clinical Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Chiang BL; Graduate Institute of Clinical Medicine, College of Medicine, National Taiwan University, Taipei, Taiwan. .; Department of Paediatrics, National Taiwan University Hospital, Taipei, Taiwan. .; Department of Medical Research, National Taiwan University Hospital, No. 7 Chung-Shan South Road, Taipei, 100, Taiwan. .
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Źródło :
Cellular and molecular life sciences : CMLS [Cell Mol Life Sci] 2022 Jun 07; Vol. 79 (7), pp. 347. Date of Electronic Publication: 2022 Jun 07.
Typ publikacji :
Journal Article
MeSH Terms :
Asthma*
Lewis X Antigen*/metabolism
Airway Remodeling ; Allergens/metabolism ; Allergens/pharmacology ; Animals ; Bronchoalveolar Lavage Fluid ; Disease Models, Animal ; Inflammation/metabolism ; Lung/metabolism ; Mice ; Mice, Inbred BALB C ; Ovalbumin/metabolism ; Stem Cells/metabolism
Czasopismo naukowe
Tytuł :
Insights into Selectin Inhibitor Design from Endogenous Isomeric Ligands of SLe .
Autorzy :
Hu Z; Cardiac Arrhythmia Center, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100037, China.
Bie L; Hubei Key Laboratory of Agricultural Bioinformatics, College of Informatics, Huazhong Agricultural University, Wuhan, Hubei 430070, China.
Gao J; Hubei Key Laboratory of Agricultural Bioinformatics, College of Informatics, Huazhong Agricultural University, Wuhan, Hubei 430070, China.
Wang X; Hubei Key Laboratory of Agricultural Bioinformatics, College of Informatics, Huazhong Agricultural University, Wuhan, Hubei 430070, China.
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Źródło :
Journal of chemical information and modeling [J Chem Inf Model] 2021 Dec 27; Vol. 61 (12), pp. 6085-6093. Date of Electronic Publication: 2021 Dec 14.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Lectins*/antagonists & inhibitors
Oligosaccharides*/chemistry
Selectins*
Sialyl Lewis X Antigen*/chemistry
Ligands
Czasopismo naukowe
Tytuł :
The Sd Synthase B4GALNT2 Reduces Malignancy and Stemness in Colon Cancer Cell Lines Independently of Sialyl Lewis X Inhibition.
Autorzy :
Pucci M; Department of Experimental, Diagnostic and Specialty Medicine (DIMES), General Pathology Building, University of Bologna, Via San Giacomo 14, 40126 Bologna, Italy.
Gomes Ferreira I; Department of Experimental, Diagnostic and Specialty Medicine (DIMES), General Pathology Building, University of Bologna, Via San Giacomo 14, 40126 Bologna, Italy.
Malagolini N; Department of Experimental, Diagnostic and Specialty Medicine (DIMES), General Pathology Building, University of Bologna, Via San Giacomo 14, 40126 Bologna, Italy.
Ferracin M; Department of Experimental, Diagnostic and Specialty Medicine (DIMES), General Pathology Building, University of Bologna, Via San Giacomo 14, 40126 Bologna, Italy.
Dall'Olio F; Department of Experimental, Diagnostic and Specialty Medicine (DIMES), General Pathology Building, University of Bologna, Via San Giacomo 14, 40126 Bologna, Italy.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2020 Sep 08; Vol. 21 (18). Date of Electronic Publication: 2020 Sep 08.
Typ publikacji :
Journal Article
MeSH Terms :
Colonic Neoplasms/*metabolism
N-Acetylgalactosaminyltransferases/*metabolism
Sialyl Lewis X Antigen/*metabolism
Cell Line ; Cell Line, Tumor ; Colonic Neoplasms/genetics ; Fucosyltransferases/genetics ; Fucosyltransferases/metabolism ; Glycosyltransferases/metabolism ; Humans ; Lewis X Antigen/metabolism ; N-Acetylgalactosaminyltransferases/genetics ; Neoplastic Stem Cells/metabolism ; Neoplastic Stem Cells/physiology ; Oligosaccharides/genetics ; Oligosaccharides/immunology ; Oligosaccharides/metabolism ; Sialyl Lewis X Antigen/physiology ; Transfection ; Tumor Cells, Cultured
Czasopismo naukowe
Tytuł :
Polyethylene glycol-coated ultrasmall superparamagnetic iron oxide nanoparticles-coupled sialyl Lewis X nanotheranostic platform for nasopharyngeal carcinoma imaging and photothermal therapy.
Autorzy :
Liu Q; Department of Radiology, Guangxi Medical University Cancer Hospital, Nanning, 530021, China.
Liu L; Department of Radiology, Guangxi Medical University Cancer Hospital, Nanning, 530021, China.
