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Wyszukujesz frazę ""pharmacokinetics"" wg kryterium: Temat


Tytuł :
Nonparametric Methods in Population Pharmacokinetics.
Autorzy :
Goutelle S; Hospices Civils de Lyon, Groupement Hospitalier Nord, Service de Pharmacie, Lyon, France.; CNRS, UMR 5558, Laboratoire de Biométrie et Biologie Évolutive, Villeurbanne, France.; Univ Lyon, Université Claude Bernard Lyon 1, Lyon, France.
Woillard JB; Univ. Limoges, Limoges, France.; INSERM, IPPRITT, Limoges, France.; CHU Limoges, Department of Pharmacology and Toxicology, Limoges, France.
Neely M; Keck School of Medicine, University of Southern California, Los Angeles, California, USA.; Laboratory of Applied Pharmacokinetics and Bioinformatics at the Saban Research Institute, Children's Hospital Los Angeles, Los Angeles, California, USA.
Yamada W; Keck School of Medicine, University of Southern California, Los Angeles, California, USA.
Bourguignon L; Hospices Civils de Lyon, Groupement Hospitalier Nord, Service de Pharmacie, Lyon, France.; CNRS, UMR 5558, Laboratoire de Biométrie et Biologie Évolutive, Villeurbanne, France.; Univ Lyon, Université Claude Bernard Lyon 1, Lyon, France.
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Źródło :
Journal of clinical pharmacology [J Clin Pharmacol] 2022 Feb; Vol. 62 (2), pp. 142-157. Date of Electronic Publication: 2020 Oct 26.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Algorithms*
Models, Biological*
Models, Statistical*
Pharmacokinetics*
Software Design*
Age Factors ; Alkynes/pharmacokinetics ; Area Under Curve ; Benzoxazines/pharmacokinetics ; Cyclopropanes/pharmacokinetics ; Humans ; Metabolic Clearance Rate ; Sex Factors
Czasopismo naukowe
Tytuł :
Parametric Approaches in Population Pharmacokinetics.
Autorzy :
Guidi M; Center for Research and Innovation in Clinical Pharmaceutical Sciences, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.; Service of Clinical Pharmacology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.
Csajka C; Center for Research and Innovation in Clinical Pharmaceutical Sciences, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.; Institute of Pharmaceutical Sciences of Western Switzerland, University of Geneva, University of Lausanne, Geneva, Lausanne, Switzerland.
Buclin T; Service of Clinical Pharmacology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.
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Źródło :
Journal of clinical pharmacology [J Clin Pharmacol] 2022 Feb; Vol. 62 (2), pp. 125-141. Date of Electronic Publication: 2020 Oct 26.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Algorithms*
Models, Biological*
Models, Statistical*
Pharmacokinetics*
Software Design*
Age Factors ; Alkynes/pharmacokinetics ; Area Under Curve ; Benzoxazines/pharmacokinetics ; Cyclopropanes/pharmacokinetics ; Humans ; Metabolic Clearance Rate ; Sex Factors
Czasopismo naukowe
Tytuł :
Statistical optimization of bile salt deployed nanovesicles as a potential platform for oral delivery of piperine: accentuated antiviral and anti-inflammatory activity in MERS-CoV challenged mice.
Autorzy :
Zakaria MY; Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Port Said University, Port Said, Egypt.
Fayad E; Department of Biotechnology, Faculty of Sciences, Taif University, Taif, Saudi Arabia.
Althobaiti F; Department of Biotechnology, Faculty of Sciences, Taif University, Taif, Saudi Arabia.
Zaki I; Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Port Said University, Port Said, Egypt.
Abu Almaaty AH; Department of Zoology, Faculty of Science, Port Said University, Port Said, Egypt.
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Źródło :
Drug delivery [Drug Deliv] 2021 Dec; Vol. 28 (1), pp. 1150-1165.
