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Tytuł :
Potassium channels and epilepsy.
Autorzy :
Gao K; Department of Pediatrics, Peking University First Hospital, Beijing, China.; Beijing Key Laboratory of Molecular Diagnosis and Study on Pediatric Genetic Diseases, Beijing, China.; Children Epilepsy Center, Peking University First Hospital, Beijing, China.; Key Laboratory for Neuroscience, Ministry of Education/National Health and Family Planning Commission, Peking University, Beijing, China.
Lin Z; Department of Neurology, Affiliated Children's Hospital of Capital Institute of Pediatrics, Beijing, China.
Wen S; Department of Pediatrics, Peking University First Hospital, Beijing, China.; Beijing Key Laboratory of Molecular Diagnosis and Study on Pediatric Genetic Diseases, Beijing, China.; Children Epilepsy Center, Peking University First Hospital, Beijing, China.
Jiang Y; Department of Pediatrics, Peking University First Hospital, Beijing, China.; Beijing Key Laboratory of Molecular Diagnosis and Study on Pediatric Genetic Diseases, Beijing, China.; Children Epilepsy Center, Peking University First Hospital, Beijing, China.; Key Laboratory for Neuroscience, Ministry of Education/National Health and Family Planning Commission, Peking University, Beijing, China.; Center of Epilepsy, Beijing Institute for Brain Disorders, Beijing, China.
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Źródło :
Acta neurologica Scandinavica [Acta Neurol Scand] 2022 Dec; Vol. 146 (6), pp. 699-707. Date of Electronic Publication: 2022 Oct 12.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Potassium Channels*/genetics
Epilepsy*/diagnosis
Epilepsy*/genetics
Humans ; KCNQ3 Potassium Channel/genetics ; KCNQ2 Potassium Channel/genetics ; Mutation/genetics ; Shaw Potassium Channels/genetics ; Potassium Channels, Sodium-Activated/genetics ; Nerve Tissue Proteins/genetics
Czasopismo naukowe
Tytuł :
Ouabain-Induced Changes in the Expression of Voltage-Gated Potassium Channels in Epithelial Cells Depend on Cell-Cell Contacts.
Autorzy :
Cereijido M; Department of Physiology, Biophysics and Neurosciences, CINVESTAV-IPN, CDMX 07360, Mexico.
Jimenez L; Department of Physiology, Biophysics and Neurosciences, CINVESTAV-IPN, CDMX 07360, Mexico.
Hinojosa L; Department of Physiology, Biophysics and Neurosciences, CINVESTAV-IPN, CDMX 07360, Mexico.
Castillo A; Department of Physiology, Biophysics and Neurosciences, CINVESTAV-IPN, CDMX 07360, Mexico.
Martínez-Rendon J; Department of Physiology, Biophysics and Neurosciences, CINVESTAV-IPN, CDMX 07360, Mexico.; Molecular Medicine Laboratory, Unidad Academica de Medicina Humana y C.S, Campus UAZ Siglo XXI-L1, Universidad Autónoma de Zacatecas, Zacatecas 98160, Mexico.
Ponce A; Department of Physiology, Biophysics and Neurosciences, CINVESTAV-IPN, CDMX 07360, Mexico.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2022 Oct 31; Vol. 23 (21). Date of Electronic Publication: 2022 Oct 31.
Typ publikacji :
Journal Article
MeSH Terms :
Ouabain*/pharmacology
Potassium Channels, Voltage-Gated*
Animals ; Potassium/metabolism ; Potassium Channels/metabolism ; Sodium-Potassium-Exchanging ATPase/metabolism ; Epithelial Cells/metabolism ; Mammals/metabolism
Czasopismo naukowe
Tytuł :
Voltage-sensor movements in the Eag Kv channel under an applied electric field.
Autorzy :
Mandala VS; Laboratory of Molecular Neurobiology and Biophysics, The Rockefeller University, New York, NY, 10065.; HHMI, The Rockefeller University, New York, NY, 10065.
MacKinnon R; Laboratory of Molecular Neurobiology and Biophysics, The Rockefeller University, New York, NY, 10065.; HHMI, The Rockefeller University, New York, NY, 10065.
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Źródło :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2022 Nov 16; Vol. 119 (46), pp. e2214151119. Date of Electronic Publication: 2022 Nov 07.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Ion Channel Gating*/physiology
Potassium Channels, Voltage-Gated*/metabolism
Animals ; Cryoelectron Microscopy ; Lipid Bilayers/chemistry ; Potassium Channels ; Mammals/metabolism
Czasopismo naukowe
Tytuł :
Structure-activity relationship studies in a new series of 2-amino-N-phenylacetamide inhibitors of Slack potassium channels.
Autorzy :
Qunies AM; Department of Pharmaceutical Sciences, UNT System College of Pharmacy, University of North Texas Health Science Center, Fort Worth, TX, USA; Graduate School of Biomedical Sciences, University of North Texas Health Science Center, Fort Worth, TX, USA.
