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Wyszukujesz frazę ""Protein Kinase Inhibitors chemistry"" wg kryterium: Temat


Wyświetlanie 1-6 z 6
Tytuł :
Dual action antifungal small molecule modulates multidrug efflux and TOR signaling
Autorzy :
Shekhar-Guturja, Tanvi
Gunaherath, G M Kamal B
Wijeratne, E M Kithsiri
Lambert, Jean-Philippe
Averette, Anna F
Lee, Soo Chan
Kim, Taeyup
Bahn, Yong-Sun
Tripodi, Farida
Ammar, Ron
Döhl, Katja
Niewola-Staszkowska, Karolina
Schmitt, Lutz
Loewith, Robbie J
Roth, Frederick P
Sanglard, Dominique
Andes, David
Nislow, Corey
Coccetti, Paola
Gingras, Anne-Claude
Heitman, Joseph
Gunatilaka, A A Leslie
Cowen, Leah E
Pokaż więcej
Temat :
ddc:570
ddc:590
ATP-Binding Cassette Transporters/genetics/metabolism
Antifungal Agents/chemistry/pharmacology
Depsipeptides/chemical synthesis/chemistry/pharmacology
Drug Resistance
Fungal/drug effects
Multiple/drug effects
Fungi/drug effects/metabolism
HSP90 Heat-Shock Proteins/antagonists & inhibitors/metabolism
Microbial Sensitivity Tests
Mycoses/drug therapy/microbiology
Protein Kinase Inhibitors/chemical synthesis/chemistry/pharmacology
Saccharomyces cerevisiae Proteins/genetics/metabolism
Signal Transduction/drug effects
Small Molecule Libraries/chemistry/pharmacology
TOR Serine-Threonine Kinases/antagonists & inhibitors/metabolism
Cell Biology
Molecular Biology
TOR signaling
Microbiology
Kinase
Beauvericin
chemistry.chemical_compound
chemistry
Hsp90
biology.protein
biology
Drug resistance
Mechanism of action
medicine.symptom
medicine
Biotinylation
Efflux
Article
ATP-Binding Cassette Transporters/genetics
ATP-Binding Cassette Transporters/metabolism
Antifungal Agents/chemistry
Antifungal Agents/pharmacology
Depsipeptides/chemical synthesis
Depsipeptides/chemistry
Depsipeptides/pharmacology
Drug Resistance, Fungal/drug effects
Drug Resistance, Multiple/drug effects
Fungi/drug effects
Fungi/metabolism
HSP90 Heat-Shock Proteins/antagonists & inhibitors
HSP90 Heat-Shock Proteins/metabolism
Mycoses/drug therapy
Mycoses/microbiology
Protein Kinase Inhibitors/chemical synthesis
Protein Kinase Inhibitors/chemistry
Protein Kinase Inhibitors/pharmacology
Saccharomyces cerevisiae Proteins/genetics
Saccharomyces cerevisiae Proteins/metabolism
Small Molecule Libraries/chemistry
Small Molecule Libraries/pharmacology
TOR Serine-Threonine Kinases/antagonists & inhibitors
TOR Serine-Threonine Kinases/metabolism
Źródło :
Nature chemical biology, Vol. 12, No 10 (2016) pp. 867-875
Crossref
Nature chemical biology
Nature chemical biology, vol. 12, no. 10, pp. 867-875
Opis pliku :
application/pdf
Dostępność :
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df123ffb668df12b0d34f328ccb34f16
https://archive-ouverte.unige.ch/unige:103221
Tytuł :
Stereospecific targeting of MTH1 by (S)-crizotinib as an anticancer strategy
Autorzy :
Huber, K. V.
Salah, E.
Radic, B.
Gridling, M.
Jon Elkins
Stukalov, A.
Jemth, A. S.
Göktürk, C.
Sanjiv, K.
Strömberg, K.
Pham, T.
Berglund, U. W.
Colinge, J.
Bennett, K. L.
Loizou, J. I.
Helleday, T.
Knapp, S.
Superti-Furga, G.
Pokaż więcej
Temat :
Multidisciplinary
GTPase
DNA repair
Biology
Proto-Oncogene Proteins p21(ras)
Enzyme
chemistry.chemical_classification
chemistry
Crizotinib
medicine.drug
medicine
Kinase
DNA
chemistry.chemical_compound
Biochemistry
Cancer research
KRAS
medicine.disease_cause
SCID
Nucleotides/metabolism
Humans
Female
Animals
Models
Molecular
Mice
Disease Models
Animal
DNA Repair
Xenograft Model Antitumor Assays
Proteomics
Protein Conformation
Aminoquinolines/pharmacology
Antineoplastic Agents/chemistry/*pharmacology
Colonic Neoplasms/drug therapy/genetics/pathology
Crystallization
DNA Breaks
Single-Stranded/drug effects
DNA Repair Enzymes/*antagonists & inhibitors/biosynthesis/chemistry/*metabolism
Homeostasis/drug effects
inhibitors/biosynthesis/chemistry/*metabolism
Phosphoric Monoester Hydrolases/*antagonists &
Protein Kinase Inhibitors/chemistry/*pharmacology
Proto-Oncogene Proteins/genetics
Pyrazoles/chemistry/*pharmacology
Pyridines/chemistry/*pharmacology
ras Proteins/genetics
Substrate Specificity
[SDV.CAN]Life Sciences [q-bio]/Cancer
Article
stereoselectivity
drug
MTH1
crizotinib
cancer
Źródło :
Crossref
Nature
Nature, Nature Publishing Group, 2014, 508, pp.222--7. ⟨10.1038/nature13194⟩
Scopus-Elsevier
Nature; Vol 508
Dostępność :
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cf6d6ad2f3b07657ef3e0a6f7a30e0c
http://ora.ox.ac.uk/objects/uuid:28882238-b520-469b-8eb9-adce7a4ef327
    Wyświetlanie 1-6 z 6

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