- Tytuł :
- Rebiopsy in advanced non-small cell lung cancer, clinical relevance and prognostic implications
- Autorzy :
- Źródło :
- In Lung Cancer June 2022 168:10-20
-
Czasopismo naukowe
Wyszukujesz frazę "Merkelbach, Matthias" wg kryterium: Autor
- Tytuł :
- Comprehensive Analysis of TP53 and KEAP1 Mutations and Their Impact on Survival in Localized- and Advanced-Stage NSCLC
- Autorzy :
- Źródło :
- In Journal of Thoracic Oncology January 2022 17(1):76-88
-
Czasopismo naukowe
- Tytuł :
- Systematic monitoring for detection of atrial fibrillation in patients with acute ischaemic stroke (MonDAFIS): a randomised, open-label, multicentre study
- Autorzy :
- Źródło :
- In The Lancet Neurology June 2021 20(6):426-436
-
Czasopismo naukowe
- Tytuł :
- Clonal dynamics of BRAF-driven drug resistance in EGFR-mutant lung cancer
- Autorzy :
- Temat :
-
Neoplasms. Tumors. Oncology. Including cancer and carcinogens
RC254-282 - Źródło :
- npj Precision Oncology, Vol 5, Iss 1, Pp 1-12 (2021)
- Opis pliku :
- electronic resource
- Relacje :
- https://doaj.org/toc/2397-768X
- Dostęp URL :
- https://doaj.org/article/2fe94ce5763c49248add719a2c82fe60
-
Czasopismo naukowe
- Tytuł :
- Clonal dynamics of BRAF-driven drug resistance in EGFR-mutant lung cancer
- Autorzy :
- Źródło :
- npj Precision Oncology. 5(1)
-
Czasopismo naukowe
- Tytuł :
- Cancer-specific immune evasion and substantial heterogeneity within cancer types provide evidence for personalized immunotherapy
- Autorzy :
- Źródło :
- npj Precision Oncology. 5(1)
-
Czasopismo naukowe
- Tytuł :
- Genetic Heterogeneity of MET-Aberrant NSCLC and Its Impact on the Outcome of Immunotherapy
- Autorzy :
- Źródło :
- In Journal of Thoracic Oncology April 2021 16(4):572-582
-
Czasopismo naukowe
- Tytuł :
- Harmonization and Standardization of Panel-Based Tumor Mutational Burden Measurement: Real-World Results and Recommendations of the Quality in Pathology Study
- Autorzy :
- Źródło :
- In Journal of Thoracic Oncology July 2020 15(7):1177-1189
-
Czasopismo naukowe
- Tytuł :
- Detection of circulating tumor DNA by digital droplet PCR in resectable lung cancer as a predictive tool for recurrence
- Autorzy :
- Źródło :
- In Lung Cancer January 2021 151:91-96
-
Czasopismo naukowe
- Tytuł :
- Cancer-specific immune evasion and substantial heterogeneity within cancer types provide evidence for personalized immunotherapy
- Autorzy :
- Temat :
-
Neoplasms. Tumors. Oncology. Including cancer and carcinogens
RC254-282 - Źródło :
- npj Precision Oncology, Vol 5, Iss 1, Pp 1-12 (2021)
- Opis pliku :
- electronic resource
- Relacje :
- https://doaj.org/toc/2397-768X
- Dostęp URL :
- https://doaj.org/article/4edee7d56ead4b1585567524e79d56a7
-
Czasopismo naukowe
- Tytuł :
- Co-occurrence of targetable mutations in Non-small cell lung cancer (NSCLC) patients harboring MAP2K1 mutations
- Autorzy :
- Źródło :
- In Lung Cancer June 2020 144:40-48
-
Czasopismo naukowe
- Tytuł :
- Safety and Efficacy of Crizotinib in Patients With Advanced or Metastatic ROS1-Rearranged Lung Cancer (EUCROSS): A European Phase II Clinical Trial
- Autorzy :
- Źródło :
- In Journal of Thoracic Oncology July 2019 14(7):1266-1276
-
Czasopismo naukowe
- Tytuł :
- Sorafenib and everolimus in patients with advanced solid tumors and KRAS‐mutated NSCLC: A phase I trial with early pharmacodynamic FDG‐PET assessment
- Autorzy :
