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Tytuł :
Discovery of 4-(3-aminopyrrolidinyl)-3-aryl-5-(benzimidazol-2-yl)-pyridines as potent and selective SST5 agonists for the treatment of congenital hyperinsulinism.
Autorzy :
Zhao J; Crinetics Pharmaceuticals, Inc., 10222 Barnes Canyon Road, San Diego, CA 92121, United States. Electronic address: .
Wang S; Crinetics Pharmaceuticals, Inc., 10222 Barnes Canyon Road, San Diego, CA 92121, United States.
Hee Kim S; Crinetics Pharmaceuticals, Inc., 10222 Barnes Canyon Road, San Diego, CA 92121, United States.
Han S; Crinetics Pharmaceuticals, Inc., 10222 Barnes Canyon Road, San Diego, CA 92121, United States.
Rico-Bautista E; Crinetics Pharmaceuticals, Inc., 10222 Barnes Canyon Road, San Diego, CA 92121, United States.
Sturchler E; Crinetics Pharmaceuticals, Inc., 10222 Barnes Canyon Road, San Diego, CA 92121, United States.
Nguyen J; Crinetics Pharmaceuticals, Inc., 10222 Barnes Canyon Road, San Diego, CA 92121, United States.
Tan H; Crinetics Pharmaceuticals, Inc., 10222 Barnes Canyon Road, San Diego, CA 92121, United States.
Staley C; Crinetics Pharmaceuticals, Inc., 10222 Barnes Canyon Road, San Diego, CA 92121, United States.
Karin Kusnetzow A; Crinetics Pharmaceuticals, Inc., 10222 Barnes Canyon Road, San Diego, CA 92121, United States.
Betz SF; Crinetics Pharmaceuticals, Inc., 10222 Barnes Canyon Road, San Diego, CA 92121, United States.
Johns M; Crinetics Pharmaceuticals, Inc., 10222 Barnes Canyon Road, San Diego, CA 92121, United States.
Goulet L; Crinetics Pharmaceuticals, Inc., 10222 Barnes Canyon Road, San Diego, CA 92121, United States.
Luo R; Crinetics Pharmaceuticals, Inc., 10222 Barnes Canyon Road, San Diego, CA 92121, United States.
Fowler M; Crinetics Pharmaceuticals, Inc., 10222 Barnes Canyon Road, San Diego, CA 92121, United States.
Athanacio J; Crinetics Pharmaceuticals, Inc., 10222 Barnes Canyon Road, San Diego, CA 92121, United States.
Markison S; Crinetics Pharmaceuticals, Inc., 10222 Barnes Canyon Road, San Diego, CA 92121, United States.
Scott Struthers R; Crinetics Pharmaceuticals, Inc., 10222 Barnes Canyon Road, San Diego, CA 92121, United States.
Zhu Y; Crinetics Pharmaceuticals, Inc., 10222 Barnes Canyon Road, San Diego, CA 92121, United States.
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Źródło :
Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2022 Sep 01; Vol. 71, pp. 128807. Date of Electronic Publication: 2022 May 20.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Congenital Hyperinsulinism*/drug therapy
Somatostatin*/pharmacology
Somatostatin*/physiology
Animals ; Dogs ; Humans ; Male ; Pyridines/pharmacology ; Rats ; Rats, Sprague-Dawley ; Receptors, Somatostatin/agonists
Czasopismo naukowe
Tytuł :
In patients with well-differentiated neuroendocrine tumours, there is no apparent benefit of somatostatin analogues after disease control by peptide receptor radionuclide therapy.
Autorzy :
Syguła A; Department of Nuclear Medicine and Endocrine Oncology, Gliwice Branch, Maria Sklodowska-Curie National Research Institute of Oncology, Wybrzeże Armii Krajowej 16, 44-101, Gliwice, Poland.
Ledwon A; Department of Nuclear Medicine and Endocrine Oncology, Gliwice Branch, Maria Sklodowska-Curie National Research Institute of Oncology, Wybrzeże Armii Krajowej 16, 44-101, Gliwice, Poland.
Hasse-Lazar K; Department of Nuclear Medicine and Endocrine Oncology, Gliwice Branch, Maria Sklodowska-Curie National Research Institute of Oncology, Wybrzeże Armii Krajowej 16, 44-101, Gliwice, Poland.
Jurecka-Lubieniecka B; Department of Nuclear Medicine and Endocrine Oncology, Gliwice Branch, Maria Sklodowska-Curie National Research Institute of Oncology, Wybrzeże Armii Krajowej 16, 44-101, Gliwice, Poland.
Michalik B; Department of Nuclear Medicine and Endocrine Oncology, Gliwice Branch, Maria Sklodowska-Curie National Research Institute of Oncology, Wybrzeże Armii Krajowej 16, 44-101, Gliwice, Poland.
Paliczka-Cieślik E; Department of Nuclear Medicine and Endocrine Oncology, Gliwice Branch, Maria Sklodowska-Curie National Research Institute of Oncology, Wybrzeże Armii Krajowej 16, 44-101, Gliwice, Poland.
Zeman M; The Oncologic and Reconstructive Surgery Clinic, Gliwice Branch, Maria Sklodowska-Curie National Research Institute of Oncology, Gliwice, Poland.
Chmielik E; Tumor Pathology Department, Gliwice Branch, Maria Sklodowska-Curie National Research Institute of Oncology, Gliwice, Poland.
Sczasny J; Radiology and Diagnostic Imaging Department, Gliwice Branch, Maria Sklodowska-Curie National Research Institute of Oncology, Gliwice, Poland.
Jarzab B; Department of Nuclear Medicine and Endocrine Oncology, Gliwice Branch, Maria Sklodowska-Curie National Research Institute of Oncology, Wybrzeże Armii Krajowej 16, 44-101, Gliwice, Poland.
Handkiewicz-Junak D; Department of Nuclear Medicine and Endocrine Oncology, Gliwice Branch, Maria Sklodowska-Curie National Research Institute of Oncology, Wybrzeże Armii Krajowej 16, 44-101, Gliwice, Poland. .