Typ publikacji :
Journal Article
MeSH Terms :
Alkaloids*/administration & dosage
Alkaloids*/pharmacokinetics
Benzodioxoles*/administration & dosage
Benzodioxoles*/pharmacokinetics
Piperidines*/administration & dosage
Piperidines*/pharmacokinetics
Polyunsaturated Alkamides*/administration & dosage
Polyunsaturated Alkamides*/pharmacokinetics
Bile Acids and Salts/*pharmacokinetics
Drug Delivery Systems/*methods
Middle East Respiratory Syndrome Coronavirus/*drug effects
Administration, Oral ; Animals ; Antiviral Agents/administration & dosage ; Antiviral Agents/pharmacokinetics ; Biological Availability ; Cytochrome P-450 Enzyme Inhibitors/administration & dosage ; Cytochrome P-450 Enzyme Inhibitors/pharmacokinetics ; Drug Liberation ; Liposomes ; Mice ; Molecular Docking Simulation ; Nanostructures ; Plants, Medicinal ; Surface-Active Agents/pharmacokinetics
Czasopismo naukowe
Tytuł :
Impact of cumulative fluid balance on the pharmacokinetics of extended infusion meropenem in critically ill patients with sepsis.
Autorzy :
Pařízková RČ; Department of Anesthesiology, Resuscitation and Intensive Medicine, Charles University, Faculty of Medicine in Hradec Králové and University Hospital Hradec Králové, Sokolská 581, 50005, Hradec Králové, Czech Republic.
Martínková J; Department of Surgery, University Hospital Hradec Králové, Sokolská 581, 50005, Hradec Králové, Czech Republic.
Havel E; Department of Surgery, Charles University, Faculty of Medicine in Hradec Králové and University Hospital Hradec Králové, Sokolská 581, 50005, Hradec Králové, Czech Republic.
Šafránek P; Department of Surgery, Charles University, Faculty of Medicine in Hradec Králové and University Hospital Hradec Králové, Sokolská 581, 50005, Hradec Králové, Czech Republic.
Kaška M; Department of Surgery, Charles University, Faculty of Medicine in Hradec Králové and University Hospital Hradec Králové, Sokolská 581, 50005, Hradec Králové, Czech Republic.
Astapenko D; Department of Anesthesiology, Resuscitation and Intensive Medicine, Charles University, Faculty of Medicine in Hradec Králové and University Hospital Hradec Králové, Sokolská 581, 50005, Hradec Králové, Czech Republic.
Bezouška J; Department of Surgery, University Hospital Hradec Králové, Sokolská 581, 50005, Hradec Králové, Czech Republic.
Chládek J; Department of Pharmacology, Charles University, Faculty of Medicine in Hradec Králové, Šimkova 870, 50003, Hradec Králové, Czech Republic. .
Černý V; Department of Anesthesiology, Resuscitation and Intensive Medicine, Charles University, Faculty of Medicine in Hradec Králové and University Hospital Hradec Králové, Sokolská 581, 50005, Hradec Králové, Czech Republic.
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Źródło :
Critical care (London, England) [Crit Care] 2021 Jul 17; Vol. 25 (1), pp. 251. Date of Electronic Publication: 2021 Jul 17.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Pharmacokinetics*
Meropenem/*pharmacokinetics
Sepsis/*drug therapy
Water-Electrolyte Balance/*drug effects
APACHE ; Adult ; Aged ; Aged, 80 and over ; Anti-Bacterial Agents/metabolism ; Anti-Bacterial Agents/pharmacokinetics ; Bayes Theorem ; Critical Illness/therapy ; Czech Republic ; Female ; Humans ; Intensive Care Units/organization & administration ; Intensive Care Units/statistics & numerical data ; Male ; Meropenem/metabolism ; Middle Aged ; Prospective Studies ; Sepsis/physiopathology
Czasopismo naukowe
Tytuł :
Predicting a therapeutic cut-off serum level of itraconazole in recalcitrant tinea corporis and cruris-A prospective trial.
Autorzy :
Khurana A; Department of Dermatology, Dr Ram Manohar Lohia Hospital and Atal Bihari Vajpayee Institute of Medical Sciences, New Delhi, India.
Agarwal A; Department of Dermatology, Dr Ram Manohar Lohia Hospital and Atal Bihari Vajpayee Institute of Medical Sciences, New Delhi, India.
Singh A; Medical Mycology Unit, Department of Microbiology, Vallabhbhai Patel Chest Institute, University of Delhi, New Delhi, India.
Sardana K; Department of Dermatology, Dr Ram Manohar Lohia Hospital and Atal Bihari Vajpayee Institute of Medical Sciences, New Delhi, India.
Ghadlinge M; Department of Pharmacology, Dr Ram Manohar Lohia Hospital and Atal Bihari Vajpayee Institute of Medical Sciences, New Delhi, India.