Mishra NM; Department of Pharmaceutical Sciences, UNT System College of Pharmacy, University of North Texas Health Science Center, Fort Worth, TX, USA.
Spitznagel BD; Department of Pharmacology, Vanderbilt University, Nashville, TN 37232, USA.
Du Y; Department of Pharmacology, Vanderbilt University, Nashville, TN 37232, USA; Vanderbilt Institute of Chemical Biology, Vanderbilt University, Nashville, TN 37232, USA.
Acuña VS; Department of Pharmaceutical Sciences, UNT System College of Pharmacy, University of North Texas Health Science Center, Fort Worth, TX, USA.
David Weaver C; Department of Pharmacology, Vanderbilt University, Nashville, TN 37232, USA; Vanderbilt Institute of Chemical Biology, Vanderbilt University, Nashville, TN 37232, USA.
Emmitte KA; Department of Pharmaceutical Sciences, UNT System College of Pharmacy, University of North Texas Health Science Center, Fort Worth, TX, USA. Electronic address: .
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Źródło :
Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2022 Nov 15; Vol. 76, pp. 129013. Date of Electronic Publication: 2022 Sep 29.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Potassium Channels*
Thallium*
Humans ; Potassium Channels, Sodium-Activated ; HEK293 Cells ; Nerve Tissue Proteins/metabolism ; Structure-Activity Relationship
Czasopismo naukowe
Tytuł :
Modulation of cardiac voltage-activated K currents by glypican 1 heparan sulfate proteoglycan.
Autorzy :
Souza DS; Department of Anesthesiology, College of Medicine, University of Arizona, Tucson, AZ 85724, USA.
Chignalia AZ; Department of Anesthesiology, College of Medicine, University of Arizona, Tucson, AZ 85724, USA; Department of Physiology, College of Medicine University of Arizona, Tucson, AZ 85724, USA; Department of Pharmacology and Toxicology, College of Pharmacy, University of Arizona, Tucson, AZ 85724, USA.
Carvalho-de-Souza JL; Department of Anesthesiology, College of Medicine, University of Arizona, Tucson, AZ 85724, USA; Department of Physiology, College of Medicine University of Arizona, Tucson, AZ 85724, USA; Department of Ophthalmology and Visual Sciences, College of Medicine, University of Arizona, Tucson, AZ 85724, USA; BIO5 Institute, University of Arizona, Tucson, AZ 85724, USA. Electronic address: .
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Źródło :
Life sciences [Life Sci] 2022 Nov 01; Vol. 308, pp. 120916. Date of Electronic Publication: 2022 Aug 29.
Typ publikacji :
Journal Article
MeSH Terms :
Heparan Sulfate Proteoglycans*/metabolism
Potassium Channels, Voltage-Gated*/genetics
Action Potentials/physiology ; Animals ; Arrhythmias, Cardiac/metabolism ; Glycosylphosphatidylinositols ; Glypicans/genetics ; KCNQ1 Potassium Channel ; Mice ; Myocytes, Cardiac/metabolism ; Potassium Channels/metabolism
Czasopismo naukowe
Tytuł :
Inhibition of platelet aggregation by activation of platelet intermediate conductance Ca -activated potassium channels.
Autorzy :
Back V; Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, Alberta, Canada.
Asgari A; Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, Alberta, Canada.
Franczak A; Department of Pharmacology, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada.
Saito M; Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, Alberta, Canada.
Castaneda Zaragoza D; Department of Pharmacology, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada.
Sandow SL; Biomedical Sciences, University of the Sunshine Coast, Sydney, Queensland, Australia.; Department of Physiology, University of New South Wales, Sydney, Queensland, Australia.
Plane F; Department of Pharmacology, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada.; Cardiovascular Research Centre, University of Alberta, Edmonton, Alberta, Canada.
Jurasz P; Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, Alberta, Canada.; Department of Pharmacology, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada.; Cardiovascular Research Centre, University of Alberta, Edmonton, Alberta, Canada.; Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada.
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Źródło :
Journal of thrombosis and haemostasis : JTH [J Thromb Haemost] 2022 Nov; Vol. 20 (11), pp. 2587-2600. Date of Electronic Publication: 2022 Aug 07.
Typ publikacji :
Journal Article
MeSH Terms :
Intermediate-Conductance Calcium-Activated Potassium Channels*/pharmacology
Endothelial Cells*/metabolism
Humans ; Nitric Oxide/metabolism ; Potassium Channels/pharmacology ; Platelet Aggregation ; Calcium/metabolism ; Phosphatidylserines ; Platelet Aggregation Inhibitors/pharmacology ; Integrins
Czasopismo naukowe
Tytuł :
Guillain-Barré-like syndrome: an uncommon feature of CASPR2 and LGI1 autoimmunity.