- Temat :
-
FDG‐PET
KRAS mutation
non‐small‐cell lung cancer
pharmacodynamics
pharmacokinetics
Phase‐I trial
Neoplasms. Tumors. Oncology. Including cancer and carcinogens
RC254-282 - Źródło :
- Cancer Medicine, Vol 9, Iss 14, Pp 4991-5007 (2020)
- Opis pliku :
- electronic resource
- Relacje :
- https://doaj.org/toc/2045-7634
- Dostęp URL :
- https://doaj.org/article/04f6918ff70742839866e3f4fa056a57
-
Czasopismo naukowe
- Tytuł :
- K-ras Mutation Subtypes in NSCLC and Associated Co-occuring Mutations in Other Oncogenic Pathways
- Autorzy :
- Źródło :
- In Journal of Thoracic Oncology April 2019 14(4):606-616
-
Czasopismo naukowe
- Tytuł :
- Alterations in ERBB2 and BRCA and microsatellite instability as new personalized treatment options in small bowel carcinoma
- Autorzy :
- Temat :
-
Small bowel adenocarcinoma
BRCA mutation
PARP-inhibition
ERBB2 mutation
Microsatellite-instability
Diseases of the digestive system. Gastroenterology
RC799-869 - Źródło :
- BMC Gastroenterology, Vol 19, Iss 1, Pp 1-6 (2019)
- Opis pliku :
- electronic resource
- Relacje :
- http://link.springer.com/article/10.1186/s12876-019-0942-z; https://doaj.org/toc/1471-230X
- Dostęp URL :
- https://doaj.org/article/6877420e7dd24c4ca9eb6d41ff1a1165
-
Czasopismo naukowe
- Tytuł :
- Overcoming EGFR G724S-mediated osimertinib resistance through unique binding characteristics of second-generation EGFR inhibitors
- Autorzy :
- Temat :
- Science
- Źródło :
- Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
- Opis pliku :
- electronic resource
- Relacje :
- https://doaj.org/toc/2041-1723
- Dostęp URL :
- https://doaj.org/article/d0509a8e9f1241e6a692b9bd9e5d0a9b
-
Czasopismo naukowe
- Tytuł :
- Comprehensive Analysis of TP53 and KEAP1 Mutations and Their Impact on Survival in Localized- and Advanced-Stage NSCLC
- Autorzy :
- Temat :
-
Pulmonary and Respiratory Medicine
Oncology - Źródło :
- Journal of Thoracic Oncology.
- Dostęp URL :
-
https://explore.openaire.eu/search/publication?articleId=doi_________::2d6d7924f1ef5b82c0a8ec5b6e621581
https://api.elsevier.com/content/article/PII:S1556086421031877?httpAccept=text/xml
- Tytuł :
- ALK G1269A mutation as a potential mechanism of acquired resistance to crizotinib in an ALK-rearranged inflammatory myofibroblastic tumor
- Autorzy :
- Temat :
-
Neoplasms. Tumors. Oncology. Including cancer and carcinogens
RC254-282 - Źródło :
- npj Precision Oncology, Vol 1, Iss 1, Pp 1-4 (2017)
- Opis pliku :
- electronic resource
- Relacje :
- https://doaj.org/toc/2397-768X
- Dostęp URL :
- https://doaj.org/article/33a80232e38044a3a05d9a9bbd74b52a
-
Czasopismo naukowe
- Tytuł :
- Genetic Heterogeneity of MET-Aberrant NSCLC and Its Impact on the Outcome of Immunotherapy
- Autorzy :
- Temat :
-
Pulmonary and Respiratory Medicine
Oncology
Cancer research
Genetic heterogeneity
Immunohistochemistry
Lung cancer
medicine.disease
medicine
business.industry
business
Non small cell
Copy-number variation
Immunotherapy
medicine.medical_treatment
MET Exon 14 Mutation
Overall survival - Źródło :
- Journal of Thoracic Oncology. 16:572-582
- Dostęp URL :
-
https://explore.openaire.eu/search/publication?articleId=doi_________::bc23f7e85f05f773a1ed2d4bef0e7c16
https://api.elsevier.com/content/article/PII:S1556086420310911?httpAccept=text/xml
- Tytuł :
- Implementation of Amplicon Parallel Sequencing Leads to Improvement of Diagnosis and Therapy of Lung Cancer Patients
