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Tytuł :
Organ manifestations of COVID-19: what have we learned so far (not only) from autopsies?
Autorzy :
Jonigk D; Institute of Pathology, Hannover Medical School, Hannover, Germany. .
Werlein C; Institute of Pathology, Hannover Medical School, Hannover, Germany.
Acker T; Institute of Neuropathology, University Hospital Giessen and Marburg, Giessen, Germany.
Aepfelbacher M; Institute of Medical Microbiology, Virology, and Hygiene, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Amann KU; Department of Nephropathology, University Hospital Erlangen-Nürnberg, Erlangen, Germany.
Baretton G; Department of Pathology, University Hospital Dresden, Dresden, Germany.
Barth P; Gerhard Domagk Institute of Pathology, University Hospital Münster, Münster, Germany.
Bohle RM; Department of Pathology, University Hospital Saarland Homburg, Homburg, Germany.
Büttner A; Institute of Forensic Medicine, University Medical Center Rostock, Rostock, Germany.
Büttner R; Department of Pathology, University Hospital Cologne, Cologne, Germany.
Dettmeyer R; Department of Legal Medicine, University Hospital Giessen and Marburg, Giessen, Germany.
Eichhorn P; Department of Pathology, University Hospital Erlangen-Nürnberg, Erlangen, Germany.
Elezkurtaj S; Department of Pathology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.
Esposito I; Department of Pathology, University Hospital Düsseldorf, Düsseldorf, Germany.
Evert K; Department of Pathology, University Hospital Regensburg, Regensburg, Germany.
Evert M; Department of Pathology, University Hospital Regensburg, Regensburg, Germany.
Fend F; Department of Pathology, University Hospital Tübingen, Tübingen, Germany.
Gaßler N; Department of Pathology, University Hospital Jena, Jena, Germany.
Gattenlöhner S; Department of Pathology, University Hospital Giessen and Marburg, Giessen, Germany.
Glatzel M; Institute of Neuropathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Göbel H; Department of Pathology, University Hospital Cologne, Cologne, Germany.
Gradhand E; Senckenberg Institute of Pathology, University Hospital Frankfurt, Frankfurt, Germany.
Hansen T; Department of Pathology, University Hospital OWL of the Bielefeld University, Campus Lippe, Detmold, Germany.
Hartmann A; Department of Pathology, University Hospital Erlangen-Nürnberg, Erlangen, Germany.
Heinemann A; Department of Legal Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Heppner FL; Department of Neuropathology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.; German Center for Neurodegenerative Diseases (DZNE) Berlin, Berlin, Germany.; Cluster of Excellence, NeuroCure, Berlin, Germany.
Hilsenbeck J; Department of Pathology, University Hospital Dresden, Dresden, Germany.
Horst D; Department of Pathology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.
Kamp JC; Department of Respiratory Medicine, Hannover Medical School, Hannover, Germany.
Mall G; Department of Legal Medicine, University Hospital Jena, Jena, Germany.
Märkl B; General Pathology and Molecular Diagnostics, University Hospital Augsburg, Augsburg, Germany.
Ondruschka B; Institute of Legal Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Pablik J; Department of Pathology, University Hospital Dresden, Dresden, Germany.
Pfefferle S; Institute of Medical Microbiology, Virology, and Hygiene, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Quaas A; Department of Pathology, University Hospital Cologne, Cologne, Germany.
Radbruch H; Department of Neuropathology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.
Röcken C; Department of Pathology, University Hospital Schleswig-Holstein, Kiel, Germany.
Rosenwald A; Institute of Pathology, University of Würzburg, Würzburg, Germany.
Roth W; Department of Pathology, University Medical Center Mainz, Mainz, Germany.
Rudelius M; Institute of Pathology, Ludwig-Maximilians-Universität Munich, Munich, Germany.
Schirmacher P; Department of Pathology, Heidelberg University Hospital, Heidelberg, Germany.
Slotta-Huspenina J; Department of Pathology, TUM School of Medicine of Technical University of Munich, Munich, Germany.
Smith K; Senckenberg Institute of Pathology, University Hospital Frankfurt, Frankfurt, Germany.
Sommer L; Department of Pathology, University Hospital Dresden, Dresden, Germany.
Stock K; Department of Nephrology, TUM School of Medicine of Technical University of Munich, Munich, Germany.
Ströbel P; Department of Pathology, University Medical Center Göttingen, Göttingen, Germany.
Strobl S; Department of Pathology, University Medical Center Mainz, Mainz, Germany.
Titze U; Department of Pathology, University Hospital OWL of the Bielefeld University, Campus Lippe, Detmold, Germany.
Weirich G; Department of Pathology, TUM School of Medicine of Technical University of Munich, Munich, Germany.
Weis J; Department of Neuropathology, University Hospital RWTH Aachen, Aachen, Germany.
Werner M; Institute for Surgical Pathology, Medical Center, University of Freiburg, Freiburg, Germany.
Wickenhauser C; Department of Pathology, University Hospital Halle (Saale), Halle (Saale), Germany.
Wiech T; Department of Pathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Wild P; Senckenberg Institute of Pathology, University Hospital Frankfurt, Frankfurt, Germany.
Welte T; Department of Respiratory Medicine, Hannover Medical School, Hannover, Germany.
von Stillfried S; Institute of Pathology, University Hospital RWTH Aachen, Aachen, Germany.
Boor P; Institute of Pathology, University Hospital RWTH Aachen, Aachen, Germany. .; Department of Nephrology and Immunology, University Hospital RWTH Aachen, Aachen, Germany. .
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Źródło :
Virchows Archiv : an international journal of pathology [Virchows Arch] 2022 Aug; Vol. 481 (2), pp. 139-159. Date of Electronic Publication: 2022 Apr 01.
Typ publikacji :
Journal Article; Review
MeSH Terms :
COVID-19*
Autopsy ; Humans ; Lung/pathology ; Pandemics ; SARS-CoV-2
Czasopismo naukowe
Tytuł :
pT3 colorectal cancer revisited: a multicentric study on the histological depth of invasion in more than 1000 pT3 carcinomas-proposal for a new pT3a/pT3b subclassification.
Autorzy :
Foersch S; Institute of Pathology, University Medical Center, Mainz, Germany.
Lang-Schwarz C; Institute of Pathology, Friedrich-Alexander-University Erlangen-Nuremberg, Klinikum Bayreuth, Bayreuth, Germany.
Eckstein M; Institute of Pathology, University Hospital Erlangen, Erlangen, Germany.
Geppert C; Institute of Pathology, University Hospital Erlangen, Erlangen, Germany.
Schmitt M; Institute of Pathology, Technical University of Munich, Munich, Germany.; Institute of Pathology, Philipps University Marburg and University Hospital Marburg (UKGM), Marburg, Germany.
Konukiewitz B; Institute of Pathology, Christian-Albrechts University, Kiel, Germany.