Mo C; Department of Radiology, Guangxi Medical University Cancer Hospital, Nanning, 530021, China.
Zhou X; Department of Radiology, Guangxi Medical University Cancer Hospital, Nanning, 530021, China.
Chen D; Department of Radiology, Guangxi Medical University Cancer Hospital, Nanning, 530021, China.
He Y; Department of Radiology, Guangxi Medical University Cancer Hospital, Nanning, 530021, China.
He H; Department of Radiology, Guangxi Medical University Cancer Hospital, Nanning, 530021, China.
Kang W; Department of Radiology, Guangxi Medical University Cancer Hospital, Nanning, 530021, China.
Zhao Y; Department of Chemistry and Biochemistry, Jackson State University, Jackson, MS, 39217, USA.
Jin G; Department of Radiology, Guangxi Medical University Cancer Hospital, Nanning, 530021, China. .
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Źródło :
Journal of nanobiotechnology [J Nanobiotechnology] 2021 Jun 08; Vol. 19 (1), pp. 171. Date of Electronic Publication: 2021 Jun 08.
Typ publikacji :
Journal Article
MeSH Terms :
Dextrans/*chemistry
Magnetite Nanoparticles/*chemistry
Nanoparticles/*chemistry
Nasopharyngeal Carcinoma/*drug therapy
Photothermal Therapy/*methods
Polyethylene Glycols/*chemistry
Sialyl Lewis X Antigen/*pharmacology
Theranostic Nanomedicine/*methods
Animals ; Cell Line, Tumor ; Magnetic Iron Oxide Nanoparticles ; Magnetic Resonance Imaging/methods ; Mice ; Mice, Inbred BALB C ; Mice, Nude ; Nasopharyngeal Carcinoma/diagnostic imaging ; Nasopharyngeal Neoplasms ; Phototherapy ; Sialyl Lewis X Antigen/chemistry
Czasopismo naukowe
Tytuł :
Expression of the Carbohydrate Lewis Antigen, Sialyl Lewis A, Sialyl Lewis X, Lewis X, and Lewis Y in the Placental Villi of Patients With Unexplained Miscarriages.
Autorzy :
Ma Z; Department of Obstetrics and Gynaecology, University Hospital LMU Munich, Munich, Germany.
Yang H; Department of Obstetrics and Gynaecology, University Hospital LMU Munich, Munich, Germany.
Peng L; Department of Obstetrics and Gynaecology, University Hospital LMU Munich, Munich, Germany.
Kuhn C; Department of Obstetrics and Gynaecology, University Hospital Augsburg, Augsburg, Germany.
Chelariu-Raicu A; Department of Obstetrics and Gynaecology, University Hospital LMU Munich, Munich, Germany.
Mahner S; Department of Obstetrics and Gynaecology, University Hospital LMU Munich, Munich, Germany.
Jeschke U; Department of Obstetrics and Gynaecology, University Hospital LMU Munich, Munich, Germany.; Department of Obstetrics and Gynaecology, University Hospital Augsburg, Augsburg, Germany.
von Schönfeldt V; Department of Obstetrics and Gynaecology, University Hospital LMU Munich, Munich, Germany.
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Źródło :
Frontiers in immunology [Front Immunol] 2021 May 31; Vol. 12, pp. 679424. Date of Electronic Publication: 2021 May 31 (Print Publication: 2021).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Biomarkers*
Gene Expression*
Abortion, Spontaneous/*etiology
Abortion, Spontaneous/*metabolism
Chorionic Villi/*metabolism
Lewis X Antigen/*genetics
Abortion, Spontaneous/diagnosis ; Carbohydrate Metabolism ; Carbohydrates ; Disease Susceptibility ; Female ; Gestational Age ; Humans ; Immunohistochemistry ; Lewis X Antigen/metabolism ; Metabolic Networks and Pathways ; Pregnancy
Czasopismo naukowe
Tytuł :
Glycan analysis of human neutrophil granules implicates a maturation-dependent glycosylation machinery.
Autorzy :
Venkatakrishnan V; Department of Rheumatology and Inflammation Research, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden .
Dieckmann R; Department of Rheumatology and Inflammation Research, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Loke I; Department of Molecular Sciences, Macquarie University, Sydney, Australia.; Cordlife Group Limited, Singapore.
Tjondro HC; Department of Molecular Sciences, Macquarie University, Sydney, Australia.
Chatterjee S; Department of Molecular Sciences, Macquarie University, Sydney, Australia.
Bylund J; Department of Oral Microbiology and Immunology, Institute of Odontology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Thaysen-Andersen M; Department of Molecular Sciences, Macquarie University, Sydney, Australia.; Biomolecular Discovery Research Centre, Macquarie University, Sydney, Australia.