Agrawal D; Department of Dermatology, Dr Ram Manohar Lohia Hospital and Atal Bihari Vajpayee Institute of Medical Sciences, New Delhi, India.
Panesar S; Department of Community Medicine, Dr Ram Manohar Lohia Hospital and Atal Bihari Vajpayee Institute of Medical Sciences, New Delhi, India.
Sethia K; Department of Dermatology, Dr Ram Manohar Lohia Hospital and Atal Bihari Vajpayee Institute of Medical Sciences, New Delhi, India.
Chowdhary A; Medical Mycology Unit, Department of Microbiology, Vallabhbhai Patel Chest Institute, University of Delhi, New Delhi, India.
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Źródło :
Mycoses [Mycoses] 2021 Dec; Vol. 64 (12), pp. 1480-1488. Date of Electronic Publication: 2021 Oct 09.
Typ publikacji :
Journal Article; Randomized Controlled Trial
MeSH Terms :
Antifungal Agents*/pharmacokinetics
Antifungal Agents*/therapeutic use
Tinea*/drug therapy
Itraconazole/*pharmacokinetics
Humans ; Itraconazole/therapeutic use ; Prospective Studies ; Terbinafine/pharmacokinetics
Czasopismo naukowe
Tytuł :
Pharmacokinetic/Pharmacodynamic Simulations of Cost-Effective Dosage Regimens of Ceftolozane-Tazobactam and Ceftazidime-Avibactam in Patients with Renal Impairment.
Autorzy :
Dheyriat L; Hospices Civils de Lyongrid.413852.9, Groupement Hospitalier Nord, Service de Pharmacie, Lyon, France.
Bourguignon L; Hospices Civils de Lyongrid.413852.9, Groupement Hospitalier Nord, Service de Pharmacie, Lyon, France.; Université Lyon, UMR CNRS 5558, Laboratoire de Biométrie et Biologie Evolutive, Villeurbanne, France.; Université Lyon, Faculté de Médecine et de Pharmacie de Lyon, Lyon, France.
Perpoint T; Hospices Civils de Lyongrid.413852.9, Groupement Hospitalier Nord, Service des Maladies Infectieuses et Tropicales, Lyon, France.
Ferry T; Université Lyon, Faculté de Médecine et de Pharmacie de Lyon, Lyon, France.; Hospices Civils de Lyongrid.413852.9, Groupement Hospitalier Nord, Service des Maladies Infectieuses et Tropicales, Lyon, France.; CIRI - Centre International de Recherche en Infectiologie, INSERM U1111, CNRS UMR 5308, ENS Lyon, Université Claude Bernard Lyon 1, Lyon, France.
Goutelle S; Hospices Civils de Lyongrid.413852.9, Groupement Hospitalier Nord, Service de Pharmacie, Lyon, France.; Université Lyon, UMR CNRS 5558, Laboratoire de Biométrie et Biologie Evolutive, Villeurbanne, France.; Université Lyon, Faculté de Médecine et de Pharmacie de Lyon, Lyon, France.
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Źródło :
Antimicrobial agents and chemotherapy [Antimicrob Agents Chemother] 2022 Mar 15; Vol. 66 (3), pp. e0210421. Date of Electronic Publication: 2022 Jan 18.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Ceftazidime*/pharmacokinetics
Ceftazidime*/therapeutic use
Cephalosporins*/pharmacokinetics
Anti-Bacterial Agents/pharmacology ; Azabicyclo Compounds/pharmacokinetics ; Azabicyclo Compounds/therapeutic use ; Cost-Benefit Analysis ; Drug Combinations ; Humans ; Microbial Sensitivity Tests ; Tazobactam/pharmacokinetics ; Tazobactam/therapeutic use
Czasopismo naukowe
Tytuł :
A quantitative model for metabolic intervention using gut microbes.
Autorzy :
Mays ZJS; Department of Chemical & Biological Engineering, Tufts University, Medford, Massachusetts, USA.
Nair NU; Department of Chemical & Biological Engineering, Tufts University, Medford, Massachusetts, USA.