Groll T; Institute of Pathology, Technical University of Munich, Munich, Germany.
Schicktanz F; Institute of Pathology, Technical University of Munich, Munich, Germany.
Engel J; Munich Cancer Registry (MCR), Institute for Medical Information Processing, Biometry, and Epidemiology (IBE), Ludwig-Maximilian-University (LMU), Munich, Germany.
Gleitsmann M; Institute of Pathology, Philipps University Marburg and University Hospital Marburg (UKGM), Marburg, Germany.
Westhoff CC; Institute of Pathology, Philipps University Marburg and University Hospital Marburg (UKGM), Marburg, Germany.
Frickel N; Institute of Pathology, Philipps University Marburg and University Hospital Marburg (UKGM), Marburg, Germany.
Litmeyer AS; Institute of Pathology, Philipps University Marburg and University Hospital Marburg (UKGM), Marburg, Germany.
Grass A; Institute of Pathology, Philipps University Marburg and University Hospital Marburg (UKGM), Marburg, Germany.
Jank P; Institute of Pathology, Philipps University Marburg and University Hospital Marburg (UKGM), Marburg, Germany.
Lange S; II Medizinische Klinik, Klinikum rechts der Isar, Technical University Munich, Munich, Germany.
Tschurtschenthaler M; II Medizinische Klinik, Klinikum rechts der Isar, Technical University Munich, Munich, Germany.; Institute for Translational Cancer Research, German Cancer Consortium (DKTK), Partner Site Munich, Munich, Germany.
Wilhelm D; Department of Surgery, Klinikum rechts der Isar, Technical University Munich, Munich, Germany.
Roth W; Institute of Pathology, University Medical Center, Mainz, Germany.
Vieth M; Institute of Pathology, Friedrich-Alexander-University Erlangen-Nuremberg, Klinikum Bayreuth, Bayreuth, Germany.
Denkert C; Institute of Pathology, Philipps University Marburg and University Hospital Marburg (UKGM), Marburg, Germany.
Nagtegaal I; Department of Pathology, Radboudumc, Nijmegen, The Netherlands.
Weichert W; Institute of Pathology, Technical University of Munich, Munich, Germany.; German Cancer Consortium (DKTK), Partner Site Munich, Munich, Germany.; Bavarian Cancer Center (BZKF), Munich, Germany.; Comprehensive Cancer Center Munich (CCCM), Munich, Germany.
Jesinghaus M; Institute of Pathology, Technical University of Munich, Munich, Germany. .; Institute of Pathology, Philipps University Marburg and University Hospital Marburg (UKGM), Marburg, Germany. .
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Źródło :
British journal of cancer [Br J Cancer] 2022 Jul 21. Date of Electronic Publication: 2022 Jul 21.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Expression of the Stem Cell Marker ABCB5 in Normal and Tumor Tissues.
Autorzy :
Saeed MEM; Department of Pharmaceutical Biology, Institute of Pharmaceutical and Biomedical Sciences, Johannes Gutenberg University, Mainz, Germany.
Boulos JC; Department of Pharmaceutical Biology, Institute of Pharmaceutical and Biomedical Sciences, Johannes Gutenberg University, Mainz, Germany.
Machel K; Department of Pharmaceutical Biology, Institute of Pharmaceutical and Biomedical Sciences, Johannes Gutenberg University, Mainz, Germany.
Andabili N; Department of Pharmaceutical Biology, Institute of Pharmaceutical and Biomedical Sciences, Johannes Gutenberg University, Mainz, Germany.
Marouni T; Department of Pharmaceutical Biology, Institute of Pharmaceutical and Biomedical Sciences, Johannes Gutenberg University, Mainz, Germany.
Roth W; Institute of Pathology, University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany.
Efferth T; Department of Pharmaceutical Biology, Institute of Pharmaceutical and Biomedical Sciences, Johannes Gutenberg University, Mainz, Germany; .
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Źródło :
In vivo (Athens, Greece) [In Vivo] 2022 Jul-Aug; Vol. 36 (4), pp. 1651-1666.
Typ publikacji :
Journal Article
MeSH Terms :
ATP Binding Cassette Transporter, Subfamily B, Member 1*/metabolism
Neoplastic Stem Cells*/metabolism
ATP Binding Cassette Transporter, Subfamily B/genetics ; Animals ; Biomarkers/metabolism ; Chickens ; Female ; Geese ; Humans ; Male ; Mice ; Oligochaeta ; Pregnancy ; Rats ; Skin/metabolism ; Swine
Czasopismo naukowe
Tytuł :
Integrative Analysis of Intrahepatic Cholangiocarcinoma Subtypes for Improved Patient Stratification: Clinical, Pathological, and Radiological Considerations.
Autorzy :
Gerber TS; Institute of Pathology, University Medical Center of the Johannes Gutenberg-University Mainz, 55131 Mainz, Germany.
Müller L; Department of Diagnostic and Interventional Radiology, University Medical Center of the Johannes Gutenberg-University Mainz, Langenbeckst. 1, 55131 Mainz, Germany.
Bartsch F; Department of General, Visceral and Transplant Surgery, University Medical Center of the Johannes Gutenberg-University Mainz, 55131 Mainz, Germany.
Gröger LK; Department of General, Visceral and Transplant Surgery, University Medical Center of the Johannes Gutenberg-University Mainz, 55131 Mainz, Germany.
Schindeldecker M; Institute of Pathology, University Medical Center of the Johannes Gutenberg-University Mainz, 55131 Mainz, Germany.; Tissue Biobank, University Medical Center of the Johannes Gutenberg-University Mainz, 55131 Mainz, Germany.
Ridder DA; Institute of Pathology, University Medical Center of the Johannes Gutenberg-University Mainz, 55131 Mainz, Germany.
Goeppert B; Institute of Pathology and Neuropathology, Hospital Ludwigsburg, 71640 Ludwigsburg, Germany.
Möhler M; 1st Clinic and Polyclinic of Internal Medicine, University Medical Center of the Johannes Gutenberg-University Mainz, Langenbeckst. 1, 55131 Mainz, Germany.
Dueber C; Department of Diagnostic and Interventional Radiology, University Medical Center of the Johannes Gutenberg-University Mainz, Langenbeckst. 1, 55131 Mainz, Germany.
Lang H; Department of General, Visceral and Transplant Surgery, University Medical Center of the Johannes Gutenberg-University Mainz, 55131 Mainz, Germany.
Roth W; Institute of Pathology, University Medical Center of the Johannes Gutenberg-University Mainz, 55131 Mainz, Germany.
Kloeckner R; Department of Diagnostic and Interventional Radiology, University Medical Center of the Johannes Gutenberg-University Mainz, Langenbeckst. 1, 55131 Mainz, Germany.
Straub BK; Institute of Pathology, University Medical Center of the Johannes Gutenberg-University Mainz, 55131 Mainz, Germany.