Karlsson NG; Department of Medical Chemistry and Cell Biology, Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Karlsson-Bengtsson A; Department of Rheumatology and Inflammation Research, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.; Department of Biology and Biological Engineering, Chalmers University of Technology, Gothenburg, Sweden.
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Źródło :
The Journal of biological chemistry [J Biol Chem] 2020 Sep 04; Vol. 295 (36), pp. 12648-12660. Date of Electronic Publication: 2020 Jul 14.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cytoplasmic Granules/*metabolism
Lewis X Antigen/*metabolism
Neutrophils/*metabolism
Polysaccharides/*metabolism
Sialyl Lewis X Antigen/*metabolism
Glycosylation ; Humans ; Lewis X Antigen/analysis ; Polysaccharides/analysis ; Sialyl Lewis X Antigen/analysis
Czasopismo naukowe
Tytuł :
Tumor cell E-selectin ligands determine partialefficacy of bortezomib on spontaneous lung metastasis formation of solid human tumors in vivo.
Autorzy :
Lange T; Institute of Anatomy and Experimental Morphology, University Cancer Center Hamburg, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany. Electronic address: .
Valentiner U; Institute of Anatomy and Experimental Morphology, University Cancer Center Hamburg, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Wicklein D; Institute of Anatomy and Experimental Morphology, University Cancer Center Hamburg, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Maar H; Institute of Anatomy and Experimental Morphology, University Cancer Center Hamburg, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Labitzky V; Institute of Anatomy and Experimental Morphology, University Cancer Center Hamburg, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Ahlers AK; Institute of Anatomy and Experimental Morphology, University Cancer Center Hamburg, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Starzonek S; Institute of Anatomy and Experimental Morphology, University Cancer Center Hamburg, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Genduso S; Institute of Anatomy and Experimental Morphology, University Cancer Center Hamburg, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Staffeldt L; Institute of Anatomy and Experimental Morphology, University Cancer Center Hamburg, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Pahlow C; Institute of Anatomy and Experimental Morphology, University Cancer Center Hamburg, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Dück AM; Institute of Anatomy and Experimental Morphology, University Cancer Center Hamburg, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Stürken C; Institute of Anatomy and Experimental Morphology, University Cancer Center Hamburg, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Baranowsky A; Department of Trauma and Orthopedic Surgery, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Bauer AT; Department of Dermatology, University Cancer Center Hamburg, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Bulk E; Institute of Physiology II, University of Münster, 48149 Münster, Germany.
Schwab A; Institute of Physiology II, University of Münster, 48149 Münster, Germany.
Riecken K; Research Department Cell and Gene Therapy, Department of Stem Cell Transplantation, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Börnchen C; Department of Anesthesiology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Kiefmann R; Department of Anesthesiology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Abraham V; Pulmonary, Allergy and Critical Care Division, Department of Medicine, School of Medicine, University of Pennsylvania, Philadelphia, PA 19104-4539, USA.
DeLisser HM; Pulmonary, Allergy and Critical Care Division, Department of Medicine, School of Medicine, University of Pennsylvania, Philadelphia, PA 19104-4539, USA.
Gemoll T; Section for Translational Surgical Oncology and Biobanking, Department of Surgery, University of Lübeck and University Medical Center Schleswig Holstein, Campus Lübeck, 23538 Lübeck, Germany.
Habermann JK; Section for Translational Surgical Oncology and Biobanking, Department of Surgery, University of Lübeck and University Medical Center Schleswig Holstein, Campus Lübeck, 23538 Lübeck, Germany.
Block A; Department of Oncology, University Cancer Center Hamburg, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Pantel K; Institute of Tumor Biology, University Cancer Center Hamburg, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Schumacher U; Institute of Anatomy and Experimental Morphology, University Cancer Center Hamburg, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
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Źródło :
Molecular therapy : the journal of the American Society of Gene Therapy [Mol Ther] 2022 Apr 06; Vol. 30 (4), pp. 1536-1552. Date of Electronic Publication: 2022 Jan 12.
Typ publikacji :
Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, Non-U.S. Gov't
MeSH Terms :
E-Selectin*/genetics
E-Selectin*/metabolism
Lung Neoplasms*/drug therapy
Lung Neoplasms*/pathology
Animals ; Bortezomib/pharmacology ; CA-19-9 Antigen/pharmacology ; Cell Adhesion ; Humans ; Ligands ; Mice ; Neoplasm Metastasis ; Oligosaccharides ; Sialyl Lewis X Antigen
Czasopismo naukowe
Tytuł :
Microfibril associated protein 4 (MFAP4) is a carrier of the tumor associated carbohydrate sialyl-Lewis x (sLe ) in pancreatic adenocarcinoma.
Autorzy :
Guerrero PE; Biochemistry and Molecular Biology Unit, Department of Biology, University of Girona, 17003 Girona, Spain.