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Źródło :
European journal of nuclear medicine and molecular imaging [Eur J Nucl Med Mol Imaging] 2022 Sep; Vol. 49 (11), pp. 3841-3851. Date of Electronic Publication: 2022 May 03.
Typ publikacji :
Journal Article; Randomized Controlled Trial
MeSH Terms :
Neuroendocrine Tumors*/pathology
Neuroendocrine Tumors*/radiotherapy
Somatostatin*/analogs & derivatives
Somatostatin*/therapeutic use
Humans ; Octreotide/therapeutic use ; Prospective Studies ; Radioisotopes ; Receptors, Somatostatin ; Retrospective Studies ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Epigenetic potentiation of somatostatin-2 by guadecitabine in neuroendocrine neoplasias as a novel method to allow delivery of peptide receptor radiotherapy.
Autorzy :
Evans JS; Department of Surgery and Cancer, Imperial College London, Hammersmith Campus, London, UK.
Beaumont J; Department of Surgery and Cancer, Imperial College London, Hammersmith Campus, London, UK.
Braga M; Department of Surgery and Cancer, Imperial College London, Hammersmith Campus, London, UK.
Masrour N; Department of Surgery and Cancer, Imperial College London, Hammersmith Campus, London, UK.
Mauri F; Department of Surgery and Cancer, Imperial College London, Hammersmith Campus, London, UK.
Beckley A; Department of Surgery and Cancer, Imperial College London, Hammersmith Campus, London, UK.
Butt S; Department of Surgery and Cancer, Imperial College London, Hammersmith Campus, London, UK.
Karali CS; Department of Surgery and Cancer, Imperial College London, Hammersmith Campus, London, UK.
Cawthorne C; Department of Biomedical Sciences, University of Hull, Hull, UK.
Archibald S; Department of Biomedical Sciences, University of Hull, Hull, UK.
Aboagye EO; Department of Surgery and Cancer, Imperial College London, Hammersmith Campus, London, UK.
Sharma R; Department of Surgery and Cancer, Imperial College London, Hammersmith Campus, London, UK. Electronic address: .
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Źródło :
European journal of cancer (Oxford, England : 1990) [Eur J Cancer] 2022 Nov; Vol. 176, pp. 110-120. Date of Electronic Publication: 2022 Oct 05.
Typ publikacji :
Journal Article
MeSH Terms :
Receptors, Somatostatin*/genetics
Receptors, Somatostatin*/metabolism
Neuroendocrine Tumors*/drug therapy
Neuroendocrine Tumors*/genetics
Neuroendocrine Tumors*/radiotherapy
Humans ; Azacitidine/pharmacology ; Epigenesis, Genetic ; Somatostatin ; Octreotide/therapeutic use
Czasopismo naukowe
Tytuł :
Structural insights into ligand recognition and selectivity of somatostatin receptors.
Autorzy :
Zhao W; State Key Laboratory of Drug Research and CAS Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.; University of Chinese Academy of Sciences, Beijing, China.
Han S; State Key Laboratory of Drug Research and CAS Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.; School of Pharmaceutical Science and Technology, Hangzhou Institute for Advanced Study, UCAS, Hangzhou, Zhejiang, China.
Qiu N; State Key Laboratory of Drug Research and CAS Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.; University of Chinese Academy of Sciences, Beijing, China.
Feng W; Department of Pharmacology, School of Basic Medical Sciences, Fudan University, Shanghai, China.
Lu M; State Key Laboratory of Drug Research and CAS Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.; University of Chinese Academy of Sciences, Beijing, China.
Zhang W; School of Chinese Materia Medica, Nanjing University of Chinese Medicine, Nanjing, Jiangsu, China.
Wang M; State Key Laboratory of Drug Research and CAS Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.; School of Life Science and Technology, ShanghaiTech University, Shanghai, China.
Zhou Q; Department of Pharmacology, School of Basic Medical Sciences, Fudan University, Shanghai, China.
Chen S; State Key Laboratory of Drug Research and CAS Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.; University of Chinese Academy of Sciences, Beijing, China.
Xu W; State Key Laboratory of Drug Research and CAS Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.; University of Chinese Academy of Sciences, Beijing, China.
Du J; State Key Laboratory of Drug Research and CAS Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.; School of Pharmaceutical Science and Technology, Hangzhou Institute for Advanced Study, UCAS, Hangzhou, Zhejiang, China.
Chu X; State Key Laboratory of Drug Research and CAS Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.
Yi C; State Key Laboratory of Drug Research and CAS Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.
Dai A; The National Center for Drug Screening, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.
Hu L; Amgen Asia R&D Center, Shanghai, China.
Shen MY; Amgen Asia R&D Center, Shanghai, China.
Sun Y; Amgen Asia R&D Center, Shanghai, China.
Zhang Q; Amgen Asia R&D Center, Shanghai, China.
Ma Y; Amgen Asia R&D Center, Shanghai, China.
Zhong W; Amgen Asia R&D Center, Shanghai, China.; Regor Therapeutics, Shanghai, China.
Yang D; State Key Laboratory of Drug Research and CAS Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China. .; University of Chinese Academy of Sciences, Beijing, China. .; The National Center for Drug Screening, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China. .
Wang MW; State Key Laboratory of Drug Research and CAS Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China. .; University of Chinese Academy of Sciences, Beijing, China. .; Department of Pharmacology, School of Basic Medical Sciences, Fudan University, Shanghai, China. .; School of Life Science and Technology, ShanghaiTech University, Shanghai, China. .; The National Center for Drug Screening, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China. .
Wu B; State Key Laboratory of Drug Research and CAS Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China. .; University of Chinese Academy of Sciences, Beijing, China. .; School of Pharmaceutical Science and Technology, Hangzhou Institute for Advanced Study, UCAS, Hangzhou, Zhejiang, China. .; School of Life Science and Technology, ShanghaiTech University, Shanghai, China. .
Zhao Q; State Key Laboratory of Drug Research and CAS Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China. .; University of Chinese Academy of Sciences, Beijing, China. .; School of Chinese Materia Medica, Nanjing University of Chinese Medicine, Nanjing, Jiangsu, China. .; Zhongshan Institute of Drug Discovery, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Zhongshan, Guangdong, China. .