Autorzy :
Tan X; Department of Neurology, Shengjing Hospital of China Medical University, 39 Hua Xiang Road, Shenyang, 110022, Liaoning, People's Republic of China.
Liu Y; Department of Neurology, Shengjing Hospital of China Medical University, 39 Hua Xiang Road, Shenyang, 110022, Liaoning, People's Republic of China.
Wu X; Department of Neurology, Shengjing Hospital of China Medical University, 39 Hua Xiang Road, Shenyang, 110022, Liaoning, People's Republic of China.
Guo Y; Department of Neurology, Shengjing Hospital of China Medical University, 39 Hua Xiang Road, Shenyang, 110022, Liaoning, People's Republic of China. .
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Źródło :
Journal of neurology [J Neurol] 2022 Nov; Vol. 269 (11), pp. 5893-5900. Date of Electronic Publication: 2022 Jul 03.
Typ publikacji :
Case Reports; Journal Article
MeSH Terms :
Glioma*
Guillain-Barre Syndrome*
Potassium Channels, Voltage-Gated*
Autoantibodies ; Autoimmunity ; Contactins ; Humans ; Intracellular Signaling Peptides and Proteins ; Leucine ; Membrane Proteins ; Nerve Tissue Proteins ; Shaker Superfamily of Potassium Channels
Czasopismo naukowe
Tytuł :
Purification and membrane interactions of human KCNQ1 100-370 potassium ion channel.
Autorzy :
Dixit G; Department of Chemistry and Biochemistry, Miami University, 651 E. High Street, Oxford, OH 45056, USA; Cell, Molecular and Structural Biology Program, Department of Chemistry & Biochemistry, Miami University, Oxford, OH 45056, USA.
Stowe RB; Department of Chemistry and Biochemistry, Miami University, 651 E. High Street, Oxford, OH 45056, USA.
Bates A; Department of Chemistry and Biochemistry, Miami University, 651 E. High Street, Oxford, OH 45056, USA.
Jaycox CK; Department of Chemistry and Biochemistry, Miami University, 651 E. High Street, Oxford, OH 45056, USA.
Escobar JR; Department of Chemistry and Biochemistry, Miami University, 651 E. High Street, Oxford, OH 45056, USA; Cell, Molecular and Structural Biology Program, Department of Chemistry & Biochemistry, Miami University, Oxford, OH 45056, USA.
Harding BD; Department of Chemistry and Biochemistry, Miami University, 651 E. High Street, Oxford, OH 45056, USA.
Drew DL Jr; Department of Chemistry and Biochemistry, Miami University, 651 E. High Street, Oxford, OH 45056, USA.
New CP; Department of Chemistry and Biochemistry, Miami University, 651 E. High Street, Oxford, OH 45056, USA; Cell, Molecular and Structural Biology Program, Department of Chemistry & Biochemistry, Miami University, Oxford, OH 45056, USA.
Sahu ID; Department of Chemistry and Biochemistry, Miami University, 651 E. High Street, Oxford, OH 45056, USA.
Edelmann RE; Center for Advanced Microscopy and Imaging, Miami University, Oxford, OH 45056, USA.
Dabney-Smith C; Department of Chemistry and Biochemistry, Miami University, 651 E. High Street, Oxford, OH 45056, USA; Cell, Molecular and Structural Biology Program, Department of Chemistry & Biochemistry, Miami University, Oxford, OH 45056, USA.
Sanders CR; Department of Biochemistry and Center for Structural Biology, Vanderbilt University, Nashville, TN 37240, USA.
Lorigan GA; Department of Chemistry and Biochemistry, Miami University, 651 E. High Street, Oxford, OH 45056, USA; Cell, Molecular and Structural Biology Program, Department of Chemistry & Biochemistry, Miami University, Oxford, OH 45056, USA. Electronic address: .
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Źródło :
Biochimica et biophysica acta. Biomembranes [Biochim Biophys Acta Biomembr] 2022 Nov 01; Vol. 1864 (11), pp. 184010. Date of Electronic Publication: 2022 Jul 21.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Long QT Syndrome*
Potassium Channels, Voltage-Gated*/metabolism
Humans ; KCNQ1 Potassium Channel/metabolism ; Potassium/metabolism ; Potassium Channels ; Tandem Mass Spectrometry
Czasopismo naukowe
Tytuł :
The Ion Channel Gene KCNAB2 Is Associated with Poor Prognosis and Loss of Immune Infiltration in Lung Adenocarcinoma.
Autorzy :
Lyu Y; Thoracic Surgery Laboratory, Xuzhou Medical University, 84 West Huaihai Road, Xuzhou 221006, China.; Department of Thoracic Surgery, Affiliated Hospital of Xuzhou Medical University, 99 West Huaihai Road, Xuzhou 221006, China.
Wang Q; Thoracic Surgery Laboratory, Xuzhou Medical University, 84 West Huaihai Road, Xuzhou 221006, China.; Department of Thoracic Surgery, Affiliated Hospital of Xuzhou Medical University, 99 West Huaihai Road, Xuzhou 221006, China.
