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Wyszukujesz frazę ""Protein Binding drug effects"" wg kryterium: Temat


Tytuł :
Phosphatidylinositol-4,5-bisphosphate is required for KCNQ1/KCNE1 channel function but not anterograde trafficking
Autorzy :
Andrew Tinker
Stephen C. Harmer
Alice A. Royal
Pokaż więcej
Temat :
Animals
CHO Cells
Cell Membrane/drug effects
Cricetinae
Cricetulus
Endoplasmic Reticulum/drug effects
Genes, Reporter
Golgi Apparatus/drug effects
HEK293 Cells
Humans
Ion Channel Gating/drug effects
KCNQ1 Potassium Channel/metabolism
Mutation/genetics
Phosphatidylinositol 4,5-Diphosphate/metabolism
Potassium Channels, Voltage-Gated/metabolism
Protein Binding/drug effects
Protein Multimerization/drug effects
Protein Transport/drug effects
Sirolimus/pharmacology
Research Article
Research and Analysis Methods
Biological Cultures
Cell Cultures
Biology and Life Sciences
Biochemistry
Lipids
Enzymology
Enzymes
Phosphatases
Proteins
Biophysics
Ion Channels
Potassium Channels
Physical Sciences
Physics
Physiology
Electrophysiology
Medicine and Health Sciences
Neurophysiology
Neuroscience
Cell Biology
Cell Physiology
Membrane Trafficking
Chemistry
Chemical Properties
Dimerization
Physical Chemistry
Cellular Structures and Organelles
Cell Membranes
Multidisciplinary
Phosphatidylinositol 4,5-bisphosphate
chemistry.chemical_compound
chemistry
Golgi apparatus
symbols.namesake
symbols
Potassium channel
Chemically induced dimerization
Cardiac action potential
Cell biology
Endoplasmic reticulum
Plasma protein binding
Ion channel
Medicine
Science
lipids (amino acids, peptides, and proteins)
Źródło :
Royal, A A, Tinker, A & Harmer, S C 2017, ' Phosphatidylinositol-4,5-bisphosphate is required for KCNQ1/KCNE1 channel function but not anterograde trafficking ', PLoS ONE, vol. 12, no. 10, e0186293 . https://doi.org/10.1371/journal.pone.0186293
PLoS ONE
Crossref
PLoS ONE, Vol 12, Iss 10, p e0186293 (2017)
Opis pliku :
application/pdf
Dostępność :
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc2361b69062046cf19d869f672b41c0
https://research-information.bris.ac.uk/en/publications/e514aac4-3f9f-4fe8-bf0c-8fe083982c1b
Tytuł :
Enhancer-Mediated Oncogenic Function of the Menin Tumor Suppressor in Breast Cancer
Autorzy :
Charles P. Lin
Elgene Lim
David Chi
Henry W. Long
E.S. Vos
Alba Font-Tello
Wouter de Laat
Myles Brown
K. M. A. Dreijerink
Jennifer Cook
Anna C. Groner
Lei Gu
Jaime M. Reyes
Prakash Rao
Pokaż więcej
Temat :
Breast Neoplasms
Cell Line, Tumor
Cell Proliferation
Enhancer Elements, Genetic
Estradiol
Estrogen Receptor alpha
Female
GATA3 Transcription Factor
Gene Expression Regulation, Neoplastic
Genomics
Hepatocyte Nuclear Factor 3-alpha
Histones
Humans
Lysine
Methylation
Oncogenes
Promoter Regions, Genetic
Protein Binding
Proto-Oncogene Proteins
Transcription, Genetic
Journal Article
breast cancer
MEN1
Tumor Suppressor
oncogene
transcription
epigenetics
menin
histone H3K4 trimethylation
enhancer
tumor suppressor
Biochemistry, Genetics and Molecular Biology(all)
Article
lcsh:Biology (General)
lcsh:QH301-705.5
Cell Line
Tumor
Enhancer Elements
Genetic
Gene Expression Regulation
Neoplastic
Promoter Regions
Biochemistry
Genetics and Molecular Biology(all)
Breast Neoplasms/genetics
Genetic/genetics
Estradiol/pharmacology
Estrogen Receptor alpha/metabolism
GATA3 Transcription Factor/metabolism
Hepatocyte Nuclear Factor 3-alpha/metabolism
Histones/metabolism
Lysine/metabolism