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Źródło :
Cell research [Cell Res] 2022 Aug; Vol. 32 (8), pp. 761-772. Date of Electronic Publication: 2022 Jun 23.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Neoplasms*/metabolism
Receptors, Somatostatin*/agonists
Receptors, Somatostatin*/metabolism
Cryoelectron Microscopy ; Humans ; Ligands ; Somatostatin/metabolism ; Somatostatin/pharmacology ; Somatostatin/therapeutic use
Czasopismo naukowe
Tytuł :
Pulmonary neuroendocrine tumours and somatostatin receptor status: an assessment of unlicensed use of somatostatin analogues in the clinical practice.
Autorzy :
Kiesewetter B; Departments of Medicine I, Division of Oncology.
Mazal P; Departments of Pathology.
Kretschmer-Chott E; Departments of Biomedical Imaging and Image-guided Therapy, Division of Nuclear Medicine, Medical University of Vienna, Vienna, Austria.
Mayerhoefer ME; Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, USA; Department of Biomedical Imaging and Image-guided Therapy, Division of General and Paediatric Radiology, Medical University of Vienna, Vienna, Austria.
Raderer M; Departments of Medicine I, Division of Oncology. Electronic address: .
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Źródło :
ESMO open [ESMO Open] 2022 Jun; Vol. 7 (3), pp. 100478. Date of Electronic Publication: 2022 May 04.
Typ publikacji :
Journal Article
MeSH Terms :
Neuroendocrine Tumors*/drug therapy
Neuroendocrine Tumors*/pathology
Receptors, Somatostatin*/metabolism
Humans ; Positron Emission Tomography Computed Tomography ; Retrospective Studies ; Somatostatin/pharmacology ; Somatostatin/therapeutic use
Czasopismo naukowe
Tytuł :
Rechallenge With Additional Doses of 177 Lu-DOTATOC After Failure of Maintenance Therapy With Cold Somatostatin Analogs.
Autorzy :
Weich A; From the Internal Medicine II, Gastroenterology.
Werner RA
Serfling SE; Department of Nuclear Medicine, University Hospital Würzburg, Würzburg, Germany.
Solnes LB; The Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD.
Pomper MG; The Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD.
Buck AK; Department of Nuclear Medicine, University Hospital Würzburg, Würzburg, Germany.
Higuchi T
Rowe SP; The Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD.
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Źródło :
Clinical nuclear medicine [Clin Nucl Med] 2022 Aug 01; Vol. 47 (8), pp. 719-720. Date of Electronic Publication: 2022 Apr 19.
Typ publikacji :
Case Reports; Journal Article
MeSH Terms :
Neuroendocrine Tumors*/diagnostic imaging
Neuroendocrine Tumors*/drug therapy
Neuroendocrine Tumors*/radiotherapy
Somatostatin*/therapeutic use
Female ; Humans ; Middle Aged ; Octreotide/analogs & derivatives ; Octreotide/therapeutic use ; Radioisotopes ; Radiopharmaceuticals/therapeutic use ; Receptors, Somatostatin
Czasopismo naukowe
Tytuł :
Training on Reporting and Data System (RADS) for Somatostatin-Receptor Targeted Molecular Imaging Can Reduce the Test Anxiety of Inexperienced Readers.
Autorzy :
Weich A; Department of Internal Medicine II and ENETS Center of Excellence, Gastroenterology, University Hospital Würzburg, Würzburg, Germany.
Higuchi T; Department of Nuclear Medicine, University Hospital Würzburg, Würzburg, Germany.; Dentistry and Pharmaceutical Sciences, Okayama University Graduate School of Medicine, Okayama, Japan.
Bundschuh RA; Department of Nuclear Medicine, University Hospital Bonn, Bonn, Germany.
Lapa C; Nuclear Medicine, Medical Faculty, University of Augsburg, Augsburg, Germany.
Serfling SE; Department of Nuclear Medicine, University Hospital Würzburg, Würzburg, Germany.
Rowe SP; The Russell H Morgan Department of Radiology and Radiological Science, Division of Nuclear Medicine and Molecular Imaging, Johns Hopkins School of Medicine, Baltimore, MD, USA.
Pomper MG; The Russell H Morgan Department of Radiology and Radiological Science, Division of Nuclear Medicine and Molecular Imaging, Johns Hopkins School of Medicine, Baltimore, MD, USA.
Herrmann K; Department of Nuclear Medicine, University Hospital Essen, Essen, Germany.
Buck AK; Department of Nuclear Medicine, University Hospital Würzburg, Würzburg, Germany.
Derlin T; Department of Nuclear Medicine, Hannover Medical School, Hannover, Germany.
Werner RA; Department of Nuclear Medicine, University Hospital Würzburg, Würzburg, Germany. .; The Russell H Morgan Department of Radiology and Radiological Science, Division of Nuclear Medicine and Molecular Imaging, Johns Hopkins School of Medicine, Baltimore, MD, USA. .
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Źródło :
Molecular imaging and biology [Mol Imaging Biol] 2022 Aug; Vol. 24 (4), pp. 631-640. Date of Electronic Publication: 2022 Mar 01.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Receptors, Somatostatin*
Test Anxiety*
Humans ; Molecular Imaging ; Positron Emission Tomography Computed Tomography/methods ; Somatostatin
Czasopismo naukowe
Tytuł :
Pasireotide-resistant Refractory Cushing's Disease without Somatostatin Receptor 5 Expression.
Autorzy :
Mizuno T; Department of Endocrinolgy and Metabolism, Toranomon Hospital, Japan.
Inoshita N; Department of Pathology, Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology Hospital, Japan.; Department of Hypothalamic and Pituitary Surgery, Toranomon Hospital, Japan.
Fukuhara N; Department of Hypothalamic and Pituitary Surgery, Toranomon Hospital, Japan.
Tatsushima K; Department of Endocrinolgy and Metabolism, Toranomon Hospital, Japan.
Takeshita A; Department of Endocrinolgy and Metabolism, Toranomon Hospital, Japan.
Yamada S; Department of Hypothalamic and Pituitary Surgery, Toranomon Hospital, Japan.; Neurosurgery Center, Moriyama Memorial Hospital, Japan.