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Źródło :
Cancers [Cancers (Basel)] 2022 Jun 28; Vol. 14 (13). Date of Electronic Publication: 2022 Jun 28.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
N-Cadherin Distinguishes Intrahepatic Cholangiocarcinoma from Liver Metastases of Ductal Adenocarcinoma of the Pancreas.
Autorzy :
Gerber TS; Institute of Pathology, University Medical Center of the Johannes Gutenberg-University Mainz, 55131 Mainz, Germany.
Goeppert B; Institute of Pathology and Neuropathology, RKH Klinikum Ludwigsburg, 71640 Ludwigsburg, Germany.
Hausen A; Institute of Pathology, University Medical Center of the Johannes Gutenberg-University Mainz, 55131 Mainz, Germany.
Witzel HR; Institute of Pathology, University Medical Center of the Johannes Gutenberg-University Mainz, 55131 Mainz, Germany.
Bartsch F; Department of General, Visceral and Transplant Surgery, University Medical Center of the Johannes Gutenberg-University Mainz, 55131 Mainz, Germany.
Schindeldecker M; Institute of Pathology, University Medical Center of the Johannes Gutenberg-University Mainz, 55131 Mainz, Germany.; Tissue Biobank, University Medical Center of the Johannes Gutenberg-University Mainz, 55131 Mainz, Germany.
Gröger LK; Department of General, Visceral and Transplant Surgery, University Medical Center of the Johannes Gutenberg-University Mainz, 55131 Mainz, Germany.
Ridder DA; Institute of Pathology, University Medical Center of the Johannes Gutenberg-University Mainz, 55131 Mainz, Germany.
Cahyadi O; Institute of Pathology, University of Heidelberg, 69120 Heidelberg, Germany.
Esposito I; Institute of Pathology, University Clinic Düsseldorf, 40225 Düsseldorf, Germany.
Gaida MM; Institute of Pathology, University Medical Center of the Johannes Gutenberg-University Mainz, 55131 Mainz, Germany.
Schirmacher P; Institute of Pathology and Neuropathology, RKH Klinikum Ludwigsburg, 71640 Ludwigsburg, Germany.
Galle PR; Department of Medicine I, University Medical Center of the Johannes Gutenberg-University Mainz, 55131 Mainz, Germany.
Lang H; Department of General, Visceral and Transplant Surgery, University Medical Center of the Johannes Gutenberg-University Mainz, 55131 Mainz, Germany.
Roth W; Institute of Pathology, University Medical Center of the Johannes Gutenberg-University Mainz, 55131 Mainz, Germany.
Straub BK; Institute of Pathology, University Medical Center of the Johannes Gutenberg-University Mainz, 55131 Mainz, Germany.
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Źródło :
Cancers [Cancers (Basel)] 2022 Jun 23; Vol. 14 (13). Date of Electronic Publication: 2022 Jun 23.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Role of integrins in the metastatic spread of high-grade serous ovarian cancer.
Autorzy :
Krajnak S; Department of Gynecology and Obstetrics, University Medical Center Mainz, Mainz, Germany. .
Jäkel J; Department of Pathology, University Medical Center Mainz, Mainz, Germany.
Anić K; Department of Gynecology and Obstetrics, University Medical Center Mainz, Mainz, Germany.
Schwab R; Department of Gynecology and Obstetrics, University Medical Center Mainz, Mainz, Germany.
Schmidt M; Department of Gynecology and Obstetrics, University Medical Center Mainz, Mainz, Germany.
Hasenburg A; Department of Gynecology and Obstetrics, University Medical Center Mainz, Mainz, Germany.
Roth W; Department of Pathology, University Medical Center Mainz, Mainz, Germany.
Brenner W; Department of Gynecology and Obstetrics, University Medical Center Mainz, Mainz, Germany.
Battista MJ; Department of Gynecology and Obstetrics, University Medical Center Mainz, Mainz, Germany.
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Źródło :
Archives of gynecology and obstetrics [Arch Gynecol Obstet] 2022 May; Vol. 305 (5), pp. 1291-1298. Date of Electronic Publication: 2021 Oct 24.
Typ publikacji :
Journal Article
MeSH Terms :
Integrins*
Ovarian Neoplasms*/pathology
Female ; Humans ; Integrin alpha2 ; Integrin alpha4 ; Prognosis
Czasopismo naukowe
Tytuł :
Senescence-Associated Molecules and Tumor-Immune-Interactions as Prognostic Biomarkers in Colorectal Cancer.
Autorzy :
Kellers F; Institute of Pathology, University Medical Center Mainz, Mainz, Germany.
Fernandez A; Institute of Pathology, University Medical Center Mainz, Mainz, Germany.
Konukiewitz B; Institute of Pathology, Christian-Albrecht University of Kiel, Kiel, Germany.
Schindeldecker M; Institute of Pathology, University Medical Center Mainz, Mainz, Germany.
Tagscherer KE; Institute of Pathology, University Medical Center Mainz, Mainz, Germany.
Heintz A; Department of General, Visceral and Vascular Surgery, Catholic Hospital Mainz, Mainz, Germany.
Jesinghaus M; Department of Pathology, University Hospital Marburg, Marburg, Germany.
Roth W; Institute of Pathology, University Medical Center Mainz, Mainz, Germany.
Foersch S; Institute of Pathology, University Medical Center Mainz, Mainz, Germany.
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Źródło :
Frontiers in medicine [Front Med (Lausanne)] 2022 Apr 12; Vol. 9, pp. 865230. Date of Electronic Publication: 2022 Apr 12 (Print Publication: 2022).
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Value of c-MET and Associated Signaling Elements for Predicting Outcomes and Targeted Therapy in Penile Cancer.
Autorzy :
Thomas A; Department of Urology and Pediatric Urology, University Medicine Mainz, 55131 Mainz, Germany.
Slade KS; Department of Urology and Pediatric Urology, University Medicine Mainz, 55131 Mainz, Germany.
Blaheta RA; Department of Urology and Pediatric Urology, University Medicine Mainz, 55131 Mainz, Germany.
Markowitsch SD; Department of Urology and Pediatric Urology, University Medicine Mainz, 55131 Mainz, Germany.
Stenzel P; Department of Pathology, University Medicine Mainz, 55131 Mainz, Germany.
Tagscherer KE; Department of Pathology, University Medicine Mainz, 55131 Mainz, Germany.
Roth W; Department of Pathology, University Medicine Mainz, 55131 Mainz, Germany.
Schindeldecker M; Department of Pathology, University Medicine Mainz, 55131 Mainz, Germany.
Michaelis M; Industrial Biotechnology Centre, School of Biosciences, University of Kent, Canterbury CT2 7NJ, UK.
Rothweiler F; Institute of Medical Virology, Goethe-University, 60596 Frankfurt am Main, Germany.; Dr. Petra Joh-Forschungshaus, 60528 Frankfurt am Main, Germany.