- Autorzy :
- Źródło :
- In Journal of Thoracic Oncology July 2015 10(7):1049-1057
-
Czasopismo naukowe
- Tytuł :
- Detection of circulating tumor DNA by digital droplet PCR in resectable lung cancer as a predictive tool for recurrence
- Autorzy :
- Temat :
-
Cancer Research
Pulmonary and Respiratory Medicine
Oncology
Medicine
business.industry
business
Prospective cohort study
Internal medicine
medicine.medical_specialty
Primary tumor
medicine.disease
Lung cancer
Stage (cooking)
Cell-free fetal DNA
Germline mutation
Liquid biopsy
Mutation
medicine.disease_cause - Źródło :
- Lung Cancer. 151:91-96
- Dostęp URL :
-
https://explore.openaire.eu/search/publication?articleId=doi_________::b46fa07072e5fcdd9444a4469cc88beb
https://api.elsevier.com/content/article/PII:S016950022030670X?httpAccept=text/xml
- Tytuł :
- Alterations in ERBB2 and BRCA and microsatellite instability as new personalized treatment options in small bowel carcinoma
- Autorzy :
- Źródło :
- BMC Gastroenterology. 19(1)
-
Czasopismo naukowe
- Tytuł :
- Sorafenib and everolimus in patients with advanced solid tumors and KRAS‐mutated NSCLC: A phase I trial with early pharmacodynamic FDG‐PET assessment
- Autorzy :
- Temat :
-
FDG‐PET
KRAS mutation
non‐small‐cell lung cancer
pharmacodynamics
pharmacokinetics
Phase‐I trial
lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens
lcsh:RC254-282
Original Research
Clinical Cancer Research
solid tumors
Cancer Research
Radiology Nuclear Medicine and imaging
Oncology
Pharmacodynamics
Everolimus
medicine.drug
medicine
Sorafenib
medicine.medical_specialty
Lung cancer
medicine.disease
KRAS
medicine.disease_cause
business.industry
business
Internal medicine
Progression-free survival
Pharmacokinetics
Combination therapy
neoplasms - Źródło :
-
Cancer Medicine, Vol 9, Iss 14, Pp 4991-5007 (2020)
Cancer Medicine - Dostęp URL :
-
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6710a42760e313f5ebb3ac2205261983
https://doaj.org/article/04f6918ff70742839866e3f4fa056a57
- Tytuł :
- Harmonization and Standardization of Panel-Based Tumor Mutational Burden Measurement: Real-World Results and Recommendations of the Quality in Pathology Study
- Autorzy :
- Temat :
-
Pulmonary and Respiratory Medicine
Oncology
medicine.medical_specialty
medicine
Confounding
Quality assurance
business.industry
business
Biomarker (medicine)
Lung cancer
medicine.disease
Adenocarcinoma
Deep sequencing
Internal medicine
Head and neck squamous-cell carcinoma
Cut-point - Źródło :
- Journal of Thoracic Oncology. 15:1177-1189
- Dostęp URL :
-
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a0eeec4d06820c234062a7c4a204100
https://api.elsevier.com/content/article/PII:S1556086420301350?httpAccept=text/xml
- Tytuł :
- Overcoming EGFR-mediated osimertinib resistance through unique binding characteristics of second-generation EGFR inhibitors
- Autorzy :
- Źródło :
- Nature Communications. 9(1)
-
Czasopismo naukowe
- Tytuł :
- NTRK testing: First results of the QuiP‐EQA scheme and a comprehensive map of NTRK fusion variants and their diagnostic coverage by targeted RNA ‐based NGS assays
- Autorzy :
- Temat :
-
Cancer Research
Genetics
In situ hybridization
Fluorescence in situ hybridization
medicine.diagnostic_test
medicine
Fusion gene
Gene
Computational biology
RNA
External quality assessment
In silico
Biology