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Źródło :
Biotechnology progress [Biotechnol Prog] 2021 Sep; Vol. 37 (5), pp. e3125. Date of Electronic Publication: 2021 Jan 16.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Drug Delivery Systems*
Models, Biological*
Probiotics*/metabolism
Probiotics*/pharmacokinetics
Gastrointestinal Microbiome/*physiology
Administration, Oral ; Adolescent ; Adult ; Child ; Child, Preschool ; Humans ; Infant ; Infant, Newborn ; Intestinal Absorption/physiology ; Pharmacokinetics ; Phenylketonurias/therapy ; Young Adult
Czasopismo naukowe
Tytuł :
Population Pharmacokinetics Analysis of Pemigatinib in Patients With Advanced Malignancies.
Autorzy :
Ji T; Incyte Research Institute, Wilmington, Delaware, USA.
Chen X; Incyte Research Institute, Wilmington, Delaware, USA.
Liu X; Incyte Research Institute, Wilmington, Delaware, USA.
Yeleswaram S; Incyte Research Institute, Wilmington, Delaware, USA.
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Źródło :
Clinical pharmacology in drug development [Clin Pharmacol Drug Dev] 2022 Apr; Vol. 11 (4), pp. 454-466. Date of Electronic Publication: 2022 Jan 29.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Neoplasms*/drug therapy
Neoplasms*/pathology
Pyrimidines*/pharmacokinetics
Clinical Trials, Phase I as Topic ; Female ; Humans ; Male ; Morpholines/pharmacokinetics ; Pyrroles/pharmacokinetics
Czasopismo naukowe
Tytuł :
Population Pharmacokinetics of Ponatinib in Healthy Adult Volunteers and Patients With Hematologic Malignancies and Model-Informed Dose Selection for Pediatric Development.
Autorzy :
Hanley MJ; Millennium Pharmaceuticals, Inc., a wholly owned subsidiary of Takeda Pharmaceutical Company Limited, Cambridge, Massachusetts, USA.
Diderichsen PM; Certara, Princeton, New Jersey, USA.
Narasimhan N; Millennium Pharmaceuticals, Inc., a wholly owned subsidiary of Takeda Pharmaceutical Company Limited, Cambridge, Massachusetts, USA.
Srivastava S; Millennium Pharmaceuticals, Inc., a wholly owned subsidiary of Takeda Pharmaceutical Company Limited, Cambridge, Massachusetts, USA.
Gupta N; Millennium Pharmaceuticals, Inc., a wholly owned subsidiary of Takeda Pharmaceutical Company Limited, Cambridge, Massachusetts, USA.
Venkatakrishnan K; Millennium Pharmaceuticals, Inc., a wholly owned subsidiary of Takeda Pharmaceutical Company Limited, Cambridge, Massachusetts, USA.
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Źródło :
Journal of clinical pharmacology [J Clin Pharmacol] 2022 Apr; Vol. 62 (4), pp. 555-567. Date of Electronic Publication: 2021 Dec 16.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Hematologic Neoplasms*/drug therapy
Pyridazines*/pharmacokinetics
Pyridazines*/therapeutic use
Adult ; Aged ; Aged, 80 and over ; Antineoplastic Agents/pharmacokinetics ; Antineoplastic Agents/therapeutic use ; Body Weight ; Clinical Trials as Topic ; Female ; Fusion Proteins, bcr-abl/genetics ; Healthy Volunteers ; Humans ; Imidazoles ; Male ; Middle Aged ; Pediatrics ; Protein Kinase Inhibitors/pharmacokinetics ; Protein Kinase Inhibitors/therapeutic use ; Young Adult
Czasopismo naukowe
Tytuł :
Just say no to postmortem drug dose calculations.
Autorzy :
Maskell PD; Forensic Medicine and Science, University of Glasgow, Glasgow, UK.
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Źródło :
Journal of forensic sciences [J Forensic Sci] 2021 Sep; Vol. 66 (5), pp. 1862-1870. Date of Electronic Publication: 2021 Jul 24.
Typ publikacji :
Journal Article
MeSH Terms :
Drug Dosage Calculations*
Forensic Toxicology*
Pharmacokinetics*
Postmortem Changes*
Amitriptyline/blood ; Amitriptyline/pharmacokinetics ; Humans
Czasopismo naukowe
Tytuł :
A Pharmacokinetic Analysis of Tobramycin in Patients Less than Five Years of Age with Cystic Fibrosis: Assessment of Target Attainment with Extended-Interval Dosing through Simulation.