Cinatl J; Institute of Medical Virology, Goethe-University, 60596 Frankfurt am Main, Germany.
Dotzauer R; Department of Urology and Pediatric Urology, University Medicine Mainz, 55131 Mainz, Germany.
Vakhrusheva O; Department of Urology and Pediatric Urology, University Medicine Mainz, 55131 Mainz, Germany.
Albersen M; Department of Urology, University Hospitals Leuven, 28046 Leuven, Belgium.
Haferkamp A; Department of Urology and Pediatric Urology, University Medicine Mainz, 55131 Mainz, Germany.
Juengel E; Department of Urology and Pediatric Urology, University Medicine Mainz, 55131 Mainz, Germany.
Cinatl J Jr; Institute of Medical Virology, Goethe-University, 60596 Frankfurt am Main, Germany.; Dr. Petra Joh-Forschungshaus, 60528 Frankfurt am Main, Germany.
Tsaur I; Department of Urology and Pediatric Urology, University Medicine Mainz, 55131 Mainz, Germany.
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Źródło :
Cancers [Cancers (Basel)] 2022 Mar 25; Vol. 14 (7). Date of Electronic Publication: 2022 Mar 25.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
ARAF suppresses ERBB3 expression and metastasis in a subset of lung cancers.
Autorzy :
Mooz J; Cell Biology Unit, University Medical Center of the Johannes Gutenberg University Mainz, 55131 Mainz, Germany.
Riegel K; Cell Biology Unit, University Medical Center of the Johannes Gutenberg University Mainz, 55131 Mainz, Germany.
Ps H; Division of Molecular Pathology, The Institute of Cancer Research, London, UK.
Sadanandam A; Division of Molecular Pathology, The Institute of Cancer Research, London, UK.
Marini F; Institute of Medical Biostatistics, Epidemiology and Informatics, University Medical Center of the Johannes Gutenberg University Mainz, 55131 Mainz, Germany.; Center for Thrombosis and Hemostasis (CTH), University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany.
Klein M; Institute of Immunology, University Medical Center of the Johannes Gutenberg University Mainz, 55131 Mainz, Germany.
Werner U; Indivumed GmbH, Hamburg, Germany.
Roth W; Institute of Pathology, University Medical Center of the Johannes Gutenberg University Mainz, 55131 Mainz, Germany.
Wilken-Schmitz A; Institute of Clinical Pharmacology, Goethe-University, Medical Faculty, Frankfurt (Main), Germany.
Tegeder I; Institute of Clinical Pharmacology, Goethe-University, Medical Faculty, Frankfurt (Main), Germany.
Rajalingam K; Cell Biology Unit, University Medical Center of the Johannes Gutenberg University Mainz, 55131 Mainz, Germany.; University Cancer Center Mainz, University Medical Center Mainz, Mainz, Germany.
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Źródło :
Science advances [Sci Adv] 2022 Mar 18; Vol. 8 (11), pp. eabk1538. Date of Electronic Publication: 2022 Mar 18.
Typ publikacji :
Journal Article
MeSH Terms :
Lung Neoplasms*/genetics
raf Kinases*/metabolism
Humans ; Protein Serine-Threonine Kinases ; Receptor, ErbB-3/genetics ; Receptor, ErbB-3/metabolism ; Signal Transduction
Czasopismo naukowe
Tytuł :
Comprehensive clinicopathologic study of alpha fetoprotein-expression in a large cohort of patients with hepatocellular carcinoma.
Autorzy :
Ridder DA; Institute of Pathology, University Medical Center of the Johannes Gutenberg University, Mainz, Germany.
Weinmann A; Department of Internal Medicine, University Medical Center of the Johannes Gutenberg University, Mainz, Germany.
Schindeldecker M; Institute of Pathology, University Medical Center of the Johannes Gutenberg University, Mainz, Germany.; Tissue Biobank, University Medical Center of the Johannes Gutenberg University, Mainz, Germany.
Urbansky LL; Institute of Pathology, University Medical Center of the Johannes Gutenberg University, Mainz, Germany.
Berndt K; Institute of Pathology, University Medical Center of the Johannes Gutenberg University, Mainz, Germany.
Gerber TS; Institute of Pathology, University Medical Center of the Johannes Gutenberg University, Mainz, Germany.
Lang H; Department of General, Visceral and Transplant Surgery, University Medical Center of the Johannes Gutenberg University, Mainz, Germany.
Lotz J; Institute for Laboratory Medicine and Clinical Chemistry, University Medical Center of the Johannes Gutenberg University, Mainz, Germany.
Lackner KJ; Institute for Laboratory Medicine and Clinical Chemistry, University Medical Center of the Johannes Gutenberg University, Mainz, Germany.
Roth W; Institute of Pathology, University Medical Center of the Johannes Gutenberg University, Mainz, Germany.
Straub BK; Institute of Pathology, University Medical Center of the Johannes Gutenberg University, Mainz, Germany.
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Źródło :
International journal of cancer [Int J Cancer] 2022 Mar 15; Vol. 150 (6), pp. 1053-1066. Date of Electronic Publication: 2021 Dec 18.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Carcinoma, Hepatocellular/*pathology
Liver Neoplasms/*pathology
alpha-Fetoproteins/*analysis
Adult ; Aged ; Carcinoma, Hepatocellular/chemistry ; Carcinoma, Hepatocellular/mortality ; Cohort Studies ; Female ; Humans ; Immunohistochemistry ; Liver Neoplasms/chemistry ; Liver Neoplasms/mortality ; Male ; Middle Aged
Czasopismo naukowe
Tytuł :
[Two new sections: "Molecular Tumor Board" and "Picture of the Month"].
Autorzy :
Roth W; Institut für Pathologie, Universitätsmedizin, Johannes Gutenberg-Universität Mainz, Langenbeckstr. 1, 55131, Mainz, Deutschland. wilfried.roth@unimedizin-mainz.de.
Gaida M; Institut für Pathologie, Universitätsmedizin, Johannes Gutenberg-Universität Mainz, Langenbeckstr. 1, 55131, Mainz, Deutschland.
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Transliterated Title :
Zwei neue Rubriken: „Molekulares Tumorboard“ und „Bild des Monats“.
Źródło :
Der Pathologe [Pathologe] 2022 Feb; Vol. 43 (1), pp. 1. Date of Electronic Publication: 2022 Jan 25.
Typ publikacji :
Editorial
Opinia redakcyjna
Tytuł :
Diffusion kernel-based predictive modeling of KRAS dependency in KRAS wild type cancer cell lines.
Autorzy :
Ulmer B; Institute of Pathology, Cologne University Hospital, Cologne, Germany. .
Odenthal M; Institute of Pathology, Cologne University Hospital, Cologne, Germany.
Buettner R; Institute of Pathology, Cologne University Hospital, Cologne, Germany.