Liang J; Thoracic Surgery Laboratory, Xuzhou Medical University, 84 West Huaihai Road, Xuzhou 221006, China.; Department of Thoracic Surgery, Affiliated Hospital of Xuzhou Medical University, 99 West Huaihai Road, Xuzhou 221006, China.
Zhang L; Thoracic Surgery Laboratory, Xuzhou Medical University, 84 West Huaihai Road, Xuzhou 221006, China.; Department of Thoracic Surgery, Affiliated Hospital of Xuzhou Medical University, 99 West Huaihai Road, Xuzhou 221006, China.
Zhang H; Thoracic Surgery Laboratory, Xuzhou Medical University, 84 West Huaihai Road, Xuzhou 221006, China.; Department of Thoracic Surgery, Affiliated Hospital of Xuzhou Medical University, 99 West Huaihai Road, Xuzhou 221006, China.
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Źródło :
Cells [Cells] 2022 Oct 31; Vol. 11 (21). Date of Electronic Publication: 2022 Oct 31.
Typ publikacji :
Journal Article
MeSH Terms :
Adenocarcinoma of Lung*/immunology
Adenocarcinoma of Lung*/pathology
Shaker Superfamily of Potassium Channels*/genetics
Humans ; Gene Expression Regulation, Neoplastic ; Lung Neoplasms/immunology ; Lung Neoplasms/pathology ; Potassium Channels, Voltage-Gated ; Tumor Microenvironment/genetics ; Tumor Microenvironment/immunology ; Prognosis
Czasopismo naukowe
Tytuł :
[Association study between the KCNE family gene polymorphisms of potassium channel gene and the susceptibility of atrial fibrillation].
Autorzy :
Qin M; Department of Cardiology, Putuo Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai 200062, China.
Tao JR; Department of Cardiology, Putuo Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai 200062, China.
Liu ZJ; Department of Cardiology, Putuo Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai 200062, China.
Hu WY; Department of Cardiology, Putuo Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai 200062, China.
Yan PY; Department of Cardiology, Putuo Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai 200062, China.
Wang R; Department of Cardiology, Putuo Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai 200062, China.
Zhang Y; Department of Cardiology, Putuo Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai 200062, China.
Xu GJ; Department of Cardiology, Putuo Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai 200062, China.
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Źródło :
Zhonghua yi xue za zhi [Zhonghua Yi Xue Za Zhi] 2022 Oct 18; Vol. 102 (38), pp. 3026-3032.
Typ publikacji :
Journal Article
MeSH Terms :
Atrial Fibrillation*/genetics
Potassium Channels, Voltage-Gated*/genetics
Case-Control Studies ; China ; Genetic Predisposition to Disease ; Humans ; Male ; Polymorphism, Genetic ; Polymorphism, Single Nucleotide ; Potassium Channels/genetics
Czasopismo naukowe
Tytuł :
Investigation of novel de novo KCNC2 variants causing severe developmental and early-onset epileptic encephalopathy.
Autorzy :
Li L; Surgery Division, Epilepsy Center, Shenzhen Children's Hospital, Shenzhen, Guangdong 518038, China.
Liu Z; The Brain Cognition and Brain Disease Institute (BCBDI), Shenzhen Institute of Advanced Technology (SIAT), Chinese Academy of Sciences (CAS), Shenzhen-Hong Kong Institute of Brain Science-Shenzhen Fundamental Research Institutions, Shenzhen, Guangdong 518055, China.
Yang H; The Brain Cognition and Brain Disease Institute (BCBDI), Shenzhen Institute of Advanced Technology (SIAT), Chinese Academy of Sciences (CAS), Shenzhen-Hong Kong Institute of Brain Science-Shenzhen Fundamental Research Institutions, Shenzhen, Guangdong 518055, China; Guangdong Provincial Key Laboratory of Brain Connectome and Behavior, CAS Center for Excellence in Brain Science and Intelligence Technology, Shenzhen, Guangdong 518055, China; University of Chinese Academy of Sciences, Beijing 100049, China.
Li Y; University of Chinese Academy of Sciences, Beijing 100049, China; State Key Laboratory of Brain and Cognitive Science, Institute of Biophysics, CAS, Beijing 100101, China.
Zeng Q; Department of Neurology, Shenzhen Children's Hospital, Shenzhen, Guangdong 518038, China.
Chen L; Department of Neurology, Shenzhen Children's Hospital, Shenzhen, Guangdong 518038, China.
Liu Y; Department of Neurology, Shenzhen Children's Hospital, Shenzhen, Guangdong 518038, China.
Chen Y; Surgery Division, Epilepsy Center, Shenzhen Children's Hospital, Shenzhen, Guangdong 518038, China.