Autorzy :
Downes KJ; Division of Infectious, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.; Center for Clinical Pharmacology, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.; Center for Pediatric Clinical Effectiveness, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.; Department of Pediatrics, The University of Pennsylvania, Perelman School of Medicine, Philadelphia, Pennsylvania, USA.
Grim A; Department of Pharmacy, Texas Children's Hospital, Houston, Texas, USA.
Shanley L; Clinical Pharmacy, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
Rubenstein RC; Division of Allergy and Pulmonary Medicine, Department of Pediatrics, Washington University School of Medicine, St. Louis, Missouri, USA.
Zuppa AF; Center for Clinical Pharmacology, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.; Division of Critical Care Medicine, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.; Department of Anesthesiology and Critical Care, The University of Pennsylvania, Perelman School of Medicine, Philadelphia, Pennsylvania, USA.
Gastonguay MR; Metrum Research Group, Tariffville, Connecticut, USA.
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Źródło :
Antimicrobial agents and chemotherapy [Antimicrob Agents Chemother] 2022 May 17; Vol. 66 (5), pp. e0237721. Date of Electronic Publication: 2022 Apr 28.
Typ publikacji :
Journal Article
MeSH Terms :
Cystic Fibrosis*/drug therapy
Tobramycin*/pharmacokinetics
Adolescent ; Adult ; Anti-Bacterial Agents/pharmacokinetics ; Child ; Computer Simulation ; Humans ; Retrospective Studies
Czasopismo naukowe
Tytuł :
Implementation of a Vancomycin Dose-Optimization Protocol in Neonates: Impact on Vancomycin Exposure, Biological Parameters, and Clinical Outcomes.
Autorzy :
Gomez L; Laboratory of Pharmacology, Pharmacogenetics, and Toxicology, Grenoble Alpes University Hospital, La Tronche, France.
Boegler D; Neonatal Intensive Care Unit, Grenoble Alpes University Hospital, La Tronche, France.
Epiard C; Neonatal Intensive Care Unit, Grenoble Alpes University Hospital, La Tronche, France.
Alin L; Neonatal Intensive Care Unit, Grenoble Alpes University Hospital, La Tronche, France.
Arata-Bardet J; Pediatric Infectiology, Pediatrics Department, Grenoble Alpes University Hospital, La Tronche, France.
Caspar Y; Laboratory of Bacteriology, Grenoble Alpes University Hospital, La Tronche, France.; University of Grenoble Alpes, CEA, CNRS, IBS, Grenoble, France.
Debillon T; Neonatal Intensive Care Unit, Grenoble Alpes University Hospital, La Tronche, France.; University of Grenoble Alpes, TIMC, MESP Team, La Tronche, France.
Stanke-Labesque F; Laboratory of Pharmacology, Pharmacogenetics, and Toxicology, Grenoble Alpes University Hospital, La Tronche, France.; INSERM 1300, CHU Grenoble Alpes, University of Grenoble Alpes, Grenoble, France.
Gautier-Veyret E; Laboratory of Pharmacology, Pharmacogenetics, and Toxicology, Grenoble Alpes University Hospital, La Tronche, France.; INSERM 1300, CHU Grenoble Alpes, University of Grenoble Alpes, Grenoble, France.
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Źródło :
Antimicrobial agents and chemotherapy [Antimicrob Agents Chemother] 2022 May 17; Vol. 66 (5), pp. e0219121. Date of Electronic Publication: 2022 Apr 25.
Typ publikacji :
Journal Article
MeSH Terms :
Drug-Related Side Effects and Adverse Reactions*/drug therapy
Vancomycin*/pharmacokinetics
Anti-Bacterial Agents/pharmacokinetics ; Drug Monitoring/methods ; Humans ; Infant, Newborn ; Retrospective Studies
Czasopismo naukowe
Tytuł :
Pharmacokinetics of Daprodustat and Metabolites in Individuals with Normal and Impaired Hepatic Function.
Autorzy :
Mahar KM; Clinical Pharmacology Modeling & Simulation, GlaxoSmithKline, Collegeville, Pennsylvania, USA.
Shaddinger BC; Medicine Delivery Unit, GlaxoSmithKline, Collegeville, Pennsylvania, USA.
Ramanjineyulu B; Biostatistics, GlaxoSmithKline, Bangalore, India.
Andrews S; Clinical Science & Study Operations, GlaxoSmithKline, Collegeville, Pennsylvania, USA.