DNA extraction - Źródło :
- Genes, Chromosomes and Cancer. 59:445-453
- Dostęp URL :
-
https://explore.openaire.eu/search/publication?articleId=doi_________::2dbc8ccd2e4ac88ef0ec9de70dee807d
https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fgcc.22853
- Tytuł :
- Co-occurrence of targetable mutations in Non-small cell lung cancer (NSCLC) patients harboring MAP2K1 mutations
- Autorzy :
- Temat :
-
Cancer Research
Pulmonary and Respiratory Medicine
Oncology
ROS1
Mutation
medicine.disease_cause
medicine
non-small cell lung cancer (NSCLC)
medicine.disease
Adenocarcinoma
MAP2K1
Cancer research
Pemetrexed
medicine.drug
Targeted therapy
medicine.medical_treatment
business.industry
business
BRAF V600E
endocrine system - Źródło :
- Lung Cancer. 144:40-48
- Dostęp URL :
-
https://explore.openaire.eu/search/publication?articleId=doi_________::a076f188544b28df91c4987d96ec8628
https://api.elsevier.com/content/article/PII:S0169500220303913?httpAccept=text/xml
- Tytuł :
- ALK mutation as a potential mechanism of acquired resistance to crizotinib in an ALK-rearranged inflammatory myofibroblastic tumor
- Autorzy :
- Źródło :
- npj Precision Oncology. 1(1)
-
Czasopismo naukowe
- Tytuł :
- Abstract CT255: EATON: A phase I dose-escalation trial of nazartinib (EGF816) and trametinib in EGFR-mutant NSCLC
- Autorzy :
- Temat :
-
Oncology
medicine.medical_specialty
medicine
Cancer
medicine.disease
Osimertinib
Rash
medicine.symptom
Adverse effect
Lung cancer
Progressive disease
Trametinib
business.industry
business
Anemia
Internal medicine - Źródło :
- Tumor Biology.
- Dostęp URL :
-
https://explore.openaire.eu/search/publication?articleId=doi_________::073fe33e325b5c48581c2f86ffd34912
https://syndication.highwire.org/content/doi/10.1158/1538-7445.AM2020-CT255
- Tytuł :
- KEAP1 mutations in squamous cell lung cancer
- Autorzy :
- Temat :
-
Cancer Research
Oncology - Źródło :
- Journal of Clinical Oncology. 39:e21098-e21098
- Dostęp URL :
- https://explore.openaire.eu/search/publication?articleId=doi_________::44e82f22f1992a4a664c1a32c717c2ac
- Tytuł :
- K-ras Mutation Subtypes in NSCLC and Associated Co-occuring Mutations in Other Oncogenic Pathways
- Autorzy :
- Temat :
-
Pulmonary and Respiratory Medicine
Oncology
Medicine
business.industry
business
Gene
Receptor tyrosine kinase
biology.protein
biology
KRAS
medicine.disease_cause
Fluorescence in situ hybridization
medicine.diagnostic_test
Kinase
Genetic heterogeneity
Cancer research
Mutation
STK11
neoplasms - Źródło :
- Journal of Thoracic Oncology. 14:606-616
- Dostęp URL :
-
https://explore.openaire.eu/search/publication?articleId=doi_________::126be135328e3f2bcf25497758c58a3b
https://api.elsevier.com/content/article/PII:S1556086418335329?httpAccept=text/xml
- Tytuł :
- Loss of G2032R Resistance Mutation Upon Chemotherapy Treatment Enables Successful Crizotinib Rechallenge in a Patient With ROS1-Rearranged NSCLC
- Autorzy :
- Temat :
-
Cancer Research
Oncology
Crizotinib
medicine.drug
medicine
business.industry
business
Cancer research
Resistance mutation
ROS1
Chemotherapy
medicine.medical_treatment - Źródło :
- JCO Precision Oncology. :1-6
- Dostęp URL :
-
https://explore.openaire.eu/search/publication?articleId=doi_________::7ecd1f654a347126a0cfb045ba3084f0
https://ascopubs.org/doi/pdfdirect/10.1200/PO.18.00121
- Informacja :
- Dostęp do tej pozycji wymaga zalogowania się.