Zhu F; Surgery Division, Epilepsy Center, Shenzhen Children's Hospital, Shenzhen, Guangdong 518038, China.
Cao D; Surgery Division, Epilepsy Center, Shenzhen Children's Hospital, Shenzhen, Guangdong 518038, China; Department of Neurology, Shenzhen Children's Hospital, Shenzhen, Guangdong 518038, China.
Hu J; Department of Pediatrics, Fujian Medical University Union Hospital, Fuzhou, Fujian 350001, China. Electronic address: .
Shen X; The Brain Cognition and Brain Disease Institute (BCBDI), Shenzhen Institute of Advanced Technology (SIAT), Chinese Academy of Sciences (CAS), Shenzhen-Hong Kong Institute of Brain Science-Shenzhen Fundamental Research Institutions, Shenzhen, Guangdong 518055, China. Electronic address: .
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Źródło :
Seizure [Seizure] 2022 Oct; Vol. 101, pp. 218-224. Date of Electronic Publication: 2022 Sep 05.
Typ publikacji :
Journal Article
MeSH Terms :
Brain Diseases*
Potassium Channels, Voltage-Gated*/pharmacology
Action Potentials/genetics ; Animals ; HEK293 Cells ; Humans ; Mammals ; Patch-Clamp Techniques ; Shaw Potassium Channels/genetics
Czasopismo naukowe
Tytuł :
Involvement of small-conductance Ca oscillations in rat pinealocytes.
Autorzy :
Ando S; Department of Molecular and Cellular Pharmacology, Graduate School of Pharmaceutical Sciences, Nagoya City University, 3-1 Tanabedori Mizuhoku, Nagoya, 467-8603, Japan.
Mizutani H; Department of Molecular and Cellular Pharmacology, Graduate School of Pharmaceutical Sciences, Nagoya City University, 3-1 Tanabedori Mizuhoku, Nagoya, 467-8603, Japan.
Muramatsu M; Department of Molecular and Cellular Pharmacology, Graduate School of Pharmaceutical Sciences, Nagoya City University, 3-1 Tanabedori Mizuhoku, Nagoya, 467-8603, Japan.
Hagihara Y; Department of Molecular and Cellular Pharmacology, Graduate School of Pharmaceutical Sciences, Nagoya City University, 3-1 Tanabedori Mizuhoku, Nagoya, 467-8603, Japan.
Mishima H; Department of Molecular and Cellular Pharmacology, Graduate School of Pharmaceutical Sciences, Nagoya City University, 3-1 Tanabedori Mizuhoku, Nagoya, 467-8603, Japan.
Kondo R; Department of Molecular and Cellular Pharmacology, Graduate School of Pharmaceutical Sciences, Nagoya City University, 3-1 Tanabedori Mizuhoku, Nagoya, 467-8603, Japan.
Suzuki Y; Department of Molecular and Cellular Pharmacology, Graduate School of Pharmaceutical Sciences, Nagoya City University, 3-1 Tanabedori Mizuhoku, Nagoya, 467-8603, Japan.
Imaizumi Y; Department of Molecular and Cellular Pharmacology, Graduate School of Pharmaceutical Sciences, Nagoya City University, 3-1 Tanabedori Mizuhoku, Nagoya, 467-8603, Japan.
Yamamura H; Department of Molecular and Cellular Pharmacology, Graduate School of Pharmaceutical Sciences, Nagoya City University, 3-1 Tanabedori Mizuhoku, Nagoya, 467-8603, Japan. Electronic address: .
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Źródło :
Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2022 Jul 30; Vol. 615, pp. 157-162. Date of Electronic Publication: 2022 May 21.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Melatonin*/metabolism
Pineal Gland*/metabolism
Potassium Channels, Calcium-Activated*/metabolism
Animals ; Apamin/pharmacology ; Calcium/metabolism ; Large-Conductance Calcium-Activated Potassium Channels/metabolism ; Pyrazoles/pharmacology ; Rats ; Small-Conductance Calcium-Activated Potassium Channels/metabolism
Czasopismo naukowe
Tytuł :
Kv1.3 K Channel Physiology Assessed by Genetic and Pharmacological Modulation.
Autorzy :
Varanita T; Department of Biology, University of Padova, Padova, Italy.
Angi B; Department of Biology, University of Padova, Padova, Italy.
Scattolini V; Department of Biology, University of Padova, Padova, Italy.
Szabo I; Department of Biology, University of Padova, Padova, Italy.
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Źródło :
Physiology (Bethesda, Md.) [Physiology (Bethesda)] 2023 Jan 01; Vol. 38 (1), pp. 0. Date of Electronic Publication: 2022 Aug 23.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Potassium Channels, Voltage-Gated*
Animals ; Potassium Channels
Czasopismo naukowe
Tytuł :
Structural basis for the activity regulation of a potassium channel AKT1 from Arabidopsis.