Caltabiano S; Medicine Delivery Unit, GlaxoSmithKline, Collegeville, Pennsylvania, USA.
Lindsay AC; Medicine Delivery Unit, GlaxoSmithKline, Collegeville, Pennsylvania, USA.
Cobitz AR; Medicine Delivery Unit, GlaxoSmithKline, Collegeville, Pennsylvania, USA.
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Źródło :
Clinical pharmacology in drug development [Clin Pharmacol Drug Dev] 2022 May; Vol. 11 (5), pp. 562-575. Date of Electronic Publication: 2022 Mar 30.
Typ publikacji :
Clinical Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Liver Diseases*/metabolism
Prolyl-Hydroxylase Inhibitors*/adverse effects
Prolyl-Hydroxylase Inhibitors*/pharmacokinetics
Barbiturates ; Female ; Glycine/adverse effects ; Glycine/analogs & derivatives ; Glycine/pharmacokinetics ; Humans ; Male
Czasopismo naukowe
Tytuł :
Effects of Hepatic Impairment on the Pharmacokinetic Profile and Safety of Lobeglitazone.
Autorzy :
Park J; Department of Pharmaceutical Medicine and Regulatory Science, Colleges of Medicine and Pharmacy, Yonsei University, Incheon, Republic of Korea.
Kim CO; Department of Clinical Pharmacology, Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea.
Oh ES; Department of Pharmaceutical Medicine and Regulatory Science, Colleges of Medicine and Pharmacy, Yonsei University, Incheon, Republic of Korea.
Lee JI; Department of Internal Medicine, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea.
Kim JK; Department of Internal Medicine, Yongin Severance Hospital, Yonsei University College of Medicine, Gyeonggi-do, Republic of Korea.
Ahn SH; Department of Internal Medicine, Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea.
Kim DY; Department of Internal Medicine, Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea.
Kim SU; Yonsei Liver Centre, Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea.
Kim BK; Yonsei Liver Centre, Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea.
Chung YE; Department of Radiology, Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea.
Kim SM; Department of Nonclinical Development, Chong Kun Dang Research Institute, Chong Kun Dang Pharmaceutical Corp., Ltd, Seoul, Republic of Korea.
Park MS; Department of Pharmaceutical Medicine and Regulatory Science, Colleges of Medicine and Pharmacy, Yonsei University, Incheon, Republic of Korea.; Department of Clinical Pharmacology, Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea.; Department of Pediatrics, Yonsei University College of Medicine, Seoul, Republic of Korea.
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Źródło :
Clinical pharmacology in drug development [Clin Pharmacol Drug Dev] 2022 May; Vol. 11 (5), pp. 576-584. Date of Electronic Publication: 2022 Mar 07.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Liver Diseases*
Thiazolidinediones*/pharmacokinetics
Humans ; Hypoglycemic Agents/pharmacokinetics ; Pyrimidines/adverse effects
Czasopismo naukowe
Tytuł :
The disposition of trimethoprim and sulfadiazine in neonatal foals after intravenous administration.
Autorzy :
Ekstrand C; Department of Biomedical Sciences and Veterinary Public Health, Division of Pharmacology and Toxicology, Swedish University of Agricultural Sciences, Uppsala, Sweden.
Nostell K; Department of Clinical Sciences, Swedish University of Agricultural Sciences, Uppsala, Sweden.
Gehring R; Department of Biomedical Sciences and Veterinary Public Health, Division of Pharmacology and Toxicology, Swedish University of Agricultural Sciences, Uppsala, Sweden.; Department of Population Health Sciences, Division of Veterinary and Comparative Pharmacology, Utrecht University, Utrecht, The Netherlands.
Bondesson U; Department of Chemistry, Environment and Feed Hygiene, National Veterinary Institute (SVA), Uppsala, Sweden.
Bröjer J; Department of Clinical Sciences, Swedish University of Agricultural Sciences, Uppsala, Sweden.
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Źródło :
Veterinary medicine and science [Vet Med Sci] 2022 May; Vol. 8 (3), pp. 1065-1071. Date of Electronic Publication: 2022 Feb 13.