Protein Binding/drug effects
Proto-Oncogene Proteins/genetics
Enhancer Elements, Genetic/genetics
General Biochemistry, Genetics and Molecular Biology
Cancer research
Oncogene
Carcinogenesis
medicine.disease_cause
medicine
GATA3
Enhancer
FOXA1
Breast cancer
medicine.disease
Biology
Gene product
endocrine system diseases
endocrine system
congenital, hereditary, and neonatal diseases and abnormalities
Źródło :
Cell Reports, 18(10), 2359-2372. Cell Press
Cell Reports, 18 (10)
Cell Reports [E], 18(10), 2359. Cell Press
Cell Reports, Vol 18, Iss 10, Pp 2359-2372 (2017)
Crossref
Opis pliku :
application/application/pdf; image/pdf
Dostępność :
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a9ee6b521b76dfb9315f27ecf511759
https://pure.knaw.nl/portal/en/publications/1a0ebc28-ca10-4dd8-9da9-8c0649a60248
Tytuł :
Inhibiting fungal multidrug resistance by disrupting an activator–Mediator interaction
Autorzy :
Jl, Nishikawa
Boeszoermenyi A
La, Vale-Silva
Torelli R
Posteraro B
Yj, Sohn
Ji F
Gelev V
Sanglard D
Sanguinetti M
Ri, Sadreyev
Mukherjee G
Bhyravabhotla J
Sj, Buhrlage
Ns, Gray
Wagner G
Am, Näär
Haribabu Arthanari
Pokaż więcej
Temat :
Multidisciplinary
Activator (genetics)
Microbiology
Transcription factor
Eukaryotic transcription
Fungal protein
Transcription (biology)
Mediator
Regulation of gene expression
Biology
Candida glabrata
biology.organism_classification
Article
Animals
Antifungal Agents/pharmacology
Binding Sites/drug effects
Candida glabrata/drug effects
Candida glabrata/genetics
Candidiasis/drug therapy
Candidiasis/microbiology
DNA-Binding Proteins/genetics
DNA-Binding Proteins/metabolism
Drug Resistance, Fungal/drug effects
Drug Resistance, Multiple, Fungal/drug effects
Fluconazole/pharmacology
Fungal Proteins/metabolism
Gene Expression Regulation, Fungal/drug effects
Hydrazines/pharmacokinetics
Hydrazines/pharmacology
Ketoconazole/pharmacology
Mediator Complex/chemistry
Mediator Complex/metabolism
Mice
Models, Molecular
Nuclear Magnetic Resonance, Biomolecular
Protein Binding/drug effects
Protein Structure, Tertiary
Saccharomyces cerevisiae Proteins/chemistry
Saccharomyces cerevisiae Proteins/genetics
Thiourea/analogs & derivatives
Thiourea/pharmacokinetics
Trans-Activators/chemistry
Trans-Activators/metabolism
Transcription Factors/genetics
Transcription Factors/metabolism
Transcriptional Activation/drug effects
Up-Regulation/drug effects
Źródło :
Crossref
Nature
Europe PubMed Central
Nature, vol. 530, no. 7591, pp. 485-489
Opis pliku :
application/pdf
Dostępność :
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::387b05bb85fa8b6fb9b167c377f136ee
Tytuł :
Chronic Δ9-Tetrahydrocannabinol Exposure Induces a Sensitization of Dopamine D2/3 Receptors in the Mesoaccumbens and Nigrostriatal Systems
Autorzy :
Vicente Ibáñez
Thierry Steimer
Benjamin B. Tournier
Nathalie Ginovart
Philippe Millet
Marcelle Moulin-Sallanon
Pokaż więcej
Temat :
Psychiatry and Mental health
Pharmacology
Amphetamine
medicine.drug
medicine
Tetrahydrocannabinol
Cannabinoid
medicine.medical_treatment
Neurotransmission
Quinpirole
Dopamine
Postsynaptic potential
Chemistry
Dopamine receptor D2
Original Article
ddc:616.89
Amphetamine/pharmacology
Analysis of Variance
Animals
Basal Ganglia/diagnostic imaging/drug effects/metabolism
Benzamides/pharmacokinetics
Dopamine Agonists/pharmacology
Dopamine Antagonists/pharmacokinetics
Dopamine Uptake Inhibitors/pharmacology
Dose-Response Relationship, Drug