Duran A; Biochemistry and Molecular Biology Unit, Department of Biology, University of Girona, 17003 Girona, Spain.
Ortiz MR; Pathology Department, Josep Trueta University Hospital, 17007 Girona, Spain.
Castro E; Hepato-biliary and Pancreatic Surgery Unit, Josep Trueta University Hospital, 17007 Girona, Spain.
Garcia-Velasco A; Institut Catala d'Oncologia (ICO). Josep Trueta University Hospital, 17007, Girona, Spain.
Llop E; Biochemistry and Molecular Biology Unit, Department of Biology, University of Girona, 17003 Girona, Spain.. Electronic address: .
Peracaula R; Biochemistry and Molecular Biology Unit, Department of Biology, University of Girona, 17003 Girona, Spain.. Electronic address: .
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Źródło :
Journal of proteomics [J Proteomics] 2021 Jan 16; Vol. 231, pp. 104004. Date of Electronic Publication: 2020 Oct 07.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Adenocarcinoma*/diagnosis
Carrier Proteins*
Extracellular Matrix Proteins*
Glycoproteins*/metabolism
Pancreatic Neoplasms*/diagnosis
Sialyl Lewis X Antigen*
Biomarkers, Tumor ; Humans ; Microfibrils/metabolism
Czasopismo naukowe
Tytuł :
Specific Norovirus Interaction with Lewis x and Lewis a on Human Intestinal Inflammatory Mucosa during Refractory Inflammatory Bowel Disease.
Autorzy :
Tarris G; Department of Pathology, University Hospital of Dijon, Dijon, France.
de Rougemont A; National Reference Centre for Gastroenteritis Viruses, Laboratory of Virology, University Hospital of Dijon, Dijon, France.; UMR PAM A 02.102 Procédés Alimentaires et Microbiologiques, Université de Bourgogne Franche-Comté/AgroSup Dijon, Dijon, France.
Estienney M; National Reference Centre for Gastroenteritis Viruses, Laboratory of Virology, University Hospital of Dijon, Dijon, France.; UMR PAM A 02.102 Procédés Alimentaires et Microbiologiques, Université de Bourgogne Franche-Comté/AgroSup Dijon, Dijon, France.
Charkaoui M; Department of Gastroenterology and Hepatology, University Hospital of Dijon, Dijon, France.
Mouillot T; Department of Gastroenterology and Hepatology, University Hospital of Dijon, Dijon, France.
Bonnotte B; Department of Internal Medicine and Clinical Immunology, University Hospital of Dijon, Dijon, France.; Univ. Bourgogne Franche-Comté, INSERM, EFS BFC, UMR1098, Interactions Hôte-Greffon-Tumeur/Ingénierie Cellulaire et Génique, Dijon, France.
Michiels C; Department of Gastroenterology and Hepatology, University Hospital of Dijon, Dijon, France.
Martin L; Department of Pathology, University Hospital of Dijon, Dijon, France .; Univ. Bourgogne Franche-Comté, INSERM, EFS BFC, UMR1098, Interactions Hôte-Greffon-Tumeur/Ingénierie Cellulaire et Génique, Dijon, France.
Belliot G; National Reference Centre for Gastroenteritis Viruses, Laboratory of Virology, University Hospital of Dijon, Dijon, France .; UMR PAM A 02.102 Procédés Alimentaires et Microbiologiques, Université de Bourgogne Franche-Comté/AgroSup Dijon, Dijon, France.
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Źródło :
MSphere [mSphere] 2021 Jan 13; Vol. 6 (1). Date of Electronic Publication: 2021 Jan 13.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
CA-19-9 Antigen/*metabolism
Gastrointestinal Tract/*microbiology
Inflammatory Bowel Diseases/*microbiology
Intestinal Mucosa/*microbiology
Lewis X Antigen/*metabolism
Norovirus/*metabolism
Adult ; CA-19-9 Antigen/genetics ; Female ; Gastrointestinal Tract/anatomy & histology ; Humans ; Immunohistochemistry ; Lewis X Antigen/genetics ; Male ; Middle Aged ; Severity of Illness Index ; Young Adult
Czasopismo naukowe
Tytuł :
Molecular and structural basis for Lewis glycan recognition by a cancer-targeting antibody.
Autorzy :
Soliman C; School of Science, RMIT University, Melbourne, Victoria, Australia.
Guy AJ; School of Science, RMIT University, Melbourne, Victoria, Australia.
Chua JX; Scancell Limited, University of Nottingham Biodiscovery Institute, University Park, Nottingham, U.K.
Vankemmelbeke M; Scancell Limited, University of Nottingham Biodiscovery Institute, University Park, Nottingham, U.K.
McIntosh RS; Division of Cancer and Stem Cells, School of Medicine, University of Nottingham Biodiscovery Institute, University Park, Nottingham, U.K.