Autorzy :
Lu Y; State Key Laboratory for Agrobiotechnology, Frontiers Science Center for Molecular Design Breeding, College of Biological Sciences, China Agricultural University, Beijing, China.
Yu M; State Key Laboratory of Plant Physiology and Biochemistry, College of Biological Sciences, China Agricultural University, Beijing, China.
Jia Y; State Key Laboratory for Agrobiotechnology, Frontiers Science Center for Molecular Design Breeding, College of Biological Sciences, China Agricultural University, Beijing, China.
Yang F; State Key Laboratory for Agrobiotechnology, Frontiers Science Center for Molecular Design Breeding, College of Biological Sciences, China Agricultural University, Beijing, China.
Zhang Y; State Key Laboratory for Agrobiotechnology, Frontiers Science Center for Molecular Design Breeding, College of Biological Sciences, China Agricultural University, Beijing, China.
Xu X; State Key Laboratory for Agrobiotechnology, Frontiers Science Center for Molecular Design Breeding, College of Biological Sciences, China Agricultural University, Beijing, China.
Li X; Technology Center for Protein Sciences, Ministry of Education Key Laboratory of Protein Sciences, School of Life Sciences, Tsinghua University, Beijing, China.
Yang F; Technology Center for Protein Sciences, Ministry of Education Key Laboratory of Protein Sciences, School of Life Sciences, Tsinghua University, Beijing, China.
Lei J; Technology Center for Protein Sciences, Ministry of Education Key Laboratory of Protein Sciences, School of Life Sciences, Tsinghua University, Beijing, China.
Wang Y; State Key Laboratory of Plant Physiology and Biochemistry, College of Biological Sciences, China Agricultural University, Beijing, China. .
Yang G; State Key Laboratory for Agrobiotechnology, Frontiers Science Center for Molecular Design Breeding, College of Biological Sciences, China Agricultural University, Beijing, China. .
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Źródło :
Nature communications [Nat Commun] 2022 Sep 27; Vol. 13 (1), pp. 5682. Date of Electronic Publication: 2022 Sep 27.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Arabidopsis*/metabolism
Arabidopsis Proteins*/metabolism
Potassium Channels, Voltage-Gated*/chemistry
Potassium/metabolism ; Potassium Channels/chemistry
Czasopismo naukowe
Tytuł :
A novel loss-of-function mutation of the voltage-gated potassium channel Kv10.2 involved in epilepsy and autism.
Autorzy :
Galán-Vidal J; Cell Cycle, Stem Cell Fate and Cancer Laboratory, Institute for Research Marqués de Valdecilla (IDIVAL), 39011, Santander, Spain.
Socuéllamos PG; Instituto de Investigaciones Biomédicas Alberto Sols, IIBM, CSIC-UAM, Madrid, Spain.; Spanish Network for Biomedical Research in Cardiovascular Research (CIBERCV), Instituto de Salud Carlos III, Madrid, Spain.
Baena-Nuevo M; Instituto de Investigaciones Biomédicas Alberto Sols, IIBM, CSIC-UAM, Madrid, Spain.; Spanish Network for Biomedical Research in Cardiovascular Research (CIBERCV), Instituto de Salud Carlos III, Madrid, Spain.
Contreras L; Cell Cycle, Stem Cell Fate and Cancer Laboratory, Institute for Research Marqués de Valdecilla (IDIVAL), 39011, Santander, Spain.
González T; Instituto de Investigaciones Biomédicas Alberto Sols, IIBM, CSIC-UAM, Madrid, Spain.; Spanish Network for Biomedical Research in Cardiovascular Research (CIBERCV), Instituto de Salud Carlos III, Madrid, Spain.
Pérez-Poyato MS; Neuropediatric, University Hospital Marqués de Valdecilla, 39008, Santander, Spain.
Valenzuela C; Instituto de Investigaciones Biomédicas Alberto Sols, IIBM, CSIC-UAM, Madrid, Spain. .; Spanish Network for Biomedical Research in Cardiovascular Research (CIBERCV), Instituto de Salud Carlos III, Madrid, Spain. .
González-Lamuño D; Cell Cycle, Stem Cell Fate and Cancer Laboratory, Institute for Research Marqués de Valdecilla (IDIVAL), 39011, Santander, Spain. .; Paediatric Department, University of Cantabria University, Marqués de Valdecilla Hospital, 39008, Santander, Spain. .
Gandarillas A; Cell Cycle, Stem Cell Fate and Cancer Laboratory, Institute for Research Marqués de Valdecilla (IDIVAL), 39011, Santander, Spain. .; INSERM, Occitanie Méditerranée, 34394, Montpellier, France. .
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Źródło :
Orphanet journal of rare diseases [Orphanet J Rare Dis] 2022 Sep 06; Vol. 17 (1), pp. 345. Date of Electronic Publication: 2022 Sep 06.