Nishioka H; Department of Hypothalamic and Pituitary Surgery, Toranomon Hospital, Japan.
Takeuchi Y; Department of Endocrinolgy and Metabolism, Toranomon Hospital, Japan.
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Źródło :
Internal medicine (Tokyo, Japan) [Intern Med] 2022 Mar 01; Vol. 61 (5), pp. 679-685. Date of Electronic Publication: 2021 Aug 31.
Typ publikacji :
Case Reports; Journal Article
MeSH Terms :
Pituitary ACTH Hypersecretion*/drug therapy
Pituitary ACTH Hypersecretion*/genetics
Receptors, Somatostatin*/genetics
Adult ; Humans ; Male ; Somatostatin/analogs & derivatives ; Somatostatin/therapeutic use
Czasopismo naukowe
Tytuł :
EANM dosimetry committee recommendations for dosimetry of 177Lu-labelled somatostatin-receptor- and PSMA-targeting ligands.
Autorzy :
Sjögreen Gleisner K; Medical Radiation Physics, Clinical Sciences Lund, Lund University, Lund, Sweden. katarina.sjogreen_.
Chouin N; Université de Nantes, CNRS, Inserm, Oniris, CRCINA, Nantes, France.
Gabina PM; Department of Medical Physics and Radiation Protection, Gurutzeta-Cruces University Hospital/Biocruces Health Research Institute, Barakaldo, Spain.; Department of Applied Physics, Faculty of Engineering, UPV/EHU, Bilbao, Spain.
Cicone F; Department of Experimental and Clinical Medicine, Neuroscience Research Centre, PET/RM Unit, 'Magna Graecia' University of Catanzaro, Catanzaro, Italy.; Nuclear Medicine Unit, University Hospital 'Mater Domini, Catanzaro, Italy.
Gnesin S; Institute of Radiation Physics, Lausanne University Hospital, University of Lausanne, Lausanne, Switzerland.
Stokke C; Division of Radiology and Nuclear Medicine, Oslo University Hospital, Oslo, Norway.; Department of Physics, University of Oslo, Oslo, Norway.
Konijnenberg M; Department of Radiology and Nuclear Medicine, Erasmus Medical Center, Rotterdam, the Netherlands.; Department of Medical Imaging, Radboud University Medical Center, Nijmegen, the Netherlands.
Cremonesi M; Radiation Research Unit, Department of Medical Imaging and Radiation Sciences, Istituto Europeo di Oncologia, IRCCS, Milan, Italy.
Verburg FA; Department of Radiology and Nuclear Medicine, Erasmus Medical Center, Rotterdam, the Netherlands.
Bernhardt P; Department of Medical Radiation Sciences, Institute of Clinical Sciences, Sahlgrenska Academy, Gothenburg University, Gothenburg, Sweden.; Department of Medical Physics and Biomedical Engineering, Sahlgrenska University Hospital, Gothenburg, Sweden.
Eberlein U; Department of Nuclear Medicine, University Hospital Würzburg, Würzburg, Germany.
Gear J; Joint department of Physics, Royal Marsden NHSFT and Institute of Cancer Research, Sutton, UK.
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Źródło :
European journal of nuclear medicine and molecular imaging [Eur J Nucl Med Mol Imaging] 2022 May; Vol. 49 (6), pp. 1778-1809. Date of Electronic Publication: 2022 Mar 14.
Typ publikacji :
Journal Article
MeSH Terms :
Radiation Injuries*
Receptors, Somatostatin*
Humans ; Ligands ; Lutetium/therapeutic use ; Male ; Prostate-Specific Antigen ; Radioisotopes ; Radiopharmaceuticals/adverse effects ; Somatostatin
Czasopismo naukowe
Tytuł :
Conversion of Gastrointestinal Somatostatin-Expressing D Cells Into Insulin-Producing Beta-Like Cells Upon Pax4 Misexpression.
Autorzy :
Garrido-Utrilla A; Université Côte d'Azur, Centre National de la Recherche Scientifique (CNRS), Institut National de la Santé Et de la Recherche Médicale (INSERM), Institut de Biologie Valrose (iBV), Nice, France.
Ayachi C; Université Côte d'Azur, Centre National de la Recherche Scientifique (CNRS), Institut National de la Santé Et de la Recherche Médicale (INSERM), Institut de Biologie Valrose (iBV), Nice, France.
Friano ME; Université Côte d'Azur, Centre National de la Recherche Scientifique (CNRS), Institut National de la Santé Et de la Recherche Médicale (INSERM), Institut de Biologie Valrose (iBV), Nice, France.
Atlija J; Department of Cryopreservation, Distribution, Typing and Animal Archiving, Centre National de la Recherche Scientifique-Unité d'Appui à la Recherche (CNRS-UAR) 44 Typage et Archivage d'Animaux Modèles (TAAM), Orléans, France.
Balaji S; PlantaCorp Gesellschaft mit beschränkter Haftung (GmbH), Hamburg, Germany.
Napolitano T; Université Côte d'Azur, Centre National de la Recherche Scientifique (CNRS), Institut National de la Santé Et de la Recherche Médicale (INSERM), Institut de Biologie Valrose (iBV), Nice, France.
Silvano S; Université Côte d'Azur, Centre National de la Recherche Scientifique (CNRS), Institut National de la Santé Et de la Recherche Médicale (INSERM), Institut de Biologie Valrose (iBV), Nice, France.
Druelle N; Columbia University College of Physicians & Surgeons, Department of Medicine, New York, NY, United States.
Collombat P; Université Côte d'Azur, Centre National de la Recherche Scientifique (CNRS), Institut National de la Santé Et de la Recherche Médicale (INSERM), Institut de Biologie Valrose (iBV), Nice, France.
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Źródło :
Frontiers in endocrinology [Front Endocrinol (Lausanne)] 2022 Apr 29; Vol. 13, pp. 861922. Date of Electronic Publication: 2022 Apr 29 (Print Publication: 2022).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Somatostatin-Secreting Cells*
Homeodomain Proteins/*metabolism
Paired Box Transcription Factors/*metabolism
Animals ; Homeodomain Proteins/genetics ; Insulin ; Mice ; Paired Box Transcription Factors/genetics ; Somatostatin/genetics
Czasopismo naukowe
Tytuł :
Epigenetic regulation of somatostatin and somatostatin receptors in neuroendocrine tumors and other types of cancer.