Typ publikacji :
Journal Article
MeSH Terms :
Anti-Infective Agents*/pharmacokinetics
Anti-Infective Agents*/therapeutic use
Trimethoprim*/therapeutic use
Administration, Intravenous/veterinary ; Animals ; Anti-Bacterial Agents ; Escherichia coli ; Gram-Negative Bacteria ; Gram-Positive Bacteria ; Horses ; Sulfadiazine/pharmacokinetics
Czasopismo naukowe
Tytuł :
The science of resveratrol, formulation, pharmacokinetic barriers and its chemotherapeutic potential.
Autorzy :
Robertson I; School of Pharmacy, University of Nottingham, University Park, Nottingham NG7 2RD, UK.
Wai Hau T; School of Pharmacy, University of Nottingham Malaysia, Jalan Broga, 43500 Semenyih, Selangor, Malaysia.
Sami F; Department of Pharmaceutics, Hygia Institute of Pharmaceutical Sciences and Research, Lucknow, India.
Sajid Ali M; Department of Pharmaceutics, College of Pharmacy , Jazan University, Jazan, KSA.
Badgujar V; Gangamai College of Pharmacy, Nagaon, Dhule, India.
Murtuja S; Department of Pharmaceutical Sciences and Technology, Birla Institute of Technology, Mesra, Ranchi, Jharkhand 835215, India; KIET School of Pharmacy, KIET Group of Institutions, Ghaziabad 201206, Uttar Pradesh, India.
Saquib Hasnain M; Palamu Institute of Pharmacy, Chianki, Jharkhand 822102, India.
Khan A; Department of Pharmacy, KPJ University College, Lot PT 17010, Persiaran Seriemas Utama, Kota Seriemas, 71800 Nilai, Negeri Sembilan, Malaysia.
Majeed S; Faculty of Pharmacy and Health Sciences, Universiti Kuala Lumpur Royal College of Medicine Perak, Greentown, 30450 Ipoh, Perak, Malaysia.
Tahir Ansari M; School of Pharmacy, University of Nottingham Malaysia, Jalan Broga, 43500 Semenyih, Selangor, Malaysia. Electronic address: .
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Źródło :
International journal of pharmaceutics [Int J Pharm] 2022 Apr 25; Vol. 618, pp. 121605. Date of Electronic Publication: 2022 Feb 26.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Neoplasms*/drug therapy
Stilbenes*/pharmacokinetics
Biological Availability ; Humans ; Pharmaceutical Preparations ; Resveratrol/pharmacokinetics
Czasopismo naukowe
Tytuł :
Population pharmacokinetics of tacrolimus in Chinese adult liver transplant patients.
Autorzy :
Teng F; Institute of Organ Transplantation, Second Affiliated Hospital of Naval Medical University, Shanghai, China.
Zhang W; School of Nursing, Beijing University of Chinese Medicine, Beijing, China.
Wang W; Medical Guarantee Center, Second Affiliated Hospital of Naval Medical University, Shanghai, China.
Chen J; Medical Guarantee Center, Second Affiliated Hospital of Naval Medical University, Shanghai, China.
Liu S; Medical Guarantee Center, Second Affiliated Hospital of Naval Medical University, Shanghai, China.
Li M; Medical Guarantee Center, Second Affiliated Hospital of Naval Medical University, Shanghai, China.
Li L; Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Guo W; Institute of Organ Transplantation, Second Affiliated Hospital of Naval Medical University, Shanghai, China.
Wei H; Medical Guarantee Center, Second Affiliated Hospital of Naval Medical University, Shanghai, China.
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Źródło :
Biopharmaceutics & drug disposition [Biopharm Drug Dispos] 2022 Apr; Vol. 43 (2), pp. 76-85. Date of Electronic Publication: 2022 Mar 23.
Typ publikacji :
Journal Article
MeSH Terms :
Liver Transplantation*
Tacrolimus*/pharmacokinetics
Adult ; China ; Cytochrome P-450 CYP3A/genetics ; Genotype ; Humans ; Immunosuppressive Agents/pharmacokinetics ; Models, Biological
Czasopismo naukowe
Tytuł :
Effect of Roxadustat on the Pharmacokinetics of Simvastatin, Rosuvastatin, and Atorvastatin in Healthy Subjects: Results From 3 Phase 1, Open-Label, 1-Sequence, Crossover Studies.
Autorzy :
Groenendaal-van de Meent D; Astellas Pharma Europe B.V., Leiden, The Netherlands.
den Adel M; Astellas Pharma Europe B.V., Leiden, The Netherlands.