Typ publikacji :
Journal Article
MeSH Terms :
Autistic Disorder*
Epilepsy*/drug therapy
Epilepsy*/genetics
Epilepsy*/metabolism
Potassium Channels, Voltage-Gated*/genetics
Acetazolamide ; Humans ; Mutation/genetics ; Potassium Channels/genetics
Czasopismo naukowe
Tytuł :
Kv Channel Ancillary Subunits: Where Do We Go from Here?
Autorzy :
Abbott GW; Bioelectricity Laboratory, Department of Physiology and Biophysics, School of Medicine, University of California, Irvine, California.
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Źródło :
Physiology (Bethesda, Md.) [Physiology (Bethesda)] 2022 Sep 01; Vol. 37 (5), pp. 0.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Potassium Channels, Voltage-Gated*/metabolism
Humans ; Potassium/metabolism ; Potassium Channels/physiology ; Protein Subunits/metabolism
Czasopismo naukowe
Tytuł :
Induction of potassium channel regulator KCNE4 in a submandibular lymph node metastasis model.
Autorzy :
Mano R; Department of Oral and Maxillofacial Surgery, Faculty of Medicine, Fukuoka University, Fukuoka, Japan.; Department of Regenerative Medicine and Transplantation, Faculty of Medicine, Fukuoka University, Nanakuma 7-45-1, Jonan-ku, Fukuoka, Japan.
Tanaka T; Department of Regenerative Medicine and Transplantation, Faculty of Medicine, Fukuoka University, Nanakuma 7-45-1, Jonan-ku, Fukuoka, Japan.
Hashiguchi S; Department of Oral and Maxillofacial Surgery, Faculty of Medicine, Fukuoka University, Fukuoka, Japan.; Department of Regenerative Medicine and Transplantation, Faculty of Medicine, Fukuoka University, Nanakuma 7-45-1, Jonan-ku, Fukuoka, Japan.
Takahashi H; Department of Gastroenterological Surgery, Faculty of Medicine, Fukuoka University, Fukuoka, Japan.
Sakata N; Department of Regenerative Medicine and Transplantation, Faculty of Medicine, Fukuoka University, Nanakuma 7-45-1, Jonan-ku, Fukuoka, Japan. .
Kondo S; Department of Oral and Maxillofacial Surgery, Faculty of Medicine, Fukuoka University, Fukuoka, Japan.
Kodama S; Department of Regenerative Medicine and Transplantation, Faculty of Medicine, Fukuoka University, Nanakuma 7-45-1, Jonan-ku, Fukuoka, Japan. .
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Źródło :
Scientific reports [Sci Rep] 2022 Aug 01; Vol. 12 (1), pp. 13208. Date of Electronic Publication: 2022 Aug 01.
Typ publikacji :
Journal Article
MeSH Terms :
Melanoma, Experimental*/pathology
Potassium Channels, Voltage-Gated*/metabolism
Animals ; Antigens, Differentiation/metabolism ; Carrier Proteins/metabolism ; Endothelial Cells/metabolism ; Humans ; Lymph Nodes/pathology ; Lymphatic Metastasis/pathology ; Mice ; Microfilament Proteins/metabolism ; Potassium Channels/metabolism ; Sentinel Lymph Node Biopsy
Czasopismo naukowe
Tytuł :
Diversification of Potassium Currents in Excitable Cells via Kvβ Proteins.
Autorzy :
Dwenger MM; Department of Medicine, University of Louisville, Louisville, KY 40202, USA.
Raph SM; Department of Pharmacology & Toxicology, University of Louisville, Louisville, KY 40202, USA.
Baba SP; Department of Medicine, University of Louisville, Louisville, KY 40202, USA.
Moore JB 4th; Department of Medicine, University of Louisville, Louisville, KY 40202, USA.
Nystoriak MA; Department of Medicine, University of Louisville, Louisville, KY 40202, USA.; Department of Pharmacology & Toxicology, University of Louisville, Louisville, KY 40202, USA.
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Źródło :
Cells [Cells] 2022 Jul 18; Vol. 11 (14). Date of Electronic Publication: 2022 Jul 18.
Typ publikacji :
Journal Article; Review; Research Support, N.I.H., Extramural
MeSH Terms :
Potassium*/metabolism
Potassium Channels, Voltage-Gated*/metabolism
Cell Membrane/metabolism ; Membrane Potentials/physiology ; Potassium Channels/metabolism
Czasopismo naukowe
Tytuł :
Discovery of Novel Activators of Large-Conductance Calcium-Activated Potassium Channels for the Treatment of Cerebellar Ataxia.
Autorzy :
Srinivasan SR; Brigham and Women's Hospital, Department of Neurology, Boston, Massachusetts (S.R.S.); University of Texas Southwestern Medical Center, Department of Neurology, Dallas, Texas (H.H., V.G.S.); University of Michigan, Department of Neurology, Ann Arbor, Michigan (S.R.S., W.-C.C.); University of California, Davis, Department of Pharmacology, Davis, California (J.A.N., H.M.N., H.W.); and Nanion Technologies, Munich, Germany (T.S.).