Eastwood S; School of Science, RMIT University, Melbourne, Victoria, Australia.
Truong VK; School of Science, RMIT University, Melbourne, Victoria, Australia.
Elbourne A; School of Science, RMIT University, Melbourne, Victoria, Australia.
Spendlove I; Division of Cancer and Stem Cells, School of Medicine, University of Nottingham Biodiscovery Institute, University Park, Nottingham, U.K.
Durrant LG; Scancell Limited, University of Nottingham Biodiscovery Institute, University Park, Nottingham, U.K.; Division of Cancer and Stem Cells, School of Medicine, University of Nottingham Biodiscovery Institute, University Park, Nottingham, U.K.
Ramsland PA; School of Science, RMIT University, Melbourne, Victoria, Australia.; Department of Immunology, Central Clinical School, Monash University, Melbourne, Victoria, Australia.; Department of Surgery Austin Health, University of Melbourne, Melbourne, Victoria, Australia.
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Źródło :
The Biochemical journal [Biochem J] 2020 Sep 18; Vol. 477 (17), pp. 3219-3235.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antibodies, Monoclonal, Murine-Derived*/chemistry
Antibodies, Monoclonal, Murine-Derived*/immunology
Antineoplastic Agents, Immunological*/chemistry
Antineoplastic Agents, Immunological*/immunology
Immunoglobulin Fab Fragments*/chemistry
Immunoglobulin Fab Fragments*/immunology
Lewis Blood Group Antigens*/chemistry
Lewis Blood Group Antigens*/immunology
Lewis X Antigen*/chemistry
Lewis X Antigen*/immunology
Molecular Docking Simulation*
Neoplasms*/chemistry
Neoplasms*/immunology
Oligosaccharides*/chemistry
Oligosaccharides*/immunology
Animals ; Cell Line, Tumor ; Humans ; Mice
Czasopismo naukowe
Tytuł :
A Potent Mimetic of the Siglec-8 Ligand 6'-Sulfo-Sialyl Lewis .
Autorzy :
Kroezen BS; Molecular Pharmacy Group Department of Pharmaceutical Sciences, University of Basel, Klingelbergstrasse 50, 4056, Basel, Switzerland.
Conti G; Molecular Pharmacy Group Department of Pharmaceutical Sciences, University of Basel, Klingelbergstrasse 50, 4056, Basel, Switzerland.
Girardi B; Molecular Pharmacy Group Department of Pharmaceutical Sciences, University of Basel, Klingelbergstrasse 50, 4056, Basel, Switzerland.
Cramer J; Molecular Pharmacy Group Department of Pharmaceutical Sciences, University of Basel, Klingelbergstrasse 50, 4056, Basel, Switzerland.
Jiang X; Molecular Pharmacy Group Department of Pharmaceutical Sciences, University of Basel, Klingelbergstrasse 50, 4056, Basel, Switzerland.
Rabbani S; Molecular Pharmacy Group Department of Pharmaceutical Sciences, University of Basel, Klingelbergstrasse 50, 4056, Basel, Switzerland.
Müller J; Molecular Pharmacy Group Department of Pharmaceutical Sciences, University of Basel, Klingelbergstrasse 50, 4056, Basel, Switzerland.
Kokot M; Molecular Pharmacy Group Department of Pharmaceutical Sciences, University of Basel, Klingelbergstrasse 50, 4056, Basel, Switzerland.
Luisoni E; Molecular Pharmacy Group Department of Pharmaceutical Sciences, University of Basel, Klingelbergstrasse 50, 4056, Basel, Switzerland.
Ricklin D; Molecular Pharmacy Group Department of Pharmaceutical Sciences, University of Basel, Klingelbergstrasse 50, 4056, Basel, Switzerland.
Schwardt O; Molecular Pharmacy Group Department of Pharmaceutical Sciences, University of Basel, Klingelbergstrasse 50, 4056, Basel, Switzerland.
Ernst B; Molecular Pharmacy Group Department of Pharmaceutical Sciences, University of Basel, Klingelbergstrasse 50, 4056, Basel, Switzerland.
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Źródło :
ChemMedChem [ChemMedChem] 2020 Sep 16; Vol. 15 (18), pp. 1706-1719. Date of Electronic Publication: 2020 Aug 31.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Lectins/*antagonists & inhibitors
Oligosaccharides/*pharmacology
Sialyl Lewis X Antigen/*analogs & derivatives
Antigens, CD/metabolism ; Antigens, Differentiation, B-Lymphocyte/metabolism ; Humans ; Lectins/metabolism ; Ligands ; Molecular Structure ; Oligosaccharides/chemical synthesis ; Oligosaccharides/chemistry ; Sialyl Lewis X Antigen/chemistry ; Sialyl Lewis X Antigen/pharmacology ; Thermodynamics
Czasopismo naukowe
Tytuł :
Phenotyping clonal populations of glioma stem cell reveals a high degree of plasticity in response to changes of microenvironment.