-
Czasopismo naukowe
- Tytuł :
- Testing NTRK testing: Wet‐lab and in silico comparison of RNA‐based targeted sequencing assays
- Autorzy :
- Temat :
-
Cancer Research
Genetics
RNA
Reverse transcription polymerase chain reaction
In silico
Fluorescence in situ hybridization
medicine.diagnostic_test
medicine
Fusion gene
Computational biology
Performance results
Fusion protein
Gene
Biology - Dostęp URL :
- https://explore.openaire.eu/search/publication?articleId=doi_________::66fae09d363edf2650a2d9c1b4257ec4
- Tytuł :
- Down regulation and nuclear localization of human β-defensin-1 in pleomorphic adenomas of salivary glands
- Autorzy :
- Źródło :
- In Oral Oncology 2009 45(6):526-530
-
Czasopismo naukowe
- Tytuł :
- ALK G1269A mutation as a potential mechanism of acquired resistance to crizotinib in an ALK-rearranged inflammatory myofibroblastic tumor
- Autorzy :
- Temat :
-
lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens
lcsh:RC254-282
Case Report
Ceritinib
medicine.drug
medicine
Pathology
medicine.medical_specialty
Cancer research
Adenocarcinoma
medicine.disease
Biology
Anaplastic lymphoma kinase
Mutation
medicine.disease_cause
Mesenchymal stem cell
Targeted therapy
medicine.medical_treatment
Crizotinib
Gene
hemic and lymphatic diseases - Źródło :
-
npj Precision Oncology, Vol 1, Iss 1, Pp 1-4 (2017)
NPJ Precision Oncology - Dostęp URL :
-
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f1199c3a27fda23e94c004ccb50db81
https://doaj.org/article/33a80232e38044a3a05d9a9bbd74b52a
- Tytuł :
- Genomic Profiling Identifies Outcome-Relevant Mechanisms of Innate and Acquired Resistance to Third-Generation Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor Therapy in Lung Cancer
- Autorzy :
- Temat :
-
Original Report
Cancer Research
Oncology
Biology
Genomic profiling
Third generation
Epidermal growth factor receptor
biology.protein
Acquired resistance
Epidermal growth factor receptor tyrosine kinase
Lung cancer
medicine.disease
medicine
Tyrosine kinase
Egfr tki
Cancer research
respiratory tract diseases - Źródło :
- JCO Precision Oncology
- Dostęp URL :
-
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b5cbf4943cb5cf52a50137e024f7f69
http://europepmc.org/articles/PMC7446436
- Tytuł :
- Crizotinib in patients with advanced or metastatic ROS1-rearranged lung cancer (EUCROSS): A European phase II clinical trial – Updated progression-free survival, overall survival and mechanisms of resistance
- Autorzy :
- Temat :
-
Oncology
Hematology
Medicine
business.industry
business
Population
education.field_of_study
education
Progression-free survival
Family medicine
medicine.medical_specialty
Mediolanum
Disease control
Gene deletion
Overall survival
Clinical trial
In patient - Źródło :
- Annals of Oncology. 30:v637-v638
- Dostęp URL :
-
https://explore.openaire.eu/search/publication?articleId=doi_________::35dcb98460e6552f714f6de17dc76ba3
https://api.elsevier.com/content/article/PII:S0923753419597551?httpAccept=text/xml
- Tytuł :
- Alterations in ERBB2 and BRCA and microsatellite instability as new personalized treatment options in small bowel carcinoma
- Autorzy :
- Temat :
-
Gastroenterology
General Medicine
Medicine
business.industry
business
MSH2
KRAS
medicine.disease_cause
Neuroblastoma RAS viral oncogene homolog
Cancer research
MLH1
MSH6