Autorzy :
Klomp MJ; Department of Internal Medicine, Division of Endocrinology, Erasmus MC, Rotterdam, The Netherlands.; Department of Radiology & Nuclear Medicine, Erasmus MC, Rotterdam, The Netherlands.
Dalm SU; Department of Radiology & Nuclear Medicine, Erasmus MC, Rotterdam, The Netherlands.
de Jong M; Department of Radiology & Nuclear Medicine, Erasmus MC, Rotterdam, The Netherlands.
Feelders RA; Department of Internal Medicine, Division of Endocrinology, Erasmus MC, Rotterdam, The Netherlands.
Hofland J; Department of Internal Medicine, Division of Endocrinology, Erasmus MC, Rotterdam, The Netherlands.
Hofland LJ; Department of Internal Medicine, Division of Endocrinology, Erasmus MC, Rotterdam, The Netherlands. .
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Źródło :
Reviews in endocrine & metabolic disorders [Rev Endocr Metab Disord] 2021 Sep; Vol. 22 (3), pp. 495-510. Date of Electronic Publication: 2020 Oct 21.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Neuroendocrine Tumors*/genetics
Receptors, Somatostatin*/genetics
Receptors, Somatostatin*/metabolism
Epigenesis, Genetic ; Humans ; Somatostatin
Czasopismo naukowe
Tytuł :
Somatostatin receptor ligands suppressed proliferation and lipogenesis in 3T3-L1 preadipocytes.
Autorzy :
Zhao Z; State Key Laboratory of Bioactive Substrate and Function of Natural Medicine, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.; Department of Pharmacy, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Gong F; Department of Endocrinology, Key Laboratory of Endocrinology of National Health Commission, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Duan L; Department of Endocrinology, Key Laboratory of Endocrinology of National Health Commission, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Lv X; Department of Endocrinology, Key Laboratory of Endocrinology of National Health Commission, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Wu H; State Key Laboratory of Bioactive Substrate and Function of Natural Medicine, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Tang Y; Department of Pharmacy, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Zhu H; Department of Endocrinology, Key Laboratory of Endocrinology of National Health Commission, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Chen X; State Key Laboratory of Bioactive Substrate and Function of Natural Medicine, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
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Źródło :
Basic & clinical pharmacology & toxicology [Basic Clin Pharmacol Toxicol] 2022 Sep; Vol. 131 (3), pp. 174-188. Date of Electronic Publication: 2022 Jul 01.
Typ publikacji :
Journal Article
MeSH Terms :
Ligands*
Lipogenesis*/drug effects
Lipogenesis*/physiology
Receptors, Somatostatin*/metabolism
Somatostatin*/analogs & derivatives
Somatostatin*/pharmacology
3T3-L1 Cells/drug effects ; 3T3-L1 Cells/metabolism ; Adipocytes/drug effects ; Adipocytes/metabolism ; Animals ; CCAAT-Enhancer-Binding Protein-alpha/genetics ; CCAAT-Enhancer-Binding Protein-alpha/metabolism ; Cell Differentiation ; Cell Proliferation ; Mice ; PPAR gamma/genetics ; PPAR gamma/metabolism ; Phosphatidylinositol 3-Kinases/metabolism ; Proto-Oncogene Proteins c-akt/metabolism
Czasopismo naukowe
Tytuł :
Changes in dorsal root ganglion CGRP expression in mouse pinch nerve injury model: Modulation by Somatostatin type-2 receptor.
Autorzy :
Xiang Q; Institute of Medicine, Medical research center, Jishou University, Hunan, China.
Tao JS; Institute of Medicine, Medical research center, Jishou University, Hunan, China.
Li JJ; Institute of Medicine, Medical research center, Jishou University, Hunan, China.
Tian RB; Institute of Medicine, Medical research center, Jishou University, Hunan, China.
Li XH; Institute of Pharmaceutical Sciences, Jishou University, Hunan, China. Electronic address: lxh_.
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Źródło :
Journal of chemical neuroanatomy [J Chem Neuroanat] 2022 Apr; Vol. 121, pp. 102086. Date of Electronic Publication: 2022 Mar 04.
Typ publikacji :
Journal Article
MeSH Terms :
Ganglia, Spinal*/metabolism
Neuralgia*/metabolism
Receptors, Somatostatin/*metabolism
Animals ; Calcitonin Gene-Related Peptide/metabolism ; Mice ; Rats, Sprague-Dawley ; Somatostatin/metabolism
Czasopismo naukowe
Tytuł :
The Future of Somatostatin Receptor Ligands in Acromegaly.
Autorzy :
Gadelha MR; Endocrine Unit and Neuroendocrinology Research Center, Medical School and Hospital Universitário Clementino Fraga Filho - Universidade Federal do Rio de Janeiro, Rio de Janeiro, 21941-913, Brazil.; Neuroendocrine Unit - Instituto Estadual do Cérebro Paulo Niemeyer, Secretaria Estadual de Saúde, Rio de Janeiro, 20231-092, Brazil.; Neuropathology and Molecular Genetics Laboratory, Instituto Estadual do Cérebro Paulo Niemeyer, Secretaria Estadual de Saúde, Rio de Janeiro, 20231-092, Brazil.
Wildemberg LE; Endocrine Unit and Neuroendocrinology Research Center, Medical School and Hospital Universitário Clementino Fraga Filho - Universidade Federal do Rio de Janeiro, Rio de Janeiro, 21941-913, Brazil.; Neuroendocrine Unit - Instituto Estadual do Cérebro Paulo Niemeyer, Secretaria Estadual de Saúde, Rio de Janeiro, 20231-092, Brazil.
Kasuki L; Endocrine Unit and Neuroendocrinology Research Center, Medical School and Hospital Universitário Clementino Fraga Filho - Universidade Federal do Rio de Janeiro, Rio de Janeiro, 21941-913, Brazil.; Neuroendocrine Unit - Instituto Estadual do Cérebro Paulo Niemeyer, Secretaria Estadual de Saúde, Rio de Janeiro, 20231-092, Brazil.