Autorzy :
Innes JA; Department of Neurodegenerative Disease, Queen Square Institute of Neurology, University College London, Queen Square, London, WC1N 3BG, UK.
Lowe AS; Department of Neurodegenerative Disease, Queen Square Institute of Neurology, University College London, Queen Square, London, WC1N 3BG, UK.
Fonseca R; Department of Neurodegenerative Disease, Queen Square Institute of Neurology, University College London, Queen Square, London, WC1N 3BG, UK.
Aley N; Department of Neurodegenerative Disease, Queen Square Institute of Neurology, University College London, Queen Square, London, WC1N 3BG, UK.
El-Hassan T; Department of Neurodegenerative Disease, Queen Square Institute of Neurology, University College London, Queen Square, London, WC1N 3BG, UK.
Constantinou M; Blizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University London, London, E1 2AT, UK.
Lau J; Department of Neurodegenerative Disease, Queen Square Institute of Neurology, University College London, Queen Square, London, WC1N 3BG, UK.
Eddaoudi A; Zayed Centre for Research Into Rare Disease in Children, UCL Great Ormond Street Institute of Child Health, University College London, London, WC1N 1DZ, UK.
Marino S; Blizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University London, London, E1 2AT, UK.
Brandner S; Department of Neurodegenerative Disease, Queen Square Institute of Neurology, University College London, Queen Square, London, WC1N 3BG, UK. .
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Źródło :
Laboratory investigation; a journal of technical methods and pathology [Lab Invest] 2022 Feb; Vol. 102 (2), pp. 172-184. Date of Electronic Publication: 2021 Nov 15.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antigens, CD/*immunology
Brain Neoplasms/*immunology
Glioma/*immunology
Neoplastic Stem Cells/*immunology
Tumor Microenvironment/*immunology
AC133 Antigen/immunology ; AC133 Antigen/metabolism ; Antigens, CD/metabolism ; Biomarkers, Tumor/immunology ; Biomarkers, Tumor/metabolism ; Brain Neoplasms/metabolism ; Brain Neoplasms/pathology ; Cell Line, Tumor ; Cells, Cultured ; Clone Cells/immunology ; Clone Cells/metabolism ; Flow Cytometry ; Glioma/metabolism ; Glioma/pathology ; Humans ; Hyaluronan Receptors/immunology ; Hyaluronan Receptors/metabolism ; Immunophenotyping ; Lewis X Antigen/immunology ; Lewis X Antigen/metabolism ; Microscopy, Confocal ; Neoplastic Stem Cells/classification ; Neoplastic Stem Cells/metabolism
Czasopismo naukowe
Tytuł :
sLeX Expression Delineates Distinct Functional Subsets of Human Blood Central and Effector Memory T Cells.
Autorzy :
Silva M; Harvard Skin Disease Research Center, Department of Dermatology, Brigham and Women's Hospital, Boston, MA 02115.; Program of Excellence in Glycosciences, Harvard Medical School, Boston, MA 02115.
Martin KC; Harvard Skin Disease Research Center, Department of Dermatology, Brigham and Women's Hospital, Boston, MA 02115.; Program of Excellence in Glycosciences, Harvard Medical School, Boston, MA 02115.; Department of Translational Medicine and Translational Glycobiology Institute, Herbert Wertheim College of Medicine, Florida International University, Miami, FL 33199; and.
Mondal N; Harvard Skin Disease Research Center, Department of Dermatology, Brigham and Women's Hospital, Boston, MA 02115.; Program of Excellence in Glycosciences, Harvard Medical School, Boston, MA 02115.
Sackstein R; Harvard Skin Disease Research Center, Department of Dermatology, Brigham and Women's Hospital, Boston, MA 02115; .; Program of Excellence in Glycosciences, Harvard Medical School, Boston, MA 02115.; Department of Translational Medicine and Translational Glycobiology Institute, Herbert Wertheim College of Medicine, Florida International University, Miami, FL 33199; and.; Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115.
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Źródło :
Journal of immunology (Baltimore, Md. : 1950) [J Immunol] 2020 Oct 01; Vol. 205 (7), pp. 1920-1932. Date of Electronic Publication: 2020 Aug 31.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Sialyl Lewis X Antigen/*metabolism
T-Lymphocyte Subsets/*immunology
T-Lymphocytes, Regulatory/*immunology
Cell Differentiation ; Cell Lineage ; Cells, Cultured ; Central Tolerance ; Cytotoxicity, Immunologic ; GATA3 Transcription Factor/metabolism ; Gene Expression Regulation ; Humans ; Immune Tolerance ; Immunologic Memory ; Lymphocyte Activation ; Nuclear Receptor Subfamily 1, Group F, Member 3/genetics ; Nuclear Receptor Subfamily 1, Group F, Member 3/metabolism ; Peripheral Tolerance ; Programmed Cell Death 1 Receptor/metabolism ; Sialyl Lewis X Antigen/genetics
Czasopismo naukowe
Tytuł :
Distinct human α(1,3)-fucosyltransferases drive Lewis-X/sialyl Lewis-X assembly in human cells.