Roth W; Institute of Pathology, Mainz University Hospital, Mainz, Germany.
Kloth M; Institute of Pathology, Mainz University Hospital, Mainz, Germany.
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Źródło :
NPJ systems biology and applications [NPJ Syst Biol Appl] 2022 Jan 19; Vol. 8 (1), pp. 2. Date of Electronic Publication: 2022 Jan 19.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Neoplasms*/genetics
Proto-Oncogene Proteins p21(ras)*/genetics
Proto-Oncogene Proteins p21(ras)*/metabolism
Cell Line ; Humans ; Mutation/genetics ; ras Proteins/genetics
Czasopismo naukowe
Tytuł :
Transforming Growth Factor-β Activated Kinase 1 (Tak1) Is Activated in Hepatocellular Carcinoma, Mediates Tumor Progression, and Predicts Unfavorable Outcome.
Autorzy :
Ridder DA; Institute of Pathology, University Medical Center of the Johannes Gutenberg University, 55131 Mainz, Germany.
Urbansky LL; Institute of Pathology, University Medical Center of the Johannes Gutenberg University, 55131 Mainz, Germany.
Witzel HR; Institute of Pathology, University Medical Center of the Johannes Gutenberg University, 55131 Mainz, Germany.
Schindeldecker M; Institute of Pathology, University Medical Center of the Johannes Gutenberg University, 55131 Mainz, Germany.; Tissue Biobank, University Medical Center of the Johannes Gutenberg University, 55131 Mainz, Germany.
Weinmann A; Department of Internal Medicine, University Medical Center of the Johannes Gutenberg University, 55131 Mainz, Germany.
Berndt K; Institute of Pathology, University Medical Center of the Johannes Gutenberg University, 55131 Mainz, Germany.
Gerber TS; Institute of Pathology, University Medical Center of the Johannes Gutenberg University, 55131 Mainz, Germany.
Köhler BC; Department of Medical Oncology, National Center for Tumor Diseases, University Hospital Heidelberg, 69120 Heidelberg, Germany.
Nichetti F; Medical Oncology Department, Fondazione IRCCS Istituto Nazionale dei Tumori di Milano, 20133 Milan, Italy.; Computational Oncology, Molecular Diagnostics Program, National Center for Tumor Diseases (NCT) and German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany.
Ludt A; Institute of Medical Biostatistics, Epidemiology, and Informatics (IMBEI), University Medical Center Mainz, 55131 Mainz, Germany.
Gehrke N; Department of Internal Medicine, University Medical Center of the Johannes Gutenberg University, 55131 Mainz, Germany.
Schattenberg JM; Department of Internal Medicine, University Medical Center of the Johannes Gutenberg University, 55131 Mainz, Germany.
Heinrich S; Department of General, Visceral and Transplant Surgery, University Medical Center of the Johannes Gutenberg University, 55131 Mainz, Germany.
Roth W; Institute of Pathology, University Medical Center of the Johannes Gutenberg University, 55131 Mainz, Germany.
Straub BK; Institute of Pathology, University Medical Center of the Johannes Gutenberg University, 55131 Mainz, Germany.
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Źródło :
Cancers [Cancers (Basel)] 2022 Jan 15; Vol. 14 (2). Date of Electronic Publication: 2022 Jan 15.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
German S3 Evidence-Based Guidelines on Focal Therapy in Localized Prostate Cancer: The First Evidence-Based Guidelines on Focal Therapy.
Autorzy :
Borkowetz A; German Society of Urology (DGU), Berlin, Germany.; Working Group of Focal and Microtherapy of the German Society of Urology (DGU), Berlin, Germany.; Department of Urology, University Hospital, Technische Universität Dresden, Dresden, Germany.
Blana A; German Society of Urology (DGU), Berlin, Germany.; Working Group of Focal and Microtherapy of the German Society of Urology (DGU), Berlin, Germany.; Department of Urology, Fuerth Hospital, Fuerth, Germany.
Böhmer D; Working Group Radiooncology German Cancer Society (ARO), Berlin, Germany.; Department of Radiooncology, University Hospital, Charite Berlin, Berlin, Germany.
Cash H; Working Group of Focal and Microtherapy of the German Society of Urology (DGU), Berlin, Germany.; ProUro, Berlin, Germany.; Department of Urology, University Hospital Magdeburg, Magdeburg, Germany.
Ehrmann U; Bundesverband Prostatakrebshilfe (BPS), Würzburg, Germany.
Franiel T; Working Group of Focal and Microtherapy of the German Society of Urology (DGU), Berlin, Germany.; German Röntgen Society, Berlin, Germany.; Department of Diagnostic and Interventional Radiology, University Hospital Jena, Jena, Germany.
Henkel TO; German Society of Urology (DGU), Berlin, Germany.; Working Group of Focal and Microtherapy of the German Society of Urology (DGU), Berlin, Germany.; Urologie Praxis, Berlin, Germany.
Höcht S; Working Group Radiooncology German Cancer Society (ARO), Berlin, Germany.; Xcare Praxis für Strahlentherapie, Saarlouis, Germany.
Kristiansen G; German Society of Pathology, Berlin, Germany.; Bundesverband Deutscher Urologen, Berlin, Germany.; Department of Pathology, Universitätsklinikum Bonn, Bonn, Germany.
Machtens S; German Society of Urology (DGU), Berlin, Germany.; Working Group of Focal and Microtherapy of the German Society of Urology (DGU), Berlin, Germany.; Department of Urology, GFO Hospitals Rhein-Berg, Marien-Hospital, Bergisch-Gladbach, Germany.
Niehoff P; Berufsverband Deutscher Strahlentherapeuten, Berlin, Germany.; Department of Radiooncology, Sana Hospital Offenbach, Offenbach, Germany.
Penzkofer T; Working Group of Focal and Microtherapy of the German Society of Urology (DGU), Berlin, Germany.; Department of Radiology, University Hospital Charite Berlin, Berlin, Germany.
Pinkawa M; Berufsverband Deutscher Strahlentherapeuten, Berlin, Germany.; Department of Radiooncology, MediClin Robert Janker Hospital, Bonn, Germany.
Radtke JP; Working Group of Focal and Microtherapy of the German Society of Urology (DGU), Berlin, Germany.; Department of Urology, University Hospital Essen, Essen, Germany.
Roth W; German Society of Pathology, Berlin, Germany.; Bundesverband Deutscher Urologen, Berlin, Germany.; Department of Pathology, University Hospital Mainz, Mainz, Germany.
Witzsch U; Working Group of Focal and Microtherapy of the German Society of Urology (DGU), Berlin, Germany.; Department of Urology, Krankenhaus Nordwest, Frankfurt, Germany.
Ganzer R; German Society of Urology (DGU), Berlin, Germany.; Department of Urology, Asklepios Hospital Bad Tölz, Bad Tölz, Germany.
Schlemmer HP; German Röntgen Society, Berlin, Germany.; Department of Radiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Grimm MO; German Society of Urology (DGU), Berlin, Germany.; Department of Urology, University Hospital Jena, Jena, Germany.
Hakenberg OW; German Society of Urology (DGU), Berlin, Germany.; Department of Urology, University Hospital Rostock, Rostock, Germany.
Schostak M; German Society of Urology (DGU), Berlin, Germany.; Working Group of Focal and Microtherapy of the German Society of Urology (DGU), Berlin, Germany.; Department of Urology, University Hospital Magdeburg, Magdeburg, Germany.
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Źródło :
Urologia internationalis [Urol Int] 2022; Vol. 106 (5), pp. 431-439. Date of Electronic Publication: 2022 Feb 10.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Prostatic Neoplasms*/diagnosis
Prostatic Neoplasms*/therapy
Cryotherapy ; Humans ; Male ; Prospective Studies
Czasopismo naukowe
Tytuł :
Interassay and interobserver comparability study of four programmed death-ligand 1 (PD-L1) immunohistochemistry assays in triple-negative breast cancer.
Autorzy :
Noske A; Institute of Pathology, School of Medicine, Technical University of Munich, Munich, Germany. Electronic address: .
Wagner DC; Institute of Pathology, University Medical Centre, Johannes Gutenberg University Mainz, Mainz, Germany.
Schwamborn K; Institute of Pathology, School of Medicine, Technical University of Munich, Munich, Germany.
Foersch S; Institute of Pathology, University Medical Centre, Johannes Gutenberg University Mainz, Mainz, Germany.
Steiger K; Institute of Pathology, School of Medicine, Technical University of Munich, Munich, Germany.
Kiechle M; Department of Gynaecology and Obstetrics, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany.
Oettler D; MSD Sharp & Dohme GmbH, Haar, Germany.
Karapetyan S; Institute of General Practice and Health Services Research, School of Medicine, Technical University of Munich, Munich, Germany.
Hapfelmeier A; Institute of General Practice and Health Services Research, School of Medicine, Technical University of Munich, Munich, Germany; Institute of Medical Informatics, Statistics and Epidemiology, School of Medicine, Technical University of Munich, Munich, Germany.
Roth W; Institute of Pathology, University Medical Centre, Johannes Gutenberg University Mainz, Mainz, Germany.
Weichert W; Institute of Pathology, School of Medicine, Technical University of Munich, Munich, Germany.
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Źródło :
Breast (Edinburgh, Scotland) [Breast] 2021 Dec; Vol. 60, pp. 238-244. Date of Electronic Publication: 2021 Nov 06.
Typ publikacji :
Comparative Study; Journal Article
MeSH Terms :
Triple Negative Breast Neoplasms*/diagnosis
Immunohistochemistry/*methods
B7-H1 Antigen/analysis ; Biomarkers, Tumor/analysis ; Humans ; Reproducibility of Results
Czasopismo naukowe
Tytuł :
[Digital teaching in pathology: experiences from Mainz].
Autorzy :
Straub BK; Institut für Pathologie, Universitätsmedizin Mainz, Johannes Gutenberg-Universität Mainz, Langenbeckstr. 1, 55131, Mainz, Deutschland. .
Gerber TS; Institut für Pathologie, Universitätsmedizin Mainz, Johannes Gutenberg-Universität Mainz, Langenbeckstr. 1, 55131, Mainz, Deutschland. .
Buggenhagen H; Zentrale Lehrplattform, Rudolf Frey Lernklinik Mainz, Universitätsmedizin Mainz, Johannes Gutenberg-Universität Mainz, Langenbeckstr. 1, 55131, Mainz, Deutschland.
Jäger B; Institut für Pathologie, Universitätsmedizin Mainz, Johannes Gutenberg-Universität Mainz, Langenbeckstr. 1, 55131, Mainz, Deutschland.
Sommer C; Institut für Neuropathologie, Universitätsmedizin Mainz, Johannes-Gutenberg-Universität Mainz, Langenbeckstr. 1, 55131, Mainz, Deutschland.
Roth W; Institut für Pathologie, Universitätsmedizin Mainz, Johannes Gutenberg-Universität Mainz, Langenbeckstr. 1, 55131, Mainz, Deutschland.
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Transliterated Title :
Digitale Lehre in der Pathologie: Erfahrungen aus Mainz.
Źródło :
Der Pathologe [Pathologe] 2021 Dec; Vol. 42 (Suppl 2), pp. 142-148. Date of Electronic Publication: 2021 Nov 23.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Learning*
Pathology, Surgical*
Humans ; Microscopy ; Pandemics
Czasopismo naukowe
Tytuł :
Response to the Comment on "Extended Molecular Profiling Improves Stratification and Prediction of Survival After Resection of Colorectal Liver Metastases".
Autorzy :
Lang H; Department of General, Visceral and Transplantation Surgery, Universitätsmedizin Mainz.; Mainz, Germany.
Kloth M; Department of Pathology, Universitätsmedizin Mainz.; Mainz, Germany.
Moehler M; Department of Gastroenterology and Hepatology, Universitätsmedizin Mainz, Mainz, Germany.
Roth W; Department of Pathology, Universitätsmedizin.; Mainz, Mainz, Germany.
Baumgart J; Department of General, Visceral and Transplantation.; Surgery, Universitätsmedizin Mainz.; Mainz, Germany.
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Źródło :
Annals of surgery [Ann Surg] 2021 Dec 01; Vol. 274 (6), pp. e714.
Typ publikacji :
Letter; Comment
MeSH Terms :
Colorectal Neoplasms*/genetics
Colorectal Neoplasms*/surgery
Liver Neoplasms*/surgery
Hepatectomy ; Humans
Opinia redakcyjna
Tytuł :
Multimodal Deep Learning for Prognosis Prediction in Renal Cancer.
Autorzy :
Schulz S; Institute of Pathology, University Medical Center Mainz, Mainz, Germany.
Woerl AC; Institute of Pathology, University Medical Center Mainz, Mainz, Germany.; Institute of Computer Science, Johannes Gutenberg University Mainz, Mainz, Germany.
Jungmann F; Department of Diagnostic and Interventional Radiology, University Medical Center Mainz, Mainz, Germany.
Glasner C; Institute of Pathology, University Medical Center Mainz, Mainz, Germany.
Stenzel P; Institute of Pathology, University Medical Center Mainz, Mainz, Germany.
Strobl S; Institute of Pathology, University Medical Center Mainz, Mainz, Germany.
Fernandez A; Institute of Pathology, University Medical Center Mainz, Mainz, Germany.
Wagner DC; Institute of Pathology, University Medical Center Mainz, Mainz, Germany.
Haferkamp A; Department of Urology and Pediatric Urology, University Medical Center Mainz, Mainz, Germany.
Mildenberger P; Department of Diagnostic and Interventional Radiology, University Medical Center Mainz, Mainz, Germany.
Roth W; Institute of Pathology, University Medical Center Mainz, Mainz, Germany.
Foersch S; Institute of Pathology, University Medical Center Mainz, Mainz, Germany.
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Źródło :
Frontiers in oncology [Front Oncol] 2021 Nov 24; Vol. 11, pp. 788740. Date of Electronic Publication: 2021 Nov 24 (Print Publication: 2021).
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Knockout of the KH-Type Splicing Regulatory Protein Drives Glomerulonephritis in MRL-Fas Mice.
Autorzy :
Schmidtke L; Department of Pharmacology, University Medical Center, Johannes Gutenberg University Mainz, 55131 Mainz, Germany.
Meineck M; First Medical Department, University Medical Center, Johannes Gutenberg-University Mainz, 55131 Mainz, Germany.
Saurin S; Department of Pharmacology, University Medical Center, Johannes Gutenberg University Mainz, 55131 Mainz, Germany.; First Medical Department, University Medical Center, Johannes Gutenberg-University Mainz, 55131 Mainz, Germany.
Otten S; Department of Pharmacology, University Medical Center, Johannes Gutenberg University Mainz, 55131 Mainz, Germany.
Gather F; Department of Pharmacology, University Medical Center, Johannes Gutenberg University Mainz, 55131 Mainz, Germany.
Schrick K; Department of Pharmacology, University Medical Center, Johannes Gutenberg University Mainz, 55131 Mainz, Germany.
Käfer R; Department of Pharmacology, University Medical Center, Johannes Gutenberg University Mainz, 55131 Mainz, Germany.
Roth W; Institute of Pathology, University Medical Center, Johannes Gutenberg-University Mainz, 55131 Mainz, Germany.
Kleinert H; Department of Pharmacology, University Medical Center, Johannes Gutenberg University Mainz, 55131 Mainz, Germany.
Weinmann-Menke J; First Medical Department, University Medical Center, Johannes Gutenberg-University Mainz, 55131 Mainz, Germany.
Pautz A; Department of Pharmacology, University Medical Center, Johannes Gutenberg University Mainz, 55131 Mainz, Germany.
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Źródło :
Cells [Cells] 2021 Nov 14; Vol. 10 (11). Date of Electronic Publication: 2021 Nov 14.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Glomerulonephritis/*pathology
RNA-Binding Proteins/*metabolism
Trans-Activators/*metabolism
Animals ; Biomarkers/metabolism ; CD11a Antigen/metabolism ; Chemokines/metabolism ; Female ; Kidney/pathology ; Lymph Nodes/pathology ; Male ; Mice, Inbred C57BL ; Mice, Inbred MRL lpr ; Mice, Knockout ; RNA, Messenger/genetics ; RNA, Messenger/metabolism
Czasopismo naukowe
Tytuł :
Epithelial-to-Mesenchymal Transition in Pancreatic Cancer is associated with Restricted Water Diffusion in Diffusion-Weighted Magnetic Resonance Imaging.
Autorzy :
Mayer P; Clinic for Diagnostic and Interventional Radiology, Heidelberg University Hospital, 69120 Heidelberg, Germany.
Kraft A; Institute of Pathology, University Medical Center Mainz, JGU-Mainz, 55131 Mainz, Germany.
Roth W; Institute of Pathology, University Medical Center Mainz, JGU-Mainz, 55131 Mainz, Germany.
Hackert T; Department of General, Visceral, and Transplantation Surgery, Heidelberg University Hospital, 69120 Heidelberg, Germany.
Bergmann F; Institute of Pathology, Heidelberg University Hospital, 69120 Heidelberg, Germany.; Clinical Pathology, Klinikum Darmstadt GmbH, 64283 Darmstadt, Germany.
Kauczor HU; Clinic for Diagnostic and Interventional Radiology, Heidelberg University Hospital, 69120 Heidelberg, Germany.
Steinle V; Clinic for Diagnostic and Interventional Radiology, Heidelberg University Hospital, 69120 Heidelberg, Germany.
Khristenko E; Clinic for Diagnostic and Interventional Radiology, Heidelberg University Hospital, 69120 Heidelberg, Germany.
Klauss M; Clinic for Diagnostic and Interventional Radiology, Heidelberg University Hospital, 69120 Heidelberg, Germany.
Gaida MM; Institute of Pathology, University Medical Center Mainz, JGU-Mainz, 55131 Mainz, Germany.; Research Center for Immunotherapy, University Medical Center Mainz, JGU-Mainz, 55131 Mainz, Germany.; Joint Unit Immunopathology, Institute of Pathology, University Medical Center, JGU-Mainz and TRON, Translational Oncology at the University Medical Center, JGU-Mainz, 55131 Mainz, Germany.
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Źródło :
Journal of Cancer [J Cancer] 2021 Nov 04; Vol. 12 (24), pp. 7488-7497. Date of Electronic Publication: 2021 Nov 04 (Print Publication: 2021).
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Nivolumab Reduces PD1 Expression and Alters Density and Proliferation of Tumor Infiltrating Immune Cells in a Tissue Slice Culture Model of Renal Cell Carcinoma.
Autorzy :
Stenzel PJ; Institute of Pathology, University Medical Center Mainz, 55131 Mainz, Germany.
Hörner N; Institute of Pathology, University Medical Center Mainz, 55131 Mainz, Germany.
Foersch S; Institute of Pathology, University Medical Center Mainz, 55131 Mainz, Germany.
Wagner DC; Institute of Pathology, University Medical Center Mainz, 55131 Mainz, Germany.
Tsaur I; Department of Urology, University Medical Center Mainz, 55131 Mainz, Germany.
Thomas A; Department of Urology, University Medical Center Mainz, 55131 Mainz, Germany.
Haferkamp A; Department of Urology, University Medical Center Mainz, 55131 Mainz, Germany.
Macher-Goeppinger S; Institute of Pathology, University Medical Center Mainz, 55131 Mainz, Germany.
Roth W; Institute of Pathology, University Medical Center Mainz, 55131 Mainz, Germany.
Porubsky S; Institute of Pathology, University Medical Center Mainz, 55131 Mainz, Germany.
Tagscherer KE; Institute of Pathology, University Medical Center Mainz, 55131 Mainz, Germany.
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Źródło :
Cancers [Cancers (Basel)] 2021 Sep 08; Vol. 13 (18). Date of Electronic Publication: 2021 Sep 08.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Cancer gene related characterization of patterns and point of recurrence after resection of colorectal liver metastases.
Autorzy :
Lang H; Department of General, Visceral and Transplantation Surgery, Universitätsmedizin Mainz, Mainz, Germany.
Baumgart J; Department of General, Visceral and Transplantation Surgery, Universitätsmedizin Mainz, Mainz, Germany.
Roth W; Department of Pathology, Universitätsmedizin Mainz, Mainz, Germany.
Moehler M; Department of Gastroenterology and Hepatology, Universitätsmedizin Mainz, Mainz, Germany.
Kloth M; Department of Pathology, Universitätsmedizin Mainz, Mainz, Germany.
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Źródło :
Annals of translational medicine [Ann Transl Med] 2021 Sep; Vol. 9 (17), pp. 1372.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Comparative analysis of nuclear and mitochondrial DNA from tissue and liquid biopsies of colorectal cancer patients.
Autorzy :
Haupts A; Institute of Pathology, University Medical Center JGU Mainz, Langenbeckstraße 1, 55131, Mainz, Germany. .
Vogel A; Institute of Pathology, University Medical Center JGU Mainz, Langenbeckstraße 1, 55131, Mainz, Germany.
Foersch S; Institute of Pathology, University Medical Center JGU Mainz, Langenbeckstraße 1, 55131, Mainz, Germany.
Hartmann M; Department of Internal Medicine I, University Medical Center JGU Mainz, Langenbeckstraße 1, 55131, Mainz, Germany.
Maderer A; Department of Internal Medicine I, University Medical Center JGU Mainz, Langenbeckstraße 1, 55131, Mainz, Germany.
Wachter N; Department of General, Visceral and Transplantation Surgery, University Medical Center JGU Mainz, Langenbeckstraße 1, 55131, Mainz, Germany.
Huber T; Department of General, Visceral and Transplantation Surgery, University Medical Center JGU Mainz, Langenbeckstraße 1, 55131, Mainz, Germany.
Kneist W; Department of General, Visceral and Transplantation Surgery, University Medical Center JGU Mainz, Langenbeckstraße 1, 55131, Mainz, Germany.; Department of General and Visceral Surgery, St. Georg Hospital Eisenach gGmbH, Mühlhäuser Straße 94, 99817, Eisenach, Germany.
Roth W; Institute of Pathology, University Medical Center JGU Mainz, Langenbeckstraße 1, 55131, Mainz, Germany.
Lang H; Department of General, Visceral and Transplantation Surgery, University Medical Center JGU Mainz, Langenbeckstraße 1, 55131, Mainz, Germany.
Moehler M; Department of Internal Medicine I, University Medical Center JGU Mainz, Langenbeckstraße 1, 55131, Mainz, Germany.
Hartmann N; Institute of Pathology, University Medical Center JGU Mainz, Langenbeckstraße 1, 55131, Mainz, Germany. .
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Źródło :
Scientific reports [Sci Rep] 2021 Aug 18; Vol. 11 (1), pp. 16745. Date of Electronic Publication: 2021 Aug 18.
Typ publikacji :
Clinical Trial; Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
High-Throughput Nucleotide Sequencing*
Colorectal Neoplasms/*genetics
DNA, Mitochondrial/*genetics
DNA, Neoplasm/*genetics
Adult ; Aged ; Aged, 80 and over ; Colorectal Neoplasms/pathology ; Female ; Humans ; Liquid Biopsy ; Male ; Middle Aged
Czasopismo naukowe
Tytuł :
Clinicopathological Significance of Syndecan-1 in Cholangiocarcinoma: A Study Based on Immunohistochemistry and Public Sequencing Data.
Autorzy :
Gerber TS; Institute of Pathology, University Medical Center of the Johannes Gutenberg-University Mainz, 55131 Mainz, Germany.
Bartsch F; Department of General, Visceral and Transplant Surgery, University Medical Center of the Johannes Gutenberg-University Mainz, 55131 Mainz, Germany.
Wagner DC; Institute of Pathology, University Medical Center of the Johannes Gutenberg-University Mainz, 55131 Mainz, Germany.
Schindeldecker M; Institute of Pathology, University Medical Center of the Johannes Gutenberg-University Mainz, 55131 Mainz, Germany.; Tissue Biobank, University Medical Center of the Johannes Gutenberg-University Mainz, 55131 Mainz, Germany.
Heuft LK; Department of General, Visceral and Transplant Surgery, University Medical Center of the Johannes Gutenberg-University Mainz, 55131 Mainz, Germany.
Roth W; Institute of Pathology, University Medical Center of the Johannes Gutenberg-University Mainz, 55131 Mainz, Germany.
Lang H; Department of General, Visceral and Transplant Surgery, University Medical Center of the Johannes Gutenberg-University Mainz, 55131 Mainz, Germany.
Straub BK; Institute of Pathology, University Medical Center of the Johannes Gutenberg-University Mainz, 55131 Mainz, Germany.
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Źródło :
Journal of clinical medicine [J Clin Med] 2021 Jun 22; Vol. 10 (13). Date of Electronic Publication: 2021 Jun 22.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
SWI/SNF-deficient undifferentiated/rhabdoid carcinoma of the gallbladder carrying a POLE mutation in a 30-year-old woman: a case report.
Autorzy :
Gerber TS; Institute of Pathology, University Medical Center Mainz, Langenbeckstraße 1, 55131, Mainz, Germany.
Agaimy A; Institute of Pathology, Erlangen University Hospital, Erlangen, Germany.
Hartmann A; Institute of Pathology, Erlangen University Hospital, Erlangen, Germany.
Habekost M; Department of General- and Visceral Surgery, Agaplesion Markus Krankenhaus, Frankfurt am Main, Germany.
Roth W; Institute of Pathology, University Medical Center Mainz, Langenbeckstraße 1, 55131, Mainz, Germany.
Stenzinger A; Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany.
Schirmacher P; Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany.
Straub BK; Institute of Pathology, University Medical Center Mainz, Langenbeckstraße 1, 55131, Mainz, Germany. .
Pokaż więcej
Źródło :
Diagnostic pathology [Diagn Pathol] 2021 Jun 12; Vol. 16 (1), pp. 52. Date of Electronic Publication: 2021 Jun 12.
Typ publikacji :
Case Reports
MeSH Terms :
Biomarkers, Tumor*/deficiency
Biomarkers, Tumor*/genetics
Mutation*
Chromosomal Proteins, Non-Histone/*deficiency
DNA Polymerase II/*genetics
Gallbladder Neoplasms/*pathology
Poly-ADP-Ribose Binding Proteins/*genetics
Rhabdoid Tumor/*pathology
Transcription Factors/*deficiency
Adult ; Cell Differentiation ; DNA Mutational Analysis ; DNA-Binding Proteins/deficiency ; Fatal Outcome ; Female ; Gallbladder Neoplasms/chemistry ; Gallbladder Neoplasms/genetics ; Gallbladder Neoplasms/surgery ; Genetic Predisposition to Disease ; High-Throughput Nucleotide Sequencing ; Humans ; Immunohistochemistry ; Phenotype ; Rhabdoid Tumor/chemistry ; Rhabdoid Tumor/genetics ; Rhabdoid Tumor/surgery ; Treatment Outcome
Raport

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