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Źródło :
The Journal of clinical endocrinology and metabolism [J Clin Endocrinol Metab] 2022 Jan 18; Vol. 107 (2), pp. 297-308.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Acromegaly/*drug therapy
Antineoplastic Agents, Hormonal/*administration & dosage
Growth Hormone-Secreting Pituitary Adenoma/*drug therapy
Receptors, Somatostatin/*metabolism
Acromegaly/blood ; Acromegaly/etiology ; Antineoplastic Agents, Hormonal/adverse effects ; Biomarkers, Tumor/blood ; Growth Hormone-Secreting Pituitary Adenoma/blood ; Growth Hormone-Secreting Pituitary Adenoma/complications ; Growth Hormone-Secreting Pituitary Adenoma/genetics ; Humans ; Octreotide/administration & dosage ; Octreotide/adverse effects ; Peptides, Cyclic/administration & dosage ; Peptides, Cyclic/adverse effects ; Precision Medicine/methods ; Precision Medicine/trends ; Quality of Life ; Randomized Controlled Trials as Topic ; Somatostatin/administration & dosage ; Somatostatin/adverse effects ; Somatostatin/analogs & derivatives ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Knock-in mouse models for studying somatostatin and cholecystokinin expressing cells.
Autorzy :
Balog M; Munroe-Meyer Institute for Genetics and Rehabilitation, University of Nebraska Medical Center Omaha, NE, USA; Department of Medical Biology and Genetics, Faculty of Medicine, University of Osijek, Osijek, Croatia.
Anderson A; Munroe-Meyer Institute for Genetics and Rehabilitation, University of Nebraska Medical Center Omaha, NE, USA.
Gurumurthy CB; Mouse Genome Engineering Core Facility, University of Nebraska Medical Center, Omaha, NE, USA; Department of Pharmacology and Experimental Neuroscience, College of Medicine, University of Nebraska Medical Center, Omaha, NE, USA.
Quadros RM; Mouse Genome Engineering Core Facility, University of Nebraska Medical Center, Omaha, NE, USA.
Korade Z; Department of Pediatrics, University of Nebraska Medical Center Omaha, NE, USA; Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center Omaha, NE, USA; Child Health Research Institute, University of Nebraska Medical Center Omaha, NE, USA. Electronic address: .
Mirnics K; Munroe-Meyer Institute for Genetics and Rehabilitation, University of Nebraska Medical Center Omaha, NE, USA; Department of Pharmacology and Experimental Neuroscience, College of Medicine, University of Nebraska Medical Center, Omaha, NE, USA; Department of Pediatrics, University of Nebraska Medical Center Omaha, NE, USA; Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center Omaha, NE, USA; Child Health Research Institute, University of Nebraska Medical Center Omaha, NE, USA. Electronic address: .
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Źródło :
Journal of neuroscience methods [J Neurosci Methods] 2022 Nov 01; Vol. 381, pp. 109704. Date of Electronic Publication: 2022 Sep 05.
Typ publikacji :
Journal Article
MeSH Terms :
Cholecystokinin*/genetics
Somatostatin*/genetics
Animals ; Codon, Initiator ; Codon, Terminator ; Mice ; Mice, Inbred C57BL ; Mice, Transgenic
Czasopismo naukowe
Tytuł :
Lanreotide as maintenance therapy after first-line treatment in patients with non-resectable duodeno-pancreatic neuroendocrine tumours: An international double-blind, placebo-controlled randomised phase II trial - Prodige 31 REMINET: An FFCD study.
Autorzy :
Lepage C; EPICAD INSERM UMR LNC 1231, University of Burgundy Franche Comté, Dijon, France; Department of HGE & Digestive Oncology, University Hospital Dijon, University of Burgundy, Dijon, France. Electronic address: .
Phelip JM; Department of HGE & Digestive Oncology, University Hospital St Etienne, France.
Lievre A; Department of Gastroenterology, Rennes University Hospital, Rennes 1 University, INSERM U1242 'Chemistry Oncogenesis Stress Signalling', Rennes, FFCD, France.
Le-Malicot K; EPICAD INSERM UMR LNC 1231, University of Burgundy Franche Comté, Dijon, France.
Dahan L; C.H.U. la Timone and Université de la Méditerranée, Marseille, France.
Tougeron D; Department of Hepato-gastroenterology, Poitiers University Hospital and Poitiers University, Poitiers, France.
Toumpanakis C; Centre for Gastroenterology, Neuroendocrine Tumour Unit, ENETS Centre of Excellence, Royal Free Hospital, London, UK.
Di-Fiore F; Normandie University, UNIROUEN, Inserm 1245, IRON Group, Hôpital Universitaire de Rouen, Centre Henri-Becquerel, Département d'oncolgie Médicale, Service d'hépato-gastroentérologie, 76000 Rouen, France.
Lombard-Bohas C; Cancer Institute, ENETS Centre of Excellence, Hospices Civils de Lyon, France.
Borbath I; Department of Gastroenterology, Cliniques Universitaires Saint-Luc, Université Catholique de Louvain, Brussels, Belgium.
Coriat R; AP-HP, Université Paris Descartes, Faculté de Médecine, Hôpital Cochin, Gastroenterology and Endoscopy Unit, Sorbonne Paris Cité, 75014 Paris, France.
Lecomte T; Department of HGE & Digestive Oncology, University Hospital Tours, François-Rabelais University, Tours, France.
Guimbaud R; Centre Hospitalier Universitaire de Toulouse, Toulouse, France.
Petorin C; Digestive Surgery and Oncological Department, Hospital Estaing, Clermont-Ferrand, France.
Legoux JL; Department of Hepato-Gastroenterology, La Source Hospital, Orléans, France.
Michel P; Normandie University, UNIROUEN, Inserm 1245, IRON Group, Hôpital Universitaire de Rouen, Centre Henri-Becquerel, Département d'oncolgie Médicale, Service d'hépato-gastroentérologie, 76000 Rouen, France.