Autorzy :
Mondal N; Department of Dermatology and Harvard Skin Disease Research Center, Boston, Massachusetts 02115; Program of Excellence in Glycosciences, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115.
Dykstra B; Department of Dermatology and Harvard Skin Disease Research Center, Boston, Massachusetts 02115; Program of Excellence in Glycosciences, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115.
Lee J; Program in Cellular and Molecular Medicine, Division of Hematology/Oncology, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts 02115; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, Massachusetts 02138.
Ashline DJ; Program of Excellence in Glycosciences, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115; Department of Molecular, Cellular, and Biomedical Sciences, The Glycomics Center, University of New Hampshire, Durham, New Hampshire 03828.
Reinhold VN; Program of Excellence in Glycosciences, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115; Department of Molecular, Cellular, and Biomedical Sciences, The Glycomics Center, University of New Hampshire, Durham, New Hampshire 03828.
Rossi DJ; Program in Cellular and Molecular Medicine, Division of Hematology/Oncology, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts 02115; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, Massachusetts 02138.
Sackstein R; Department of Dermatology and Harvard Skin Disease Research Center, Boston, Massachusetts 02115; Program of Excellence in Glycosciences, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115; Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115. Electronic address: .
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Źródło :
The Journal of biological chemistry [J Biol Chem] 2018 May 11; Vol. 293 (19), pp. 7300-7314. Date of Electronic Publication: 2018 Mar 28.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Fucosyltransferases/*metabolism
Isoenzymes/*metabolism
Lewis X Antigen/*metabolism
Mesenchymal Stem Cells/*enzymology
Amino Sugars/metabolism ; Flow Cytometry ; Fucosyltransferases/genetics ; Glycoconjugates/metabolism ; Glycomics ; Humans ; Isoenzymes/genetics ; Lewis X Antigen/genetics ; Mass Spectrometry ; Mesenchymal Stem Cells/immunology ; RNA, Messenger/genetics ; Sialyl Lewis X Antigen
Czasopismo naukowe
Tytuł :
An Introduction to the Relationship Between Lewis x and Malignancy Mainly Related to Breast Cancer and Head Neck Squamous Cell Carcinoma (HNSCC).
Autorzy :
Croce MV; Centro de Investigaciones Inmunológicas Básicas y Aplicadas (CINIBA), Facultad de Ciencias Médicas, Universidad Nacional de La Plata, La Plata, Argentina.
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Źródło :
Cancer investigation [Cancer Invest] 2022 Feb; Vol. 40 (2), pp. 173-183. Date of Electronic Publication: 2021 Dec 15.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Breast Neoplasms/*immunology
Head and Neck Neoplasms/*immunology
Lewis X Antigen/*metabolism
Squamous Cell Carcinoma of Head and Neck/*immunology
Biomarkers, Tumor/metabolism ; Female ; Gene Expression Regulation, Neoplastic ; Glycosylation ; Humans ; Survival Analysis
Czasopismo naukowe
Tytuł :
RNA Sequencing in COVID-19 patients identifies neutrophil activation biomarkers as a promising diagnostic platform for infections.
Autorzy :
Wargodsky R; Department of Medicine, Division of Genomic Medicine, The George Washington University Medical Center, Washington, DC, United States of America.
Dela Cruz P; Department Anesthesiology and Critical Care Medicine, The George Washington University Medical Center, Washington, DC, United States of America.
LaFleur J; Department of Emergency Medicine, The George Washington University Medical Center, Washington, DC, United States of America.
Yamane D; Department Anesthesiology and Critical Care Medicine, The George Washington University Medical Center, Washington, DC, United States of America.; Department of Emergency Medicine, The George Washington University Medical Center, Washington, DC, United States of America.
Kim JS; Department Anesthesiology and Critical Care Medicine, The George Washington University Medical Center, Washington, DC, United States of America.
Benjenk I; Department Anesthesiology and Critical Care Medicine, The George Washington University Medical Center, Washington, DC, United States of America.
Heinz E; Department Anesthesiology and Critical Care Medicine, The George Washington University Medical Center, Washington, DC, United States of America.
Irondi OO; Department Anesthesiology and Critical Care Medicine, The George Washington University Medical Center, Washington, DC, United States of America.
Farrar K; Department Anesthesiology and Critical Care Medicine, The George Washington University Medical Center, Washington, DC, United States of America.