Dronabinol/pharmacology
Drug Interactions
Fluorodeoxyglucose F18/pharmacokinetics
Gene Expression Regulation/drug effects
Locomotion/drug effects
Male
Nucleus Accumbens/diagnostic imaging/drug effects/metabolism
Positron-Emission Tomography
Protein Binding/drug effects
Psychotropic Drugs/pharmacology
Quinpirole/pharmacology
RNA, Messenger/metabolism
Rats
Rats, Sprague-Dawley
Receptors, Dopamine D2/genetics/metabolism
Tritium/pharmacokinetics
Vitamin K 1/analogs & derivatives/pharmacokinetics
mental disorders
organic chemicals
Źródło :
Crossref
Neuropsychopharmacology, Vol. 37, No 11 (2012) pp. 2355-2367
Dostępność :
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eeeaa2da2394003f0083accf7babfb12
http://www.nature.com/articles/npp201291.pdf
Tytuł :
The AP-1 binding sites located in the pol gene intragenic regulatory region of HIV-1 are important for viral replication
Autorzy :
Olivier Rohr
Valérie Martinelli
Gianfranco Pancino
Caroline Vanhulle
Arsène Burny
Benoît Van Driessche
Georges Herbein
Laurence Colin
Annie David
Stéphane de Walque
Carine Van Lint
Allan Guiguen
Anna Bergamaschi
Thomas Cherrier
Nathalie Vandenhoudt
Pokaż więcej
Temat :
[SDV.BC]Life Sciences [q-bio]/Cellular Biology
Sciences bio-médicales et agricoles
Base Sequence
Binding Sites
Enhancer Elements, Genetic -- genetics
Genes, Dominant -- genetics
Genes, pol -- genetics
HIV-1 -- genetics -- physiology
Humans
Jurkat Cells
Macrophages -- drug effects -- virology
Molecular Sequence Data
Monocytes -- drug effects -- virology
Point Mutation -- genetics
Protein Binding -- drug effects
Proto-Oncogene Proteins c-fos -- metabolism
Proto-Oncogene Proteins c-jun -- metabolism
RNA Polymerase II -- metabolism
Regulatory Sequences, Nucleic Acid -- genetics
T-Lymphocytes -- drug effects -- virology
Tetradecanoylphorbol Acetate -- pharmacology
Transcription Factor AP-1 -- metabolism
Virus Replication -- genetics
tat Gene Products, Human Immunodeficiency Virus
lcsh:Medicine
lcsh:R
lcsh:Science
lcsh:Q
Multidisciplinary
RNA polymerase II
biology.protein
biology
Binding site
DNA binding site
Virology
Point mutation
Thymidine kinase
Viral replication
Transcription factor
Enhancer
Research Article
Biology
Biochemistry
Nucleic acids
DNA
DNA replication
Microbiology
Viral Replication
Viral Nucleic Acid
Viral Replication Complex
Immunodeficiency Viruses
Enhancer Elements, Genetic/genetics
Genes, Dominant/genetics
Genes, pol/genetics
HIV-1/genetics/physiology
Macrophages/drug effects/virology
Monocytes/drug effects/virology
Point Mutation/genetics
Protein Binding/drug effects
Proto-Oncogene Proteins c-fos/metabolism
Proto-Oncogene Proteins c-jun/metabolism
RNA Polymerase II/metabolism
Regulatory Sequences, Nucleic Acid/genetics
T-Lymphocytes/drug effects/virology
Tetradecanoylphorbol Acetate/pharmacology
Transcription Factor AP-1/metabolism
Virus Replication/genetics
Biochemistry, biophysics & molecular biology [Life sciences]
Biochimie, biophysique & biologie moléculaire [Sciences du vivant]
Źródło :
PLoS ONE
PLoS ONE, Public Library of Science, 2011, 6 (4), ⟨10.1371/journal.pone.0019084⟩
PloS one, 6 (4
PLoS ONE, Vol 6, Iss 4, p e19084 (2011)
Crossref
PLoS ONE, 6(4), 19084. United States (2011).
Opis pliku :
1 full-text file(s): application/pdf
Dostępność :
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::baf714814dc2c1baa5923cf645c2da8e
https://hal.archives-ouvertes.fr/hal-02270192

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