Microsatellite instability
medicine.disease
PMS2
HRAS
Small bowel adenocarcinoma
BRCA mutation
PARP-inhibition
ERBB2 mutation
Microsatellite-instability
lcsh:Diseases of the digestive system. Gastroenterology
lcsh:RC799-869
Research Article
neoplasms
digestive system diseases - Źródło :
-
BMC Gastroenterology, Vol 19, Iss 1, Pp 1-6 (2019)
BMC Gastroenterology - Dostęp URL :
- https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c521dc8abd89bb0e305e1b802ec9af5
- Tytuł :
- Acquired KRAS mutation and loss of low-level MET amplification after durable response to crizotinib in a patient with lung adenocarcinoma
- Autorzy :
- Temat :
-
Cancer Research
Pulmonary and Respiratory Medicine
Oncology
Adenocarcinoma
medicine.disease
medicine
Lung cancer
Biomarker (medicine)
Cancer research
Cancer
KRAS
medicine.disease_cause
business.industry
business
Tyrosine-kinase inhibitor
medicine.drug_class
Crizotinib
medicine.drug
Lung
medicine.anatomical_structure
respiratory tract diseases - Dostęp URL :
- https://explore.openaire.eu/search/publication?articleId=doi_________::07f26c68e988a25a1655bcab07ab8f4b
- Tytuł :
- Monitoring treatment response to Erlotinib in EGFR-mutated nonesmall-cell lung cancer brain metastases using serial O-(2-[18F]fluoroethyl)-L-tyrosine PET
- Autorzy :
- Temat :
-
ddc:610
Cancer Research
Pulmonary and Respiratory Medicine
Oncology
18F-fluoroethyl-L-tyrosine
Cancer research
Lung cancer
medicine.disease
medicine
Treatment response
Non small cell
Carcinoma
business.industry
business
Erlotinib
medicine.drug
Egfr mutation
Positron emission tomography
medicine.diagnostic_test - Źródło :
- Clinical lung cancer 20(2), e148-e151 (2019). doi:10.1016/j.cllc.2018.10.011
- Dostęp URL :
-
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::930a73291c28f530d559486870069c65
https://juser.fz-juelich.de/record/859034
- Tytuł :
- Safety and Efficacy of Crizotinib in Patients With Advanced or Metastatic ROS1-Rearranged Lung Cancer (EUCROSS): A European Phase II Clinical Trial
- Autorzy :
- Temat :
-
Pulmonary and Respiratory Medicine
Oncology
Adenocarcinoma
medicine.disease
medicine
Adverse effect
medicine.medical_specialty
Internal medicine
Response Evaluation Criteria in Solid Tumors
Clinical endpoint
Clinical trial
ROS1
business.industry
business
Crizotinib
medicine.drug
Lung cancer
Targeted treatment
TP53
ROS1 REARRANGEMENTS
ANAPLASTIC LYMPHOMA
ANTITUMOR-ACTIVITY
KINASE INHIBITION
TARGETING ROS1
ALK
ADENOCARCINOMA
CHEMOTHERAPY
MUTATIONS
FUSIONS - Źródło :
- Journal of Thoracic Oncology, 14(7), 1266-1276. Elsevier Science
- Dostęp URL :
- https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09274df74058250ad1cc1423ee3f46f1
- Tytuł :
- Clinical and Pathological Characteristics of KEAP1 - and NFE2L2 -Mutated Non–Small Cell Lung Carcinoma (NSCLC)
- Autorzy :
- Temat :
-
Cancer Research
Oncology
Cancer research
Pathological
Mutation
medicine.disease_cause
medicine
NFE2L2
Cancer
medicine.disease
Carcinoma
Adenocarcinoma
Immunohistochemistry
business.industry
business
Biomarker (medicine) - Dostęp URL :
- https://explore.openaire.eu/search/publication?articleId=doi_________::0be8a3e9db755535fe7f94c4f93fa9e6
- Tytuł :
- Was die neuen Kriterien für die Institute bedeuten.
- Autorzy :
- Źródło :
- Die Bank. 2020, Issue 10, p48-51. 4p.
-
Periodyk