Toma I; Department of Medicine, Division of Genomic Medicine, The George Washington University Medical Center, Washington, DC, United States of America.; Department of Clinical Research and Leadership The George Washington University Medical Center, Washington, DC, United States of America.; True Bearing Diagnostics, Washington, DC, United States of America.
Jordan T; Department of Medicine, Division of Genomic Medicine, The George Washington University Medical Center, Washington, DC, United States of America.
Goldman J; Department of Medicine, Division of Genomic Medicine, The George Washington University Medical Center, Washington, DC, United States of America.
McCaffrey TA; Department of Medicine, Division of Genomic Medicine, The George Washington University Medical Center, Washington, DC, United States of America.; Department of Clinical Research and Leadership The George Washington University Medical Center, Washington, DC, United States of America.; True Bearing Diagnostics, Washington, DC, United States of America.; Department of Microbiology, Immunology, and Tropical Medicine, The George Washington University Medical Center, Washington, DC, United States of America.
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Źródło :
PloS one [PLoS One] 2022 Jan 26; Vol. 17 (1), pp. e0261679. Date of Electronic Publication: 2022 Jan 26 (Print Publication: 2022).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Biomarkers/*blood
COVID-19/*diagnosis
Neutrophils/*metabolism
SARS-CoV-2/*genetics
Adult ; COVID-19/pathology ; COVID-19/virology ; Female ; Humans ; Intensive Care Units ; Lewis X Antigen/metabolism ; Male ; Middle Aged ; Neutrophil Activation ; Neutrophils/cytology ; Neutrophils/immunology ; Pancreatic Elastase/blood ; RNA, Viral/chemistry ; RNA, Viral/metabolism ; Receptors, Antigen, T-Cell/genetics ; SARS-CoV-2/isolation & purification ; Sensitivity and Specificity ; Sequence Analysis, RNA ; Severity of Illness Index ; alpha-Defensins/genetics
Czasopismo naukowe
Tytuł :
Chemoenzymatic Synthesis of Sialyl Sulfo-Oligosaccharides as Potent Siglec-8 Ligands via Transglycosylation Catalyzed by Keratanase II.
Autorzy :
Yuge S; Department of Material Chemistry, Graduate School of Engineering, Kyoto University, Kyoto 615-8510, Japan.
Tateishi A; Department of Material Chemistry, Graduate School of Engineering, Kyoto University, Kyoto 615-8510, Japan.
Numata K; Department of Material Chemistry, Graduate School of Engineering, Kyoto University, Kyoto 615-8510, Japan.
Ohmae M; Department of Material Chemistry, Graduate School of Engineering, Kyoto University, Kyoto 615-8510, Japan.
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Źródło :
Biomacromolecules [Biomacromolecules] 2022 Jan 10; Vol. 23 (1), pp. 316-325. Date of Electronic Publication: 2021 Dec 16.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Oligosaccharides*/chemical synthesis
Oligosaccharides*/chemistry
Sialic Acid Binding Immunoglobulin-like Lectins*
Acetylglucosaminidase/*metabolism
Carbohydrate Sequence ; Catalysis ; Ligands ; Sialyl Lewis X Antigen
Czasopismo naukowe
Tytuł :
B4GALNT2 Controls Sd Antigen Biosynthesis in Healthy and Cancer Human Colon.
Autorzy :
Groux-Degroote S; Univ. Lille, CNRS, UMR 8576, UGSF, Unité de Glycobiologie Structurale et Fonctionnelle, 59000, Lille, France.
Vicogne D; Univ. Lille, CNRS, UMR 8576, UGSF, Unité de Glycobiologie Structurale et Fonctionnelle, 59000, Lille, France.
Cogez V; Univ. Lille, CNRS, UMR 8576, UGSF, Unité de Glycobiologie Structurale et Fonctionnelle, 59000, Lille, France.
Schulz C; Univ. Lille, CNRS, UMR 8576, UGSF, Unité de Glycobiologie Structurale et Fonctionnelle, 59000, Lille, France.
Harduin-Lepers A; Univ. Lille, CNRS, UMR 8576, UGSF, Unité de Glycobiologie Structurale et Fonctionnelle, 59000, Lille, France.
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Źródło :
Chembiochem : a European journal of chemical biology [Chembiochem] 2021 Dec 10; Vol. 22 (24), pp. 3381-3390. Date of Electronic Publication: 2021 Sep 14.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Colon/*metabolism
Colonic Neoplasms/*metabolism
N-Acetylgalactosaminyltransferases/*metabolism
Oligosaccharides/*biosynthesis
Sialyl Lewis X Antigen/*biosynthesis
Colonic Neoplasms/diagnosis ; Humans ; Prognosis
Czasopismo naukowe

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