Kerbusch V; PharmAspire B.V., Wijchen, The Netherlands.
van Dijk J; Astellas Pharma Europe B.V., Leiden, The Netherlands.
Shibata T; Astellas Pharma, Inc., Tokyo, Japan.
Kato K; Astellas Pharma, Inc., Tokyo, Japan.
Schaddelee M; Astellas Pharma Europe B.V., Leiden, The Netherlands.
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Źródło :
Clinical pharmacology in drug development [Clin Pharmacol Drug Dev] 2022 Apr; Vol. 11 (4), pp. 486-501. Date of Electronic Publication: 2022 Feb 19.
Typ publikacji :
Clinical Trial, Phase I; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
MeSH Terms :
Neoplasm Proteins*
Simvastatin*/adverse effects
Simvastatin*/pharmacokinetics
ATP Binding Cassette Transporter, Subfamily G, Member 2 ; Atorvastatin/adverse effects ; Atorvastatin/pharmacokinetics ; Cross-Over Studies ; Glycine/analogs & derivatives ; Healthy Volunteers ; Humans ; Isoquinolines ; Rosuvastatin Calcium/adverse effects ; Rosuvastatin Calcium/pharmacokinetics
Czasopismo naukowe
Tytuł :
Pharmacokinetics and Bioequivalence of a Generic and a Branded Budesonide Nasal Spray in Healthy Chinese Subjects.
Autorzy :
Li X; Department of Pharmacy, The Third Hospital of Changsha, Changsha, Hunan, China.
Li Y; Department of Pharmacy, The Third Hospital of Changsha, Changsha, Hunan, China.
Xu B; Department of Pharmacy, The Third Hospital of Changsha, Changsha, Hunan, China.
Zhang P; Department of Pharmacy, The Third Hospital of Changsha, Changsha, Hunan, China.
Wang Y; Department of Pharmacy, The Third Hospital of Changsha, Changsha, Hunan, China.
Wang Z; Sichuan Purity Pharmaceutical Co. LTD, Chengdu, Sichuan, China.
Hou S; Sichuan Purity Pharmaceutical Co. LTD, Chengdu, Sichuan, China.
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Źródło :
Clinical pharmacology in drug development [Clin Pharmacol Drug Dev] 2022 Apr; Vol. 11 (4), pp. 516-522. Date of Electronic Publication: 2021 Nov 16.
Typ publikacji :
Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
MeSH Terms :
Budesonide*/adverse effects
Budesonide*/pharmacokinetics
Nasal Sprays*
China ; Cross-Over Studies ; Drugs, Generic/adverse effects ; Drugs, Generic/pharmacokinetics ; Humans ; Tablets ; Therapeutic Equivalency
Czasopismo naukowe
Tytuł :
Development of a genetic algorithm and NONMEM workbench for automating and improving population pharmacokinetic/pharmacodynamic model selection.
Autorzy :
Ismail M; Department of Pharmaceutical Sciences, School of Pharmacy and Pharmaceutical Sciences, University at Buffalo, Buffalo, NY, USA.
Sale M; Nuventra Pharma Sciences, Durham, NC, USA.
Yu Y; Department of Pharmaceutical Sciences, School of Pharmacy and Pharmaceutical Sciences, University at Buffalo, Buffalo, NY, USA.
Pillai N; Department of Pharmaceutical Sciences, School of Pharmacy and Pharmaceutical Sciences, University at Buffalo, Buffalo, NY, USA.
Liu S; Department of Pharmaceutical Sciences, School of Pharmacy and Pharmaceutical Sciences, University at Buffalo, Buffalo, NY, USA.
Pflug B; Roswell Park Cancer Institute, Buffalo, NY, USA.
Bies R; Department of Pharmaceutical Sciences, School of Pharmacy and Pharmaceutical Sciences, University at Buffalo, Buffalo, NY, USA. .; Institute for Computational Data Science, University at Buffalo, Buffalo, NY, USA. .
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Źródło :
Journal of pharmacokinetics and pharmacodynamics [J Pharmacokinet Pharmacodyn] 2022 Apr; Vol. 49 (2), pp. 243-256. Date of Electronic Publication: 2021 Oct 03.
Typ publikacji :
Journal Article
MeSH Terms :
Algorithms*
Pharmacokinetics*
Computer Simulation ; Models, Biological
Czasopismo naukowe

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