Huang H; Brigham and Women's Hospital, Department of Neurology, Boston, Massachusetts (S.R.S.); University of Texas Southwestern Medical Center, Department of Neurology, Dallas, Texas (H.H., V.G.S.); University of Michigan, Department of Neurology, Ann Arbor, Michigan (S.R.S., W.-C.C.); University of California, Davis, Department of Pharmacology, Davis, California (J.A.N., H.M.N., H.W.); and Nanion Technologies, Munich, Germany (T.S.).
Chang WC; Brigham and Women's Hospital, Department of Neurology, Boston, Massachusetts (S.R.S.); University of Texas Southwestern Medical Center, Department of Neurology, Dallas, Texas (H.H., V.G.S.); University of Michigan, Department of Neurology, Ann Arbor, Michigan (S.R.S., W.-C.C.); University of California, Davis, Department of Pharmacology, Davis, California (J.A.N., H.M.N., H.W.); and Nanion Technologies, Munich, Germany (T.S.).
Nasburg JA; Brigham and Women's Hospital, Department of Neurology, Boston, Massachusetts (S.R.S.); University of Texas Southwestern Medical Center, Department of Neurology, Dallas, Texas (H.H., V.G.S.); University of Michigan, Department of Neurology, Ann Arbor, Michigan (S.R.S., W.-C.C.); University of California, Davis, Department of Pharmacology, Davis, California (J.A.N., H.M.N., H.W.); and Nanion Technologies, Munich, Germany (T.S.).
Nguyen HM; Brigham and Women's Hospital, Department of Neurology, Boston, Massachusetts (S.R.S.); University of Texas Southwestern Medical Center, Department of Neurology, Dallas, Texas (H.H., V.G.S.); University of Michigan, Department of Neurology, Ann Arbor, Michigan (S.R.S., W.-C.C.); University of California, Davis, Department of Pharmacology, Davis, California (J.A.N., H.M.N., H.W.); and Nanion Technologies, Munich, Germany (T.S.).
Strassmaier T; Brigham and Women's Hospital, Department of Neurology, Boston, Massachusetts (S.R.S.); University of Texas Southwestern Medical Center, Department of Neurology, Dallas, Texas (H.H., V.G.S.); University of Michigan, Department of Neurology, Ann Arbor, Michigan (S.R.S., W.-C.C.); University of California, Davis, Department of Pharmacology, Davis, California (J.A.N., H.M.N., H.W.); and Nanion Technologies, Munich, Germany (T.S.).
Wulff H; Brigham and Women's Hospital, Department of Neurology, Boston, Massachusetts (S.R.S.); University of Texas Southwestern Medical Center, Department of Neurology, Dallas, Texas (H.H., V.G.S.); University of Michigan, Department of Neurology, Ann Arbor, Michigan (S.R.S., W.-C.C.); University of California, Davis, Department of Pharmacology, Davis, California (J.A.N., H.M.N., H.W.); and Nanion Technologies, Munich, Germany (T.S.).
Shakkottai VG; Brigham and Women's Hospital, Department of Neurology, Boston, Massachusetts (S.R.S.); University of Texas Southwestern Medical Center, Department of Neurology, Dallas, Texas (H.H., V.G.S.); University of Michigan, Department of Neurology, Ann Arbor, Michigan (S.R.S., W.-C.C.); University of California, Davis, Department of Pharmacology, Davis, California (J.A.N., H.M.N., H.W.); and Nanion Technologies, Munich, Germany (T.S.) .
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Źródło :
Molecular pharmacology [Mol Pharmacol] 2022 Jul; Vol. 102 (1), pp. 438-449. Date of Electronic Publication: 2022 Apr 30.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
MeSH Terms :
Cerebellar Ataxia*/drug therapy
Potassium Channels, Calcium-Activated*
Spinocerebellar Ataxias*/metabolism
Animals ; Ataxia ; Calcium/metabolism ; Large-Conductance Calcium-Activated Potassium Channels ; Mice ; Potassium/metabolism
Czasopismo naukowe
Tytuł :
The potassium channel auxiliary subunit Kvβ2 ( Kcnab2 ) regulates Kv1 channels and dopamine neuron firing.
Autorzy :
Yee JX; Department of Pharmacology, University of Washington, Seattle, Washington.
Rastani A; Department of Pharmacology, University of Washington, Seattle, Washington.
Soden ME; Department of Pharmacology, University of Washington, Seattle, Washington.
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Źródło :
Journal of neurophysiology [J Neurophysiol] 2022 Jul 01; Vol. 128 (1), pp. 62-72. Date of Electronic Publication: 2022 Jun 15.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Dopaminergic Neurons*/metabolism
Potassium Channels*/metabolism
Animals ; Mice ; Shaker Superfamily of Potassium Channels/genetics
Czasopismo naukowe

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