Scoazec JY; Department of Pathology, University Paris-Saclay, Gustave Roussy Cancer Center, Villejuif, France.
Smith D; Hôpital Haut Lévêque, Service d'hépato-gastroentérologie, Pessac, France.
Walter T; Cancer Institute, ENETS Centre of Excellence, Hospices Civils de Lyon, France.
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Źródło :
European journal of cancer (Oxford, England : 1990) [Eur J Cancer] 2022 Nov; Vol. 175, pp. 31-40. Date of Electronic Publication: 2022 Sep 07.
Typ publikacji :
Clinical Trial, Phase II; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
MeSH Terms :
Neuroendocrine Tumors*/pathology
Pancreatic Neoplasms*/drug therapy
Pancreatic Neoplasms*/pathology
Peptides, Cyclic*/therapeutic use
Somatostatin*/analogs & derivatives
Somatostatin*/therapeutic use
Humans
Czasopismo naukowe
Tytuł :
Pituitary acting drugs: cabergoline and pasireotide.
Autorzy :
Gadelha MR; Neuroendocrinology Research Center/Endocrinology Division, Medical School and Hospital Universitário Clementino Fraga Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil. .; Neuropathology and Molecular Genetics Laboratory, Instituto Estadual do Cérebro Paulo Niemeyer, Rio de Janeiro, Brazil. .; Neuroendocrinology Division, Instituto Estadual do Cérebro Paulo Niemeyer, Rio de Janeiro, Brazil. .; Rua Prof. Rodolpho Paulo Rocco, 255, 9th floor, Ilha do Fundão, 21941-913, Rio de Janeiro, Brazil. .
Wildemberg LE; Neuroendocrinology Research Center/Endocrinology Division, Medical School and Hospital Universitário Clementino Fraga Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.; Neuroendocrinology Division, Instituto Estadual do Cérebro Paulo Niemeyer, Rio de Janeiro, Brazil.
Shimon I; Institute of Endocrinology, Petach Tikva, and Sackler School of Medicine, Beilinson Hospital, Tel-Aviv University, Tel-Aviv, Israel.
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Źródło :
Pituitary [Pituitary] 2022 Oct; Vol. 25 (5), pp. 722-725. Date of Electronic Publication: 2022 Jun 07.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Cabergoline*/therapeutic use
Pituitary ACTH Hypersecretion*/drug therapy
Pituitary ACTH Hypersecretion*/pathology
Somatostatin*/therapeutic use
Humans ; Pituitary Gland/pathology
Czasopismo naukowe
Tytuł :
Somatostatin receptor-directed molecular imaging for therapeutic decision-making in patients with medullary thyroid carcinoma.
Autorzy :
Serfling SE; Department of Nuclear Medicine, University Hospital Würzburg, Würzburg, Germany. serfling_.
Zhi Y; Department of Otorhinolaryngology, Plastic, Aesthetic and Reconstructive Head and Neck Surgery, University Hospital Würzburg, Würzburg, Germany.
Megerle F; Division of Endocrinology and Diabetes, Department of Medicine I, University Hospital Würzburg, Würzburg, Germany.
Fassnacht M; Division of Endocrinology and Diabetes, Department of Medicine I, University Hospital Würzburg, Würzburg, Germany.
Buck AK; Department of Nuclear Medicine, University Hospital Würzburg, Würzburg, Germany.
Lapa C; Nuclear Medicine, Faculty of Medicine, University of Augsburg, Augsburg, Germany.
Werner RA; Department of Nuclear Medicine, University Hospital Würzburg, Würzburg, Germany. werner_.; Johns Hopkins School of Medicine, The Russell H Morgan Department of Radiology and Radiological Science, Division of Nuclear Medicine, Baltimore, MD, USA. werner_.
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Źródło :
Endocrine [Endocrine] 2022 Oct; Vol. 78 (1), pp. 169-176. Date of Electronic Publication: 2022 Jun 25.
Typ publikacji :
Journal Article
MeSH Terms :
Receptors, Somatostatin*
Thyroid Neoplasms*/diagnostic imaging
Thyroid Neoplasms*/pathology
Thyroid Neoplasms*/therapy
Carcinoma, Neuroendocrine ; Humans ; Molecular Imaging ; Positron Emission Tomography Computed Tomography
SCR Disease Name :
Thyroid cancer, medullary
Czasopismo naukowe
Tytuł :
Molecular and cellular evolution of the primate dorsolateral prefrontal cortex.
Autorzy :
Ma S; Department of Neuroscience, Yale School of Medicine, New Haven, CT 06510, USA.
Skarica M; Department of Neuroscience, Yale School of Medicine, New Haven, CT 06510, USA.
Li Q; Department of Neuroscience, Yale School of Medicine, New Haven, CT 06510, USA.
Xu C; Department of Neuroscience, Yale School of Medicine, New Haven, CT 06510, USA.
Risgaard RD; Waisman Center, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI 53705, USA.; Medical Scientist Training Program, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI 53705, USA.
Tebbenkamp ATN; Department of Neuroscience, Yale School of Medicine, New Haven, CT 06510, USA.
Mato-Blanco X; Neurogenomics Group, Research Programme on Biomedical Informatics (GRIB), Hospital del Mar Medical Research Institute (IMIM), MELIS, Universitat Pompeu Fabra, 08003 Barcelona, Catalonia, Spain.
Kovner R; Department of Neuroscience, Yale School of Medicine, New Haven, CT 06510, USA.
Krsnik Ž; Department of Neuroscience, Yale School of Medicine, New Haven, CT 06510, USA.; Croatian Institute for Brain Research, School of Medicine, University of Zagreb, 10000 Zagreb, Croatia.
de Martin X; Neurogenomics Group, Research Programme on Biomedical Informatics (GRIB), Hospital del Mar Medical Research Institute (IMIM), MELIS, Universitat Pompeu Fabra, 08003 Barcelona, Catalonia, Spain.
Luria V; Department of Neuroscience, Yale School of Medicine, New Haven, CT 06510, USA.
Martí-Pérez X; Neurogenomics Group, Research Programme on Biomedical Informatics (GRIB), Hospital del Mar Medical Research Institute (IMIM), MELIS, Universitat Pompeu Fabra, 08003 Barcelona, Catalonia, Spain.
Liang D; Department of Neuroscience, Yale School of Medicine, New Haven, CT 06510, USA.
Karger A; IT-Research Computing, Harvard Medical School, Boston, MA, USA.
Schmidt DK; Waisman Center, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI 53705, USA.
Gomez-Sanchez Z; Waisman Center, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI 53705, USA.
Qi C; Department of Neuroscience, Yale School of Medicine, New Haven, CT 06510, USA.
Gobeske KT; Division of Neurocritical Care and Emergency Neurology, Department of Neurology, Yale School of Medicine, New Haven, CT 06510, USA.
Pochareddy S; Department of Neuroscience, Yale School of Medicine, New Haven, CT 06510, USA.
Debnath A; Waisman Center, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI 53705, USA.
Hottman CJ; Waisman Center, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI 53705, USA.
Spurrier J; Program in Cellular Neuroscience, Neurodegeneration and Repair, Department of Neurology, Yale School of Medicine, New Haven, CT 06536, USA.
Teo L; Australian Regenerative Medicine Institute, 15 Innovation Walk, Monash University, Clayton, VIC 3800, Australia.
Boghdadi AG; Australian Regenerative Medicine Institute, 15 Innovation Walk, Monash University, Clayton, VIC 3800, Australia.
Homman-Ludiye J; Australian Regenerative Medicine Institute, 15 Innovation Walk, Monash University, Clayton, VIC 3800, Australia.
Ely JJ; MAEBIOS, Alamogordo, NM 88310, USA.; Department of Anthropology and Center for the Advanced Study of Human Paleobiology, The George Washington University, Washington, DC, USA.
Daadi EW; Southwest National Primate Research Center, Texas Biomedical Research Institute, San Antonio, TX, USA.
Mi D; Tsinghua-Peking Center for Life Sciences, IDG/McGovern Institute for Brain Research, School of Life Sciences, Tsinghua University, Beijing 100084, China.
Daadi M; Southwest National Primate Research Center, Texas Biomedical Research Institute, San Antonio, TX, USA.; Department of Cell Systems and Anatomy, Radiology, Long School of Medicine, UT Health, San Antonio, TX, USA.; NeoNeuron LLC, Palo Alto, CA 94306, USA.
Marín O; Centre for Developmental Neurobiology, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London SE1 1UL, UK.; MRC Centre for Neurodevelopmental Disorders, King's College London, London SE1 1UL, UK.
Hof PR; Nash Family Department of Neuroscience and Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Rasin MR; Department of Neuroscience and Cell Biology, Robert Wood Johnson Medical School, Rutgers University, Piscataway, NJ 08854, USA.
Bourne J; Australian Regenerative Medicine Institute, 15 Innovation Walk, Monash University, Clayton, VIC 3800, Australia.
Sherwood CC; Department of Anthropology and Center for the Advanced Study of Human Paleobiology, The George Washington University, Washington, DC, USA.
Santpere G; Department of Neuroscience, Yale School of Medicine, New Haven, CT 06510, USA.; Neurogenomics Group, Research Programme on Biomedical Informatics (GRIB), Hospital del Mar Medical Research Institute (IMIM), MELIS, Universitat Pompeu Fabra, 08003 Barcelona, Catalonia, Spain.
Girgenti MJ; Department of Psychiatry, Yale School of Medicine, New Haven, CT 06510, USA.; National Center for PTSD, US Department of Veterans Affairs, White River Junction, VT, USA.
Strittmatter SM; Department of Neuroscience, Yale School of Medicine, New Haven, CT 06510, USA.; Program in Cellular Neuroscience, Neurodegeneration and Repair, Department of Neurology, Yale School of Medicine, New Haven, CT 06536, USA.; Kavli Institute for Neuroscience, Yale School of Medicine, New Haven, CT 06510, USA.
Sousa AMM; Waisman Center, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI 53705, USA.; Department of Neuroscience, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI 53705, USA.
Sestan N; Department of Neuroscience, Yale School of Medicine, New Haven, CT 06510, USA.; Department of Psychiatry, Yale School of Medicine, New Haven, CT 06510, USA.; Kavli Institute for Neuroscience, Yale School of Medicine, New Haven, CT 06510, USA.; Departments of Genetics and Comparative Medicine, Program in Cellular Neuroscience, Neurodegeneration and Repair, and Yale Child Study Center, Yale School of Medicine, New Haven, CT 06510, USA.
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Źródło :
Science (New York, N.Y.) [Science] 2022 Sep 30; Vol. 377 (6614), pp. eabo7257. Date of Electronic Publication: 2022 Sep 30.
Typ publikacji :
Journal Article
MeSH Terms :
Dorsolateral Prefrontal Cortex*/cytology
Dorsolateral Prefrontal Cortex*/metabolism
Evolution, Molecular*
Primates*/genetics
Somatostatin*/genetics
Somatostatin*/metabolism
Tyrosine 3-Monooxygenase*/genetics
Tyrosine 3-Monooxygenase*/metabolism
Adult ; Animals ; Dopamine/metabolism ; Humans ; Pan troglodytes ; Single-Cell Analysis ; Transcriptome
Czasopismo naukowe
Tytuł :
The spatial scale of somatostatin subnetworks increases from sensory to association cortex.
Autorzy :
Khoury CF; Center for the Neural Basis of Cognition, Pittsburgh, PA 15213, USA; Department of Neuroscience, University of Pittsburgh, Pittsburgh, PA 15260, USA.
Fala NG; Department of Neuroscience, University of Pittsburgh, Pittsburgh, PA 15260, USA.
Runyan CA; Center for the Neural Basis of Cognition, Pittsburgh, PA 15213, USA; Department of Neuroscience, University of Pittsburgh, Pittsburgh, PA 15260, USA. Electronic address: .
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Źródło :
Cell reports [Cell Rep] 2022 Sep 06; Vol. 40 (10), pp. 111319.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Auditory Cortex*/physiology
Somatostatin*/metabolism
Animals ; Interneurons/metabolism ; Mice ; Neurons/metabolism
Czasopismo